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Biomedical subjects

G W Dominok

Publications and source records attributed to G W Dominok.

At least 19 recordsLinked to original sources

[Diverticular disease. Pathology and clinical aspects based on 368 autopsy cases].

There were found 368 cases (4.5 percent) of diverticulosis of the intestine based on 8124 autopsies in the years of 1979 till 1988 with regard to their localisation, complications and accompanied diseases. In 174 of 368 cases clinical files could be examined and integrated in the evaluation. Sigmoid diverticula were most frequently followed from duodenal diverticula chiefly in the immediate vicinity of the "Papilla of Vateri". Constipation, stomachache, haemorrhoids and spasm of the anal sphincter were typical complaints. One during lifetime known diverticulosis was noted only approximately half on the autopsy application as a second disease. The autopsy results a complication of diverticula (mostly with a peritonitis) in 39 percent as the primary cause of death. Most frequently complication was a diverticulitis (in 16.8 percent refer to the total number). Arteriosclerosis, hypertension and/or diabetes (so called "civilization diseases") were in the main accompanied diseases, which were found too. Surgical intervention took place principal under suspicion of malignoma or as an "acute abdomen". Non-characteristic complaints (protraction by the physician) and the ignorance of the illness among the population (protraction by the patients) are disadvantageous to the identification of the diverticulosis. Because the diverticulosis as a disease of the economic developed countries represents a growing problem ought to direct more attention to prevention, which consists in application of food rich in ballast-substances and the treatment of the constipation.

Adult

[Classification of primary bone tumors].

An expanded classification for bone tumors is presented based on the well known international classification as well as earlier systems. The current status and future trends in this area are discussed.

Bone Neoplasms

[Pathological anatomy and histology as well as pathogenesis of leg thickness in piglets].

Leg thickness in piglets was found to be an autosomal recessive defect resulting in a primary developmental disturbance of the periosteal and connective components of the soft tissues of the fore- and, less frequently, hindlegs. Histologically there is periosteal thickening with periosteal proliferation of woven bone spiculae and also of myxoid elements of the soft tissue between bone and skin. Similar entities are not known in the human literature. Analogies with human hereditary congenital elephantiasis and pes equinovarus are incorrect.

Animals

[Bone fluorosis].

It is reported on a 80-year-old man with a pronounced bone fluorosis which was ascertained by X-ray findngs, dissection, and determination of the fluor content of the bones. Since there was no professional flour exposition a so-called neighbourhood fluorosis was to be assumed. It was caused by an already naturally increased fluor content of drinking water, which was essentially increased by the sewage of a fluor plant. In addition to this an increased fluor emission was present, since the patient has lived for more than 30 years in the nearest environment of the plant. By suitable measures the prescribed values of the fluor content of drinking water and of the fluor emission have to be kept.

Aged

[Diagnostics and therapy of benign bone tumours (author's transl)].

The diagnosis of benign bone tumours must be confirmed histologically; only in rare cases this can be omitted. After having identified the kind of tumour, a specific therapy must be established, covering a wide range, like excochleation as well as amputation. Malignant degeneration and high rates of relapse are possible.

Bone Neoplasms

[Clinico-pathological comparative studies in plasmacytoma].

A report is given on frequency investigations in the plasmocytoma in a dissection material of 36,985 cases of the years 1951 to 1971. 107 observations of multiple, nearly exclusively osseous plasmocytomas are evaluated concerning frequency of age and sex, affection of the skeleton as well as correlations between the degree of the histological maturity of the tumour cells and the produced para-proteins as well as the existence of the Bence-Jones-protein. The findings were compared with those of the literature.

Adolescent