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Biomedical subjects

G Yin

Publications and source records attributed to G Yin.

48 records · Page 3Linked to original sources

[Study on influence degree of probability of endemic factors for schistosomiasis transmission in Yunnan mountainous regions].

In Zhonghe Village of Weishan County, Yunnan Province, a schistosomiasis endemic area of mountainous valley subtype, an epidemiological investigation was conducted on its natural, biological and social factors influencing schistosomiasis transmission in 1987-1990. The results were analyzed by stratified sampling analysis and probability accumulation method. It was demonstrated that 12 of 29 factors were the most important factors influencing schistosomiasis transmission including annual average air-temperature, number of infection sources, number of spots with infected snails, water temperature and annual average rainfall, etc. The values of influence degree before and after intervention measures were 3.513 and 2.066, respectively, the decrease being 41%.

Animals↗

[Detection of anti-BB antibodies in human sera by VIDAS system].

Lyme disease is an infectious disease just known in the latest decade. The sera of people from various origins were detected for Anti-BB antibodies (IgM+IgG) by VIDAS system. The results are as follows: Of 83 sera from the health-cared people, 8 were positive (9.6%); of 20 sera from the patients clinical diagnosed as tuberculosis, none was positive; of 46 sera from the patients clinical diagnosed or suspected as node diseases, 4 were positive (8.7%); of 57 sera from the patients with various ophthalmologic diseases, 13 were positive (22.8%); of 15 sera from the patients with stomatologic diseases, 4 were positive (26.7%); of 17 sera from the patients with various diseases including dermomyositis, liver and spleen swelling, undefined febrile diseases; lung cancer, lung shadow, etc.), 2 were positive (11.8%); of 16 sera from the people highly suspected with lyme disease living in the epidemic areas of Xin Jiang and Hei Long Jiang provinces, 12 were positive (75%). The same 165 sera samples were detected at the same time by VIDAS System and IFA, 24 were positive by VIDAS System (14.5%), and 131 positive by IFA (79%), the accordance rate was only 32.7%.

Antibodies, Bacterial↗

[A study on the degradation kinetics of nicotinamide powder].

The effect of temperature and humidity on the degradation of nicotinamide powder was studied below the critical relative humidity at temperatures 50-80 degrees C and relative humidities 50-80%. The rate equation of the degradation of nicotinamide under isothermal and constant humidity conditions is -dC/dt=k(Co-C)-1, where k is the apparent rate constant of degradation, Co and C are initial concentration and concentration at time t of nicotinamide, respectively. The relationship between the apparent rate constant of degradation and relative humidity RH is in K=a + m (RH), where a and m are constants. When RH are 50.35, 66.85, 75.33 and 80.35%, the apparent activation energies of degradation from Arrhenius equation are 219.94, 181.86, 168.99 and 153.89 kJ/mol, respectively. The rate equation the photodegradation of nicotinamide under room temperature is -dR/dt=K' (Ro-R)-1, where K' is the apparent rate constant of photodegradation, Ro and R are initial reflectance and reflectance at time t of nicotinamide, respectively.

Humidity↗

Extended Kalman filter (EKF) application in vitamin C two-step fermentation process.

Based on kinetic model study of vitamin C two-step fermentation, the extended Kalman filter (EKF) theory is conducted for studying the process which is disturbed by white noise to some extent caused by the model, the fermentation system and operation fluctuation. EKF shows that calculated results from estimated process parameters agree with the experimental results considerably better than model prediction without using estimated parameters. Parameter analysis gives a better understanding of the kinetics and provides a basis for state estimation and state prediction.

Ascorbic Acid↗

Studies on kinetic model of vitamin C two-step fermentation process.

This paper aims at analyzing the bioconversion process from L-sorbose to 2-Keto-L-gulonic acid with the aid of the growth factor assumption. Fermentation mechanism is discussed after making necessary simplifications. A model is established for this second step fermentation process. Nonlinear optimization together with Runge-Kutta method, are used to obtain model parameters. Results of computer simulation agree with experimental data to show the reliability of the kinetic model.

Ascorbic Acid↗

[Study of the mechanistic model for substrate-enzyme interaction on rabbit thymus tissue-based biosensor].

The authors studied the possible mechanistic model for substrate-enzyme interaction on rabbit thymus tissue-based biosensor by tissue chemistry and potentiometric method. The results show that cell construction of coarsely ground and immobilized fresh rabbit thymus is mostly intact. The channels of lipid double-molecule in the cell membranes were expanded. This tissue sensing membrane is better than the natural tissue membrane in terms of electrode response. The membrane has been found to be usable for up to 25 days with a response time of 8 minutes and slope of 51.2mV/decade. The authors suggested a new idea of "frame" construction.

Animals↗

[Preparation of a new tissue-based biosensor].

A new adenosine electrode using rabbit thymus tissue as catalyst is described. The tissue membrane was immobilized at the surface of an ammonia gassensing electrode for determination of adenosine in body fluid or tissue samples. This tissue-based biosensor showed excellent selectivity, and sensitivity, with a response slope of 51.2mV/decade, linear range of 3.16 x 10(-5)-5.62 x 10(-3) mol/L, coefficients of variation ranging from 1% to 5.72% (n = 7, m = 5), recoveries of adenosine in rabbit blood from 94.9% to 108.4% (n = 5, m = 5), and response time of 7 min. The life-time of the electrode was 25 days and 14 analogous compounds showed no significant interference.

Adenosine↗

[Growth regularities of yujin (Curcuma longa L.)].

Based on the characteristics of leaf, root and tuber growth as well as dry matter accumulation, the ontogeny of Yujin is divided into 4 stages. The growth and correlation among the leaf, root and tuber as well as accumulation of essential oils and curcumins have also been studied.

Curcumin↗

[Study on the coated carbon PVC membrane selective electrode of aconitine].

Coated carbon PVC membrane selective electrode of aconitine was prepared with the Aconitine-tetraphenylborate ion-associate complex as the electroactive material. The electrode showed a linear response to aconitine within the concentration range 1.0 x 10(-2) - 5.0 x 10(-5) mol/L. The limit of detection was 6.3 x 10(-6) mol/L and the slope of the electrode was 57.6 mV/decade. The authors established a basis and a method for the control of content limit of aconitine in Shen Fu Injection with this electrode.

Aconitine↗

[Life span and cercaria shedding of schistosome-infected snails in mountain region of Yunnan].

The life span and cercaria shedding of infected Oncomelania snails in a mountain region of Shitoudi village, Weishan County, Yunnan Province were observed in simulated local ecological environments. 135 infected snails were isolated for observation 3 months after exposure to miracidia in August, 1987. The snail survival rate from the day of initial cercaria shedding to next June, July, August and September was 27.4, 16.3, 13.3 and 11.9% respectively, and the average number of cercariae shed was 139.9, 29.6, 39.2 and 75 per month respectively. The average life span of infected snails was 171.6 days. The average number of cercariae shed per snail in its whole life was 673.0. It was estimated that the average patent period of infected snails was over half a year. As this is the first report in our country in respect to the life span and cercariae shedding of infected snails in a mountain region, the result might be useful for quantitative analysis of epidemiological factors of schistosomiasis in this kind of endemic areas as well as for formulation of control strategy.

Animals↗