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Biomedical subjects

G Wickström

Publications and source records attributed to G Wickström.

30 records · Page 2Linked to original sources

Occupational skin diseases in shipyard workers.

We have determined the prevalence of skin disorders in shipyard workers by means of an epidemiological cross-sectional study. Of 2057 employees answering a questionnaire, 16% reported present skin lesions. The employees in five chosen trades, altogether 355 persons, were seen by a nurse, who referred all cases of present skin lesions to a dermatologist for further examination. Occupational eczema was found in 11% of the 66 cleaners, 10% of the 94 carpenters, while no case was found among the 71 office workers. Of the 20 cases of occupational eczema, 5 were allergic and 15 irritant. The arms and legs were afflicted as commonly as the hands.

Absenteeism↗

Drawbacks of clinical diagnoses in epidemiologic research on work-related musculoskeletal morbidity.

Register data on musculoskeletal morbidity in various occupational groups are difficult to use in evaluating possible effects of work because of the inexactness of the definition of the clinical diagnoses and their use in ordinary medical practice. A more precise classification of disorders and ailments would provide a better possibility to establish those relations between work and disease which to exist. Internationally recommended methods for epidemiologic research on occupational musculoskeletal disorders are needed.

Bone Diseases↗

Quantitation of CSF concentrations and biological activity of probenecid metabolites.

The concentrations of probenecid and four of its metabolites have been examined in plasma and CSF by electron capture gas chromatography after extractive methylation. The plasma concentration of each of the metabolites was in the range 1,5-15 micrograms/ml and constituted less than 10% of the parent compound. The penetration into CSF of the metabolites was lower than that of probenecid. The concentration of each of the metabolites was below 0,2 microgram/ml and the total concentration never exceeded 10% of the probenecid concentration. The inhibitory effect of the metabolites on uptake was tested in rabbit renal cortex using 3H-p-amino-hippuric acid. The inhibitory effect was low. From the low activity and relatively low concentrations of the metabolites do not contribute to the probenecid-induced blocking effect of acid transport from the CSF.

Animals↗

Load on back in concrete reinforcement work.

The demands of work on the back of concrete reinforcement workers was determined through 4,327 observations of the various work postures and the weights lifted. Static loads from forward-leaning and bent-double postures were found to be common. In the preparation of intermediate and thick rods, forward-leaning was required for more than a third of the total work time, while one central assembly task required work in the bent-double posture for 58% of the total work time. The dynamic loads were of less importance, even though weights over 30 kg were lifted about 15% of the time in the preparation tasks and momentary forces approaching 1,000 N were occasionally needed. The bent-double posture, combined with or quickly followed by additional strain from, for example, weight lifting or slipping, was considered the most probable cause for possible signs of accelerated lumbar disc degeneration, while also the forward-leaning postures could be responsible for reversible low-back symptoms.

Adult↗

Symptoms and signs of degenerative back disease in concrete reinforcement workers.

Concrete reinforcement work causes great static loads on the back from the prolonged adoption of bent-double work postures during the tying of steel rods and from substantial dynamic loads during the lifting and pulling of rods from the stack. Subjective manifestations and objective signs of "degenerative back disease" are common in active reinforcement workers. An age- and sex-adjusted comparison of the findings was, however, possible only with one other occupational group, computer technicians, who also often work in awkward positions. A history of sciatica and pain during forward bending in a clinical examination were significantly more common in reinforcement workers than in computer technicians. This finding suggests an effect of reinforcement work on the back, but definite conclusions require further study.

Adult↗