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Biomedical subjects

G Wilde

Publications and source records attributed to G Wilde.

8 recordsLinked to original sources

Evaluating performance with high-frequency emphasis amplification.

Hearing aid fitting for individuals with high-frequency impairment has been difficult because of the limited gain available at those frequencies. Special high-frequency emphasis hearing aids have been developed in an attempt to alleviate this problem. The insertion-gain responses and changes in speech-recognition performance (in quiet and in noise, aided and unaided) were measured for a commercially available high-frequency emphasis hearing aid, using two types of speech materials (nonsense syllables, monosyllabic words). The maximum obtainable gain observed for high frequencies approximated that prescribed by the NAL-R method, but was considerably lower than that prescribed by other common prescriptive methods. Furthermore, modest improvements in speech recognition were found. When evaluating individuals with high-frequency impairment, speech materials administered in noise appeared to be the most sensitive indication of improved speech recognition. Special high-frequency emphasis speech materials (CUNY NST) were no more sensitive to improvements in performance than conventional clinical word lists (NU6).

Adult

Application of the articulation index to the speech recognition of normal and impaired listeners wearing hearing protection.

The present study examined the application of the articulation index (AI) as a predictor of the speech-recognition performance of normal and hearing-impaired listeners with and without hearing protection. The speech-recognition scores of 12 normal and 12 hearing-impaired subjects were measured for a wide range of conditions designed to be representative of those in the workplace. Conditions included testing in quiet, in two types of background noise (white versus speech spectrum), at three signal-to-noise ratios (+ 5, 0, - 5 dB), and in three conditions of protection (unprotected, earplugs, earmuffs). The mean results for all 21 listening conditions and both groups of subjects were accurately described by the AI. Moreover, a single transfer-function relating performance to the AI could describe all the data from both groups.

Acoustic Stimulation

Defective neutrophil chemotaxis in juvenile periodontitis.

Neutrophil chemotaxis was evaluated in nine patients with juvenile periodontitis, with normal subjects and patients with the adult form of periodontitis as controls. Defective chemotactic responses were observed in neutrophils from seven of nine juvenile patients, and a reduced level of complement-derived chemotactic activity was demonstrated in serum from four patients. These determinations were normal in all the patients with adult periodontitis. Serum from five of the juvenile patients contained a heat-stable, non-dialyzable factor that markedly inhibited the chemotaxis of normal neutrophils. Thus the characteristic tissue destruction seen in juvenile periodontitis may be, at least in part, a consequence of a failure of host defense mechanisms.

Adolescent