[A case of macroglobulinemic veticuloendothelial sarcoma].
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Biomedical subjects
Publications and source records attributed to G W Korting.
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In two female patients with prolonged maintenance hemodialysis, blisters and postbullous erosions could be observed. One case also showed raised amounts of uroporphyrin I and III in the urine.
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An additional case of "reticular hyperplasia" is described. The clinical picture is trimorphic with grouped nodules, spinulosismus-like and parapsoriasiform lesions. Histologically there are dense lymphoreticular, partly eosinophilic infiltrates with leucocytoclastic cell aggregates, which, however, do not resemble mycosis fungoides nor a reticulosis. The causative agent was most likely the external use of remedy for an amputation stump containing ethereal oils, which had been used over decades. Positive provocation tests confirmed the diagnosis.
In 150 patients with different dermatoses and 15 controls the activity of collagen peptidase in serum was determined. No relation to specific skin diseases was found. Negative findings were also observed in the group of collagenoses: only 4 of 14 patients with progressive systemic sclerosis showed an increase of this enzyme activity. These negative results seem noteworthy because it thus is demonstrated that alterations of collagen structure are not necessaryly associated with alterations of collagen peptidase activity.
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