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Biomedical subjects

G W Tate

Publications and source records attributed to G W Tate.

12 recordsLinked to original sources

Is asteroid hyalosis ocular gout?

In 76 cases of asteroid hyalosis, seven (9.2%) had gout, eight (10.5%) had close relatives with gout, and two (2.6%) were in both categories. Three of the gouty seven were receiving gout medications. Serum uric acid measurements were elevated in 28.3% of the 46 cases (60.5%) measured. In the 68 monocular cases (89.5%), whites (57 cases) showed no right/left predilection, but blacks (11 cases) had 100% left eye involvement (P less than .001). From a review of 49,000 records, prevalence rates were calculated for discrete age and sex groups. Females under age 60 had no asteroid hyalosis. After age 60 they had a constant prevalence rate of one case per 600 (0.15%). Males of all ages had a higher prevalence rate than females, increasing with age to one per 126 (0.79%) in the 80-or-older group. In all 76 patients, the male-to-female ratio was 1.45:1. Among whites it was, 1.74:1, and among blacks, 0.63:1.

Age Factors↗

Immunocompetence and transfer factor therapy in uveitis.

A study of the clinical course of 20 patients with uveitis treated with transfer factor is reported. Twelve (60%) of the patients were initially immunoincompetent on screening. Eight of the 12 changed to an immunocompetent status after treatment and could either decrease or discontinue their anti-inflammatory drugs. Five had a statistically significant improvement in visual acuity. One of the 8 initially immunocompetent patients had a statistically significant visual improvement, and 2 decreased or discontinued all drugs, while 3 increased their drugs.

Adolescent↗

Capsular delamination (true exfoliation) of the lens. Report of a case.

This report describes a patient with true exfoliation of the lens capsule. Recurrent anterior uveitis eventually necessitated lens extraction from the left eye. Scanning and transmission electron microscopy demonstrated areas of capsular dehiscence and evidence of in vivo cellular degeneration. A comparison of true and pseudoexfoliation of the lens capsule is made and the term "capsular delamination" is proposed for the case reported.

Cataract↗

A new technique for the surgical repair of cyclodialysis induced hypotony.

A new technique for the treatment of cyclodialysis induced hypotony is presented along with the results achieved in 4 cases. The technique is best suited to large clefts, or those in which conservative therapy has failed. No serious sequelae resulting from the procedure were noted in any of our cases.

Adolescent↗

Clindamycin in the treatment of human ocular toxoplasmosis.

Clindamycin was used systemically and periocularly to treat six patients with ocular toxoplasmosis who had a total of eight attacks. Although it appeared to quiet the attack promptly, several side effects were noted. Transient diplopia occured after large periocular doses and papillitis resulted from retrobulbar administration. Despite its efficacy, the results do not seem to warrant high systemic doses for prolonged periods in view of its systemic toxicity. Clindamycin may be most useful as a periocular injection in moderate dosage. A controlled double-blind study is needed.

Adult↗

A coaxial electrode for intraocular diathermy.

A bipolar electrode was used in intraocular coagulation of vessels. This device was a useful adjunct for the coagulation of vessels in diabetic eyes undergoing vitrectomy. No surgical complications due to the diathermy occurred in the first six patients on whom the device was used.

Diabetic Retinopathy↗