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Biomedical subjects

G W DeBoom

Publications and source records attributed to G W DeBoom.

At least 19 recordsLinked to original sources
PubMed1994

Proliferative myositis of the head and neck. Report of a case and review of the literature.

A case of proliferative myositis arising in the tongue is described. Light and electron micrographs revealed the characteristic infiltrative growth pattern and cellular pleomorphism of this lesion. A review of the literature disclosed 50 reported cases of proliferative myositis, including 10 that originated in the head and neck. The rapid growth rate and unusual gross and histologic appearance of this infiltrative lesion have contributed to its relatively frequent misdiagnosis and inappropriate treatment. Consequently it is hoped that this report will help clarify its benign nature.

Aged↗
PubMed1990

Rapidly enlarging ulcerated lesion of the maxilla.

This report describes a mixed tumor of the left maxilla. The lesion showed rapid growth, 5 years after excision of a mixed tumor from the left side of the hard palate. The extent of the lesion indicates an aggressive tumor that requires close follow-up.

Adenoma, Pleomorphic↗
PubMed1990

Multiple oral and skin lesions occurring after treatment with penicillin.

A case of erythema multiforme has been presented. Erythema multiforme may be a self-limiting or chronic disease, of varying severity. The disease is of significance to dental practitioners who may be called on to establish a diagnosis and provide appropriate referral or treatment, especially when lesions are limited to the mouth. The prognosis is generally good, although recurrence is common.

Adult↗
PubMed1990

Lip paresthesia associated with a jaw mass.

A case is reported in which mandibular swelling and lower lip numbness were the first signs of a metastatic adenocarcinoma of the lung. The development of paresthesia, with or without other oral symptoms, requires that a diagnosis of malignancy be considered until confirmed or ruled out by tissue biopsy. A thorough head and neck examination in all patients, especially in those whose history or habits may indicate increased risk of malignancy is necessary.

Adenocarcinoma↗
PubMed1989

Slow-growing, ulcerated mass of the left posterior hard palate.

The importance of a thorough oral and paraoral examination of all patients, with appropriate follow-up of abnormalities, cannot be overstated. The prognosis of any malignant lesion is improved if diagnosis and treatment are rendered early. This patient had an obvious lesion of the hard palate, 4 1/2 years before definitive diagnosis. When the lesion was first noted, prompt diagnostic evaluation may have discovered the malignant process. The lengthy delay in appropriate treatment for this patient has resulted in a potentially tragic outcome.

Aged↗
PubMed1989

Well-circumscribed, radiopaque, and radiolucent lesion of the anterior maxilla.

In the case reported here, compound composite odontoma was found in a 63-year-old man. Considering the growth characteristics of odontoma, it is likely that this lesion was of at least 45-50 years' duration. The typically asymptomatic nature of the odontoma and its location, apical to the canine and lateral incisor roots, explain why it was not noticed by the patient nor detected by a dentist for many years. Because definitive diagnosis of odontoma is possible only after histopathological examination of the lesion, surgical excision is advised.

Humans↗
PubMed1988

Enlarging soft tissue mass involving the mandibular left alveolar ridge.

The central giant-cell granuloma is a benign, fairly uncommon lesion that can appear clinically and radiographically similar to many other lesions. When histopathological examination discloses a giant-cell lesion of bone, clinical, radiographic, and laboratory data must be obtained and carefully analyzed to rule out such conditions as hyperparathyroidism, Paget's disease, and cherubism, and to confirm the diagnosis of central giant-cell granuloma. Once the diagnosis is established, thorough curettage or surgical excision of the tumor is recommended to assure complete removal. Although recurrence is rare, periodic postoperative examination is also suggested.

Aged↗
PubMed1988

Slowly enlarging pedunculated mass on the edentulous maxillary alveolar ridge.

Peripheral ossifying fibroma is a fairly common, benign, reactive lesion that should be included in the differential diagnosis of slow-growing, nonaggressive tumors arising in the tooth-bearing areas of the jaws. The variations in terms and descriptions may require that the clinician communicate with the pathologist to determine the true nature of the lesion. Although peripheral ossifying fibroma is a benign, reactive lesion, the recurrence rate is fairly high and postoperative follow-up is needed.

Aged↗
PubMed1988

Multilocular radiolucent area of the posterior mandible.

Ameloblastoma is a benign, locally aggressive tumor of odontogenic origin. It is important that the clinician be familiar with this tumor and its variants so that affected patients can be treated adequately and with careful, long-term follow-up.

Aged↗
PubMed1987

Multiple oral and labial ulcers in an immunocompromised patient.

Herpes simplex virus infections in immunocompromised individuals have clinical features that are often quite different from primary and secondary HSV infections in otherwise healthy people. These infections should be recognized early and treated promptly to prevent progression of the lesions and the possible systemic dissemination of the virus. Cytological and biopsy examination frequently discloses changes characteristic of HSV-1, HSV-2, or Varicella-zoster virus. To ensure the most precise diagnosis, however, these examinations should be complemented by viral isolation and serological studies.

Herpes Labialis↗
PubMed1987

Multiple linear ulcers on the dorsum of the tongue in a patient with Waldenstrom's macroglobulinemia.

An unusual clinical presentation of an eosinophilic ulcer of the tongue has been described. This lesion is seen most often in the fourth to sixth decades of life and has been shown to have a strong predilection for males. The etiology is unknown although trauma has been implicated by several investigators. Because of the clinical resemblance of eosinophilic ulcer to carcinoma, biopsy examination is recommended. After the diagnosis is made, conservative management is most appropriate.

Diagnosis, Differential↗
PubMed1987

Painful oral mucosal ulcers in a patient with small cell carcinoma of the lung.

This case illustrates the development of multiple painful oral ulcers caused by methotrexate that was one of a combination of chemotherapeutic drugs administered for the treatment of small cell carcinoma of the lung. Although the oral mucositis is self-limiting and resolves when the drug dose is reduced or therapy is discontinued, severe pain and discomfort may cause physical debilitation. Moreover, the risk of secondary oral infections is high in patients undergoing such therapy, and if the appropriate treatment is not instituted, fatal systemic dissemination of the infection may occur.

Aged↗
PubMed1987

Inverted heart-shaped, interradicular radiolucent area of the anterior maxilla.

A variety of odontogenic, nonodontogenic, and inflammatory conditions may occur between the roots of the maxillary canine and lateral incisor. A list of differential diagnoses might include: odontogenic keratocyst, central giant cell granuloma, odontogenic myxoma, primordial cyst, lateral periodontal cyst, ameloblastoma, and radicular cyst. A diagnosis of globulomaxillary cyst should be noticeably absent from the list, however, and should be considered only after clinical radiographic, and microscopic correlation has effectively ruled out all other possibilities.

Humans↗
PubMed1987

Multiple oral petechiae and ecchymoses in a patient with osteoarthritis.

Ibuprofen is a frequently used medication, and possible drug reactions should be familiar to the clinician. Because oral manifestations of thrombocytopenia are often the initial finding and possibly represent the only clinical evidence of this disease, the dentist should be able to recognize the significance of these lesions and refer the patient for appropriate evaluation and therapy.

Aged↗
PubMed1986

Cylindrical cell papilloma.

A case of cylindrical cell papilloma (CCP) arising in the maxillary sinus is described. Light and electron microscopic findings revealed the characteristic oncocytic nature of the neoplasm. A review of the literature confirms the rarity of CCP and its behavioral similarities to the more common inverted papilloma. The relatively high rate of recurrence, coupled with the increased risk of associated malignancy, necessitates the recognition and appropriate treatment of CCP.

Adenocarcinoma↗
PubMed1986

Persistent, painful ulcerations of the hard palate and buccal mucosa.

C albicans is an opportunistic fungus that produces infection almost exclusively in debilitated or immunocompromised people. The importance of the recognition of candidiasis is not only in the prompt institution of appropriate therapy but also in the identification and treatment of underlying systemic disease. The high rate of occurrence of candidiasis in patients with AIDS or ARC, often as the first symptom, is of significance to the dental practitioner, who may be the first health professional to see such patients.

Candidiasis, Oral↗
PubMed1986

Rapidly developing, edematous swelling of the upper lip.

Clinicians should distinguish between hereditary and non-hereditary angioedema, as management of patients varies significantly with each. As many patients with hereditary angioedema have had serious episodes of edema associated with dental procedures, it is important that dentists understand the nature of this disease and its treatment. The potential for airway obstruction by laryngeal edema requires a knowledge and preparedness for initiation of life-support measures.

Angioedema↗