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Biomedical subjects

G Zafiropoulos

Publications and source records attributed to G Zafiropoulos.

7 recordsLinked to original sources
PubMed1995

An intramedullary aligned bone cutting jig for elbow replacement.

One of the main post operative complications of total elbow replacement has been dislocation and fracture of the olecranon. This has been associated with rotational malalignment of the bone cuts of the proximal ulna caused by the current free hand cutting method. This paper presents an intramedullary aligned bone cutting jig which gives rotational location on the ulna for the bone cuts, without notching the olecranon.

Biomedical Engineering↗
PubMed1992

Gingival health and salivary function in head and neck-irradiated patients. A five-year follow-up.

Gingival health and salivary gland function were evaluated for a period of 5 years in 14 patients who received head and neck irradiation for nasopharyngeal carcinoma (seven patients; total dose greater than 60 Gy, nasopharyngeal field) and Hodgkin's lymphoma (seven patients; total dose less than 50 Gy, "mantle" field). Plaque index (PII), bleeding index (BI), gingival recession (GR), whole saliva flow rate (WSFR), left parotid sialographic morphology, and salivary gland radioisotopic activity were assessed immediately before radiotherapy and annually thereafter. The nasopharyngeal group had perfect correlation between postradiation depression of WSFR and the sialographic and scintigraphic scores (R = -1.00 and -0.96, respectively). The degree of gland dysfunction correlated negatively with BI and the BI/PII ratio (r = -0.497) and with GR (r = 0.681). The same correlations were noted in the group with Hodgkin's lymphoma during the first 3 years of follow-up. However, recovery of parotid gland function (WSFR and scintigraphic scores) and morphology (sialographic scores) and return to the preradiation relation between WSFR and both BI/PII ratio (r = 0.75) and GR (r = -0.71) were noted in the fourth year. The differences between the nasopharyngeal and Hodgkin's lymphoma groups are attributable to the delineation of the radiation field employed in each group.

Adult↗
PubMed1990

Periodontal alterations in patients with pemphigus vulgaris taking steroids. A biannual assessment.

Periodontal health parameters and salivary cortisol were studied in 19 adult pemphigus vulgaris patients on chronic steroid therapy. The patient population was divided into non-medicated and medicated subjects at intake into the study. A significant difference between the 2 examinations, performed at an interval of 8.73 months +/- 4.35, was found in bleeding index (p less than 0.000 and p less than 0.04, respectively) and gingival recession (p less than 0.000 and p less than 0.009) in both groups. No changes occurred in alveolar bone height. Steroid therapy altered the bleeding index (R = 0.60 and R = 0.80) and gingival recession (R = 0.87 and 0.91) in a dose-related manner, and induced low salivary cortisol. The findings of this study would suggest suppression of the host inflammatory reaction, resulting in an alleged healthy clinical appearance of the periodontium.

Adolescent↗
PubMedDate not supplied

Fixation strength of the ulnar component of total elbow replacement.

After clinical failure of ulnar component fixation by olecranon fracture occurred, this study examined different component designs to find the strongest type. Components requiring square cuts or rounded cuts to prepare the proximal ulna with short or long stems of polyethylene or metal were implanted in paired cadaver bones and tested to failure. Loads were applied through the articular surface in an anterior-posterior direction, causing bending fracture of the olecranon. The main findings were a higher strength if the bone was prepared to take a rounded rather than a square-shaped prosthesis body, a slightly higher strength with a metal component compared with a similarly shaped polyethylene component, and slightly less strength if a longer stem was used. We recommend the use of a polyethylene component with a rounded shape and short stem, because it will be thinner, entailing less bone excavation. Additionally, it is less costly than a metal-backed design.

Aged↗