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Biomedical subjects

G W Yu

Publications and source records attributed to G W Yu.

8 recordsLinked to original sources
PubMed1996

The patterns of dental caries of preschool children in Kaohsiung City Taiwan.

In order to understand caries patterns, we investigated the severity of caries and the distribution of decayed teeth in 1,654 preschool children aged 3-6 years old in Kaohsiung, Taiwan. The results of our investigation were as follows: the lower second molars had the highest percentage of caries followed by the upper central incisors in the deciduous teeth. The distribution of decayed surfaces in the upper dentition indicated that the occlusal surface of molars, the labial surface of canines, and the mesial and labial surfaces of incisors had relatively high percentages of caries in all age groups. In the 3 year-old children, labial caries on the four upper anterior teeth and no caries in the lower anterior teeth is basically similar to baby bottle tooth decay. Most caries remained in the enamel at this stage. Dentin caries and pulp involved caries became more complex and multiple surfaces were involved in both 5 and 6 year-old children. We therefore suggest that 6, 18, and 30 month-old babies, at the time of vaccination, should have an oral examination as well, and the prevention program for baby bottle tooth decay plus oral hygiene instructions should also be given to the parents. Dentists, pediatricians, gynecologists, and family doctors should all participate in the prevention program against baby bottle tooth decay. For 3 year-old children who already have caries, increasing the filling rate for them should be a very important thing to do for pedodontic specialists and general dental practitioners alike.

Age Distribution↗
PubMed1995

Vascular interventions for impotence: lessons learned.

PURPOSE: The purpose of this study was to analyze the results of vascular interventions for impotence in men with this complaint. METHODS: Between September 1983 and March 1993, 1094 men with the chief complaint of impotence (average age 54.5 years) were screened by use of penile plethysmography and penile brachial indexes: 635 were considered to have normal flow, and 459 were considered to have abnormal arterial flow, 12.2% of whom were found to have aortoiliac disease. Based on negative neural screening results, absence of erectile responses on increasing doses of intracavernously injected papaverine or prostaglandin E1 (ICI), surgical candidates for microvascular procedures were referred for dynamic infusion cavernosography (DICC) and pudendal arteriography. Operations for men discovered to have aortoiliac disease were based on conventional indications including aneurysm size or limb ischemia. None of the subjects had diabetes. Only those patients without diabetes and those not requiring blood pressure medications were selected for microvascular procedures. We report our experience and surgical outcomes at average follow-ups of 33 to 48 months. Four types of operations were performed on 67 men (age 18 to 79 years). These included 17 aortoiliac reconstructions, 11 dorsal penile artery bypasses, 12 dorsal vein arterializations, and 27 venous interruptions. Follow-up data were obtained by direct examination and noninvasive Doppler examinations; repeat arteriography (4 of 11); repeat DICC after venous ablation procedures (18 of 27) and postoperative ICI response. Mail questionnaires completed postoperative surveillance. RESULTS: Among 17 men undergoing aortoiliac intervention for aneurysms in eight and occlusive disease in nine, 58% functioned spontaneously after operation and 18% used ICI or vacuum constrictor devices at an average follow-up time of 38 months. Among 11 men with dorsal penile artery bypasses, 27% functioned spontaneously and 45% used ICI at an average follow-up time of 34.5 months. Among 12 men with dorsal vein arterialization, 33% functioned spontaneously, and 47% used ICI at an average follow-up time of 48 months. Among 27 with venous interruption, 33% functioned spontaneously and 44% used ICI. In seven of eight aneurysms of 4.5 to 6.0 cm in size, impotence workup led to discovery; probable embolic mechanisms existed in three. Venous interruption efficacy correlated with postoperative DICC results when flow to maintain erection was 40 ml or less. Apart from two cases of glans hyperemia, no surgical complications occurred in the microvascular procedures. There was one episode of bleeding caused by DICC after aortic reconstruction. There were no deaths. CONCLUSIONS: With prospective screening criteria, 6% to 7% of impotent men became candidates for vascular intervention. Including those functioning with ICI or vacuum constriction devices, about 70% of these men were functional after operation. Men undergoing aortoiliac reconstruction has a significantly higher rate (58%) of spontaneous function as compared with those undergoing microvascular procedures.

Adolescent↗
PubMed1992

Preoperative and postoperative dynamic cavernosography and cavernosometry: objective assessment of venous ligation for impotence.

A total of 11 men (mean age 51.4 years, 1-year followup) with venous leakage impotence underwent surgical venous ligation. Of the men 8 had erections twice per week immediately after the procedure but at 3 months only 2 remained potent. Dynamic pharmacological cavernosography and cavernosometry were repeated 3 months postoperatively and 6 of the 11 men had venous leakage. These men with venous leakage underwent percutaneous embolization with platinum coils and 4 had successful results. Three additional men became potent after embolization. Of the 11 men 9 are documented to have normal dynamic cavernosography and cavernosometry findings after the combination of an operation and embolization, and 5 are potent. The postoperative and post-embolization dynamic cavernosometry data show that all 11 men have a marked decrease in the flow to maintain erection. Eight men have erections with papaverine or prostaglandin E1 intracorporeal injections. Postoperative dynamic cavernosography and cavernosometry can be diagnostic as well as therapeutic with embolization.

Adult↗
PubMed1981

The characterization of a newly identified, highly metastatic variety of Dunning R 3327 rat prostatic adenocarcinoma system: the MAT LyLu tumor.

The Dunning R 3327 AT tumor is a rapidly growing, androgen insensitive, serially transplantable rat tumor of prostatic origin. In early passages, the AT tumor had a very low rate of distant metastases (less than 1 per cent); however, after 60 serial subcutaneous passages, the AT tumor has given rise to a new tumor line which has an extremely high metastatic rate. Greater then 75 per cent of all animals inoculated with this late passage tumor develop lymph node metastases alone or in combination with lung metastases. This high passage tumor seems to be distinct from the original AT tumor since it has a substantially faster doubling time and a massively increased metastatic potential; it has therefore been named the Dunning R 3327 MAT LyLu tumor (metastatic AT tumor able to disseminate to lymph nodes and lung). The MAT LyLu tumor, like the parent nonmetastatic AT tumor, is androgen insensitive with regard to its growth rate, rate of distant metastases and mean survival time. This newly characterized MAT LyLu tumor provides an appropriate animal model system for testing the potential effectiveness of a variety of therapeutic approaches specifically aimed at limiting the metastatic spread of prostatic cancer.

Adenocarcinoma↗
PubMed1979

Ovarian involvement in neuroblastoma.

A case of neuroblastoma involving the ovaries bilaterally at diagnosis is reported. A review of previous cases of neuroblastoma at Johns Hopkins Hospital revealed no previous occurrence of ovarian metastatic disease at diagnosis, but involvement in about one-third of cases at autopsy. This appears to be a more common site of metastatic disease than has been previously recognized. The significance of this site of metastases in neuroblastoma is unknown.

Adrenal Gland Neoplasms↗