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Biomedical subjects

G Z Shi

Publications and source records attributed to G Z Shi.

6 recordsLinked to original sources
PubMed2000

[99mTc-ECD SPECT CBF-quantification and its clinical significance].

OBJECTIVE: To establish a quantitative method of non-blood withdrawn with 99mTc-ECD SPECT for measuring cerebral blood flow (CBF). METHOD: Combining three compartment models and technology of the best parameters by computer with 99mTc-ECD SPECT to quantitate CBF and regional cerebral blood flow (rCBF) in control group and patient group. RESULTS: The CBFs of the control group (8 cases) and the patient group (16 cases) were (57.16 +/- 4.21) ml.min-1/100 g and (38.80 +/- 8.21) ml.min-1/100 g, respectively. The CBF and rCBF were significantly lower in patient group than those in control group (P < 0.05). CONCLUSION: The method is simple and more convenient for quantification of CBF in patients with brain disorders, and it may increase the diagnostic sensitivity and the accuracy of focus location. It is suggested that the method is accurate and reliable.

Adolescent↗
PubMed1994

[Comprehensive treatment for diabetes limb gangrene].

Anisodamine was used to improve general circulation and the microcirculation of affected limbs. Measures like local debridement, dressing change, and control of diabetes were applied in 351 patients with diabetic limb gangrene. Of the 351 patients, 301 (85.7%) were cured, 27(7.7%) were improved, 7(2.0%) failed, 6(1.7%) had limb amputated, and 10(2.9%) died. In the treatment, the nail-fold microcirculation was markedly improved. Doppler scan showed increased width and bloodflow of the vessels of the affected limbs. The criteria for the classification and diagnosis of diabetes limb gangrene are suggested.

Adult↗
PubMed1992

[Blockage of glyrrhiza uralensis and chelidonium majus in MNNG induced cancer and mutagenesis].

Glyrrhiza Uralensis (GU) and Chelidonium Majus (CM) are two kinds of Chinese herbal medicine. GU and CM not only exert much stronger effects in blocking mutagenesis due to strains of Salmonella typhimurium (TA 97, TA 98, TA 100, TA 102), but also have different degrees of obstructing mutagenesis induced by Furapromidum (F30066), Zhengdingmycin Hydrochloride (DM), N-methyl-N1-nitro-N-nitrosoguanidine (MNNG) and Methyl-methanesulfonate (MMS). The blockage effect of GU and CM obviously depends on the doses used. GU and CM could also impede the occurrence of stomach cancer induced by MNNG, and the impeding rate is about sixty percent.

Aflatoxin B1↗
PubMed1992

[Fungi N-nitrosamines and mutagens in the extract of the sour corn-soybean cakes from high incidence area of stomach cancer].

Sour corn-soybean cake is the main food of the inhabitants in high incidence area of stomach cancer in Linqu county Shandong province. In the extract of the sour corn-soybean cakes, twelve mycotoxin-producing fungi and 3 N-nitrosamines (NDMA, NDEA, NMEA) were detected and the finding rates of the fungi and the N-nitrosamines were 93.3% and 92.3%, respectively; the concentration of NDMA was 0.4-3.8 ng/ml, NDEA 0.2-8.1 ng/ml, and NMEA 0.3-1.4 ng/ml. The positivity rate of the Ames test (most positive materials were direct mutagens) was 44.12%. The experimental results showed that the extract of the sour corn-soybean cakes containing carcinogenic and mutagenic subjects could have some causal relationship with the incidence of stomach cancer.

Food Microbiology↗