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Biomedical subjects

G Wirth

Publications and source records attributed to G Wirth.

At least 37 records · Page 2Linked to original sources
PubMed1986

[Delayed development of hemispheric dominance accompanied by a rare form of retarded language development].

A severe and unusual form of retarded speech development in an eight-year old boy is analyzed as "right-hemispheric speech" against the background of neuropsychological theories on the specialisation of the cerebral hemispheres and considered in connection with the development of hemispheric dominance. A plan for therapy and teacher counselling is derived from this analysis. The influence of this retarded speech development on the acquisition of reading and writing is also touched upon.

Attention↗
PubMed1985

Intolerance to cisplatin--a case report.

A patient who had a systemic reaction to cisplatin chemotherapy had a reaction to subsequent i.c. and i.v. test doses. Notwithstanding she had a more severe systemic reaction during a further course of cisplatin chemotherapy.

Cisplatin↗
PubMed1985

[Allergic contact dermatitis due to Asteraceae (Compositae). Cross reaction with Liatris spicata].

Case reports of 2 florists suffering from contact dermatitis to Asteraceae, especially to Chrysanthema are described. In addition, in both patients allergic patch-test reactions to another Asteraceae species (Liatris spicata) could be demonstrated. This Asteraceae species is a native flower (Blazing Star) in the USA, but in Germany we find the flower in shops, and sometimes in parks and gardens. Genus Liatris contains about 30 species. Numerous sesquiterpene lactons are isolated from Liatris species which are probably cross reactive with sesquiterpene lactons from Asteraceae native to Europe.

Agriculture↗
PubMed1985

[Hypotrichosis congenita hereditaria Maria Unna].

A mother and child are reported, who suffer from hypotrichosis of the Marie-Unna type. At birth they had little or no hair. Subsequently, coarse and wirelike hair grew during early childhood, followed later by alopecia. Examination of the hair using scanning electron microscopy showed peeling of the cuticle and longitudinal ridging. Protein analysis showed no abnormalities compared with normal hair, but there were similarities with the so-called uncombable hair syndrome.

Adult↗
PubMed1984

Inducibility of arylhydrocarbon-hydroxylase activity in human hair follicles by topical application of liquor carbonis detergens (coal tar).

Arylhydrocarbon-hydroxylase (AHH) is a cytochrome P-450-dependent polysubstrate mono-oxygenase which plays an important role in converting some compounds (e.g. benzo[a]pyrene) to highly reactive carcinogenic species. A simple AHH assay is described, using [3H]benzo[a]-pyrene as substrate. 7,8-Benzoflavone (10(-4)M) inhibits 92% of the measured enzyme activity. Liquor carbonis detergens (which contains coal tar) induces AHH activity in human hair follicles in vivo. We suggest that using this simple assay, hair follicles would be a very suitable tissue to test whether the AHH-controlling gene is of significance in producing cancer.

Aryl Hydrocarbon Hydroxylases↗