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G Woodhouse

Publications and source records attributed to G Woodhouse.

4 recordsLinked to original sources
PubMed1999

Erratum

The paper 'Interference of rheumatoid factor activity by aspartame, a dipeptide methyl ester' by Paul A. Ramsland, Bahereh F. Movafagh, Morris Reichlin and Allen B. Edmundson, J. Mol. Recognit. 1999; 12: 249--257, was published without the required colour plates. The publisher would like to apologise for this omission. The article is reprinted here in full. Please replace the previously published pages with those following. The electronic version of the article, including the colour plates, can be downloaded from the Wiley Interscience website at http://www.interscience.wiley.com. The plates have been included in the original paper, which appeared in Issue 4 of the journal.

Journal Article↗
PubMedDate not supplied

The ion channel switch biosensor.

A biosensor technology is described which provides a direct measurement for functional molecular interactions, at the surface of a tethered bilayer membrane, through the electrical transduction of chemically modified ion-channels. High sensitivity of analyte detection is achieved due to the large flux of ions transmitted through the ion channel. The biomimetic sensor surface allows the molecular recognition to be measured in complex biological matrices (such as blood and sera) without compromising sensitivity. We have used the sensor for activity and concentration measurements for a range of analytes, which include bacteria, DNA, proteins and drugs. We have a quantitative model for the biosensor performance which is described by three-dimensional molecular interactions with the membrane surface and two-dimensional molecular interactions within the tethered bilayer.

Biosensing Techniques↗