SYNOVITIS IN RABBITS DURING BACTEREMIA AND VACCINATION.
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Biomedical subjects
Publications and source records attributed to G W LEWIS.
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Adrenal ascorbic acid was determined in nonstressed, newborn rats. The maturational pattern of the acid consists of high resting levels early in development, a marked decrease during a period between 8 and 12 days, and a subsequent return to high levels. The onset of the maturational pattern is accelerated by previous manipulation of the newborn rat.
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Manipulated infant rats respond to cold with depletion of adrenal ascorbic acid (AAA) significantly earlier than nonmanipulated infants. The study discussed in this report examined the critical period for infantile manipulation on the depletion of AAA. It was found that infant rats manipulated immediately following birth exhibited significant AAA depletion, whereas infants manipulated later did not exhibit depletion.
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