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G Wheeler

Publications and source records attributed to G Wheeler.

20 records · Page 2Linked to original sources

Research on research.

The AOA Committee on Basic and Applied Research sent a questionnaire to all Oregon optometrists requesting information on their attitudes toward 1) research areas to be emphasized in the schools, 2) funding sources for research, and 3) optimum ways of reporting research results. The majority of the O.D.s responding felt that new equipment and techniques, contact lenses, and vision training should be given first priority as research areas, and felt that 5% or more of their AOA dues should be devoted to research. The Journal of the AOA was reported to be the most helpful of all the optometric journals in presenting research information and the vast majority of O.D.s responding selected a complete article with an abstract as the most appropriate report style.

Attitude↗

Flow cytometric analysis of lymphocytes from rats following chronic ethanol treatment.

The current investigation focused on lymphoid cell populations of adult male Sprague-Dawley rats fed a total enteral nutrition diet in which ethanol provided 38% of the total calories. Rats received the National Research Council (NRC) recommended daily intake of nutrients 35 days. An evaluation of lymphocyte populations from peripheral blood demonstrated a decrease in the absolute number of B cells (p < or = 0.007) and absolute numbers of CD4 T cells (p < or = 0.06) in the ethanol-treated animals. Spleen and thymus weights were significantly reduced (p = 0.0001) in the ethanol-treated rats and the CD4/CD8 ratio of splenic lymphocytes decreased in the ethanol group (p < or = 0.03). Thymus T-cell recovery from the ethanol-treated group was significantly reduced with no apparent redistribution in subset numbers with the exception of a minor, yet significant, decrease (p < or = 0.05) in the CD4/CD8 ratio. These data are the first to demonstrate that chronic alcohol intake alters lymphoid cell populations in the peripheral blood and primary organs of the immune systems in the presence of adequate nutrition.

Animals↗