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Biomedical subjects

G W Nuber

Publications and source records attributed to G W Nuber.

At least 19 recordsLinked to original sources

Stiffness, viscosity, and upper-limb inertia about the glenohumeral abduction axis.

To evaluate the dynamic properties of the shoulder and understand how they are controlled by the central nervous system, glenohumeral-joint stiffness and viscosity and upper-limb inertia were quantified under various levels of muscle contraction in seven healthy human subjects. Through a cast attachment, the upper limb was perturbed in a precise pattern by a computer-controlled servomotor to manifest the dynamic properties of the joint. The recorded joint position and torque were used to estimate joint stiffness and viscosity and upper-limb inertia. With moderate muscle contraction, the stiffness and viscosity increased several fold. A stiffer shoulder joint associated with stronger muscle contraction made the shoulder more stable and protected it from potential injuries during strenuous tasks. Joint viscosity, especially the stronger viscous damping associated with more strenuous contraction, smoothed shoulder movement and stabilized the joint. From the control viewpoint, the glenohumeral joint responded to the central nervous system more quickly with increasing muscle contraction, which was useful during strenuous tasks. On the other hand, the central nervous system controlled stiffness and viscosity synchronously so that it dealt with only a nearly constant damping ratio of the joint over various levels of contraction, which simplified its task substantially. This approach quantified the dynamic and static properties of the shoulder under various levels of contraction more accurately and completely than a manual test, and it can potentially be used to evaluate changes in these properties caused by musculoskeletal injuries and their surgical treatments.

Adult↗

Moment distribution among human elbow extensor muscles during isometric and submaximal extension.

To understand better how the central nervous system (CNS) distributes a joint moment among muscles, moment distribution among the three heads of the triceps and the anconeus muscles during isometric elbow extension was quantified in vivo and noninvasively. Electrical stimulation was used to activate an individual muscle selectively at various contraction levels, and the relationship between the peak M-wave amplitude and peak elbow extension moment was established across various contraction levels for each muscle. The relationship was then used to calibrate the corresponding EMG signal and determine moment distribution among the muscles during voluntary isometric elbow extension. Results showed that moment distribution among muscles was not proportional to the muscles' physiological cross-sectional areas (PCSA) and the CNS favored uniarticular muscles for the isometric task performed: the uniarticular lateral and medial heads of the triceps were dominant (contributing approximately 70-90% of the total elbow extension moment) and the anconeus contributed significantly, especially at the lower levels of elbow extension moment (up to approximately 15% of the extension moment). In contrast, the two-joint long head of the triceps contributed significantly less than the uniarticular heads of the triceps. While the absolute contributions of all the muscles increased with the total elbow extension moment, the relative contributions of the muscles may increase or decrease with the elbow extension moment. Cross-validation using fresh data (not used in determining the moment distribution) showed close match between the measured and predicted elbow extension moment except for trials in which fatigue became significant.

Elbow↗

Engineering bone regeneration with bioabsorbable scaffolds with novel microarchitecture.

Critical-sized defects (CSDs) were introduced into rat calvaria to test the hypothesis that absorption of surrounding blood, marrow, and fluid from the osseous wound into a bioabsorbable polymer matrix with unique microarchitecture can induce bone formation via hematoma stabilization. Scaffolds with 90% porosity, specific surface areas of approximately 10 m2/g, and median pore sizes of 16 and 32 microm, respectively, were fabricated using an emulsion freeze-drying process. Contact radiography and radiomorphometry revealed the size of the initial defects (50 mm2) were reduced to 27 +/- 11 mm2 and 34 +/- 17 mm2 for CSDs treated with poly(D,L-lactide-co-glycolide). Histology and histomorphometry revealed scaffolds filled with significantly more de novo bone than negative controls (p < 0. 007), more osteoid than both the negative and autograft controls (p < 0.002), and small masses of mineralized tissue (< 15 mm in diameter) observed within the scaffolds. Based on these findings, we propose a change in the current paradigm regarding the microarchitecture of scaffolds for in vivo bone regeneration to include mechanisms based on hematoma stabilization.

Absorbable Implants↗

Neurovascular problems in the forearm, wrist, and hand.

This article attempted to summarize the most common neurovascular injuries of the upper extremity, particularly the forearm, wrist, and hand. Although these injuries are rarely encountered in athletes, their pathology and treatment must be understood by the treating physician. Failure to recognize these injuries in a timely manner can lead to delay in diagnosis and weeks or months of lost participation by the athlete. The sports medicine physician must be aware of the potential risk for injury to the neurovascular structures, particularly in the athlete exposed to repetitive use or impact of the upper extremity. Timely recognition, diagnosis, and treatment will avoid the potential risk for permanent injury.

Athletic Injuries↗

Olecranon stress fractures in throwers. A report of two cases and a review of the literature.

The evaluation and treatment of elbow injuries in throwing athletics has been the topic of numerous articles. The intense and repetitive stresses placed on the elbow may, in rare instances, produce undisplaced olecranon stress fractures. Two cases are presented and the literature is reviewed to propose that the fractures can be successfully treated by conservative methods.

Adult↗

Biomechanics of the foot and ankle during gait.

Running is a very popular activity, whether for competition or fitness. Breakdown injuries related to training errors, shoe wear, or change in intensity are frequently seen by the sports medicine physician. In order to understand and treat the pathologic situation, a fundamental understanding of the biomechanics of walking and running is essential. The treating practitioner must appreciate the distinct differences between the walking and running gait. These differences transcend a simple increase in speed of gait and include distinct changes in joint range of motion and electromyographic activity. Armed with this knowledge, the practitioner treating a breakdown injury can work to a solution based on scientific understanding rather than anecdotal information.

Ankle↗

Biomechanics of the foot and ankle during gait.

Running is a very popular activity, whether for competition or fitness. Breakdown injuries related to training errors, shoe wear, or change in intensity are frequently seen by the sports medicine physician. In order to understand and treat the pathologic situation, a fundamental understanding of the biomechanics of walking and running is essential. The treating physician must appreciate the distinct differences between the walking and running gait. These differences transcend a simple increase in speed of gait and include distinct changes in joint range of motion and electromyographic activity. Armed with this knowledge, the physician treating a breakdown injury can work to a solution based on scientific understanding rather than anecdotal information.

Ankle↗

Surgical management of adult scoliosis.

In a retrospective analysis of 62 adult scoliotic patients with an average age of 34 years, 39 patients were treated by single-stage posterior fusions, 19 by Harrington instrumentation, and 20 by Luque instrumentation. Twenty-three patients had staged scoliotic procedures. Overall there was a 47% incidence of complications, with the lowest rate, 20%, found in those patients undergoing single-stage posterior fusion with Luque instrumentation. A 16.7% incidence of pseudarthrosis was found in those patients undergoing posterior fusion with Harrington instrumentation. Pseudarthrosis was not found in patients fused posteriorly with Luque instrumentation or with staged anterior and posterior instrumentation.

Adult↗

Refracture of proximal fifth metatarsal (Jones) fracture after intramedullary screw fixation in athletes.

This study details six instances of refracture of clinically and radiographically healed fractures of the base of the fifth metatarsal after intramedullary screw fixation. Four professional football players, one college basketball player, and one recreational athlete underwent intramedullary screw fixation of fifth metatarsal fractures. The athletes were released to full activities an average of 8.5 weeks (range, 5.5 to 12) after fixation, when healing was clinically and radiographically documented. Three football players developed refracture within 1 day of return to full activity. The other three athletes refractured at 2.5, 4, and 4.5 months after return to activity. Two football players underwent repeat fixation with larger screws and returned to play in the same season. The college basketball player underwent bone grafting and returned to play in subsequent seasons. The other three athletes underwent nonoperative management and healed uneventfully over 6 to 8 weeks. On the basis of this series, we recommend that 1) screw fixation using a large-diameter screw should be given careful consideration for patients with large body mass for whom early return to activity is important; 2) functional bracing, shoe modification, or an orthosis should be considered for return to play; 3) if refracture occurs, exchange to a larger screw may allow return to play in the same season; and 4) alternative imaging should be considered to help document complete healing.

Adult↗

Fine wire electromyography analysis of muscles of the shoulder during swimming.

Fine wire EMG of the shoulder was performed on 11 swimmers; 5 performed during dry land studies and 7 during aquatic studies. One individual underwent both studies. A cinematographic analysis was synchronized with the EMG data to determine what muscles were firing at each phase of the swim stroke. Eight muscles were studied: biceps, subscapularis, latissimus dorsi, pectoralis major, supraspinatus, infraspinatus, serratus anterior, and deltoid. Three strokes were analyzed: freestyle, breaststroke, and butterfly. The freestyle and butterfly are frequently associated with impingement type syndromes in swimmers. It was determined that the supraspinatus, infraspinatus, middle deltoid, and serratus anterior were predominately recovery phase muscles. The latissimus dorsi and pectoralis major were predominately pull-through phase muscles. The biceps had mixed inconsistent activity during both phases. From dry land quantifications of the EMG signal it was determined that the serratus anterior functions near maximal muscle test during each stroke, and theoretically may fatigue with repetition. It is hoped that a training program aimed to strengthen the scapular rotators may help alleviate impingement syndrome in swimmers.

Adult↗

Arterial abnormalities of the shoulder in athletes.

Vascular lesions of the shoulder may be misinterpreted as one of the more familiar shoulder abnormalities by a treating physician. We are reporting on 13 athletes who were found to have symptoms related to compression of the subclavian or axillary artery or their tributaries. Nine were amateur or professional baseball pitchers. Severe arm fatigue or finger ischemia, secondary to embolization, were presenting symptoms. Arm fatigue was noted in all pitchers. After complete history and physical examination, including auscultation for bruits in functional positions, all athletes were evaluated by noninvasive tests (Doppler and Duplex scanning). Arteriography was performed with positional testing, recreating overhead activity, and complete radiographic visualization of the dye to the digital arteries. Two patients were found to have subclavian artery aneurysm. The remaining athletes were found to have compression of the subclavian artery beneath the anterior scalene muscle (five patients), the axillary artery beneath the pectoralis minor (two patients), both arterial segments (two patients), and one was found to have arterial compromise at the level of the humeral head. Branch artery compression was also noted. One pitcher occluded the posterior circumflex humeral artery with embolization to the digit. The two patients with subclavian aneurysms underwent saphenous vein bypass with cervical rib resection. All of the other athletes except one underwent resection of a 2 to 3 cm segment of the anterior scalene muscle or pectoralis minor muscles. All returned to their previous level of activity except one patient who developed impingement type symptoms and required acromioplasty. He is currently undergoing rehabilitation. Proper recognition of vascular compromise in the upper extremity of athletes is essential to avoid the catastropic complications of arterial thrombosis.

Athletic Injuries↗

Arterial abnormalities of the hand in athletes.

Vascular lesions of the hand may be seen in athletes exposed to repetitive blunt trauma. Thirteen athletes seen from 1983 to 1988 experienced symptoms related to hand ischemia. Nine were professional baseball catchers. The majority of patients complained of chronic symptoms, including cold hypersensitivity (four patients), finger numbness (one), finger coolness (three), and finger blanching (three). Two patients had acute symptoms with sudden posttraumatic hand ischemia with finger and palmar pain. Diagnosis was established by history and physical examination and confirmed by noninvasive testing. Testing included use of Doppler examination and cold tolerance examination with thermistors. Two athletes required angiographic evaluation because of severe ischemia and continuous pain. All patients in this group were managed nonoperatively. Those with chronic complaints were counseled regarding cold avoidance and instructed to increase their glove padding. The two patients with acute symptoms required vasodilator (papaverine chloride) infusion, followed by intravenous heparin and dextran. All baseball catchers returned to their sport with dissipation of symptoms.

Arteries↗

The contribution of the glenohumeral ligaments to anterior stability of the shoulder joint.

The purpose of this study was to investigate the ligamentous stabilizing mechanisms preventing anterior instability in the glenohumeral joint. Six freshly thawed, unembalmed cadaveric shoulders were dissected, preserving the joint capsule and glenohumeral ligaments, the coracohumeral ligament, and the subscapularis tendon. Hall-effect strain transducers were placed on the superior, middle, and inferior glenohumeral ligaments. The humerus and scapula were fixed in a specifically designed mounting apparatus that allowed the glenohumeral joint to be placed in 0 degree, 45 degrees, or 90 degrees of abduction. The mounting apparatus was placed in a model TTC Instron Universal Testing Instrument, which applied an external rotation torque to the humerus. Strain produced in the three glenohumeral ligaments was recorded on a three-channel X-Y chart recorder. At 0 degree of abduction, the superior and middle glenohumeral ligaments developed the most strain. At 45 degrees of abduction, the inferior and middle glenohumeral ligaments developed the most strain, with considerable strain also being developed in the superior glenohumeral ligament. At 90 degrees of abduction, the inferior glenohumeral ligament developed the most strain, with strain also seen in the middle glenohumeral ligament.

Biomechanical Phenomena↗