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Biomedical subjects

G Zierott

Publications and source records attributed to G Zierott.

At least 19 recordsLinked to original sources
PubMed1979

[Clinical classification of the severity of lung injuries (author's transl)].

The observations made in 651 cases of traumatic lung injuries suggested the advisability of dividing these injuries into three groups according to the severity of the clinical picture. The criterion was the degree of impairment of respiratory function as assessed by repeated gas analyses. By relating function to severity of the clinical picture it was possible not only to institute the appropriate therapeutic measures but also to obtain information regarding the prognosis. Lung injuries in group 2 and 3 require prompt transfer to an intensive care unit with experience in chest surgery before irreversible damage has set in.

Blood Gas Analysis↗
PubMed1979

[Residual lesions after serial fracture of ribs (author's transl)].

Follow-up examinations at regular intervals to recognize trauma-induced lesions are as essential for persons who have suffered a chest trauma as they are for cases of injury to the limbs. A classification into three groups according to the number of broken ribs relates satisfactorily with thoraco-pulmonary complications and residual damage. Injuries in group 1 leave practically no permanent damage; in group 2 they are apt to be followed by residual respiratory impairment while in group 3 the likelihood of permanent impairment of lung function is very high. Spirometry, roentgenography and fluoroscopy, and lung scanning are of special diagnostic value in assessing late sequelae of multiple rib fractures. Gas analyses are of little value. They would provide more accurate information if performed during exercise under standard conditions.

Adult↗
PubMed1976

[Postoperative changes in immunoglobulin-concentrations after splenectomy. A prospective survey series (author's transl)].

The three immunoglobulin classes A, G and M were quantitatively determined through immune diffusion preoperatively as well as in the first 60 days in 31 patients after splenectomy and the results were statistically evaluated. In comparison with the initial preoperative values, a temporary, significant elevation of the serum concentration of the IgA and IgG was found, whereby the IgA concentration on the 60th postoperative day corresponded already to the preoperative initial values, whilst the IgG were at this time still significantly elevated. There was a beginning significant decrease in serum concentration of the IgM between the 15th and 20th postoperative day, which was very pronounced on the 60th day. This determination coincides with the half-life time of the IgM and can be regarded as an indication for a localisation of the IgM producing cells in the spleen.

Female↗
PubMed1976

[Diagnostical and therapeutical aspects of post-traumatical endobronchial bleeding (author's transl)].

Post-traumatic endobronchial bleeding is a serious concomitant injury in thoracic traumas. Untreated cases are threatened early with pulmonary insufficiency caused by the displacement of a blood clot with in the respiratory tract. Pathophysiology, diagnosis and treatment of the post-traumatic endobronchial bleeding are discussed. Conservative and surgical measures are discussed on the basis of 15 observations. The prognosis of the endobronchial bleeding depends decisevly on the length of its existence and intensity. Conservative or operative procedure should be decided on the basis of repeated endoscopical controls. A liberal attitude towards the operative therapy is recomended.

Adult↗
PubMed1975

[A case of Behcet's disease with multiple intestinal ulcerations(author's transl)].

A case is reported of Behçet's disease in a 41-year-old man, in the course of which colitis with perforation developed over two years, with fatal results. This is a rare complication of Behcet's disease and must be differentiated from ulcerative colitis and Crohn's disease. Blood transfusions have a limited therapeutic value in the terminal phase of the disease, which among others is characterized by a generalized depression of response of peripheral lymphocytes to stimulation.

Adult↗
PubMed1975

[Quantitative bacteriological evaluation of intraoperative peritoneal lavage in animal experiment].

In a model experiment with albino rats the effectiveness of intraoperative peritoneal lavage has been tested by means of defined lethal staphylococus aureus infections. A positive result can only be expected, if intraperitoneal lavage is started immediately after bacterial contamination. In this can a 10% decrease in the total number of germs be expected. If the lavage is done up to 15 or 30 min after the germ application the efficiency rate declines to less than 1%. In addition bacteraemia could be proved already 15 min after germ application. These results clearly show the limits of peritoneal lavage with physiological saline.

Animals↗
PubMed1975

[Blood, urine and bile levels of ampicillin during continuous intravenous infusion].

During and after continuous i.v. infusion of 0.25 g ampicillin (Binotal-R) per hour, serum and urine concentrations were determined in 6 healthy adults (volunteers) and in 12 geriatric patients with normal liver and kidney function. In old persons serum levels were higher and after the end of infusion decreased more slowly than in young adults. These data may be explained by a lower capillary permeability and renal clearance in older people. In patients with T-tube drainage after cholecystectomy, bile levels of ampicillin (during i.v. continuous infusion of 0.25 g/h) were equal to double those in serum. Recovery from the file was calculated as 0.1-0.2 percent.

Adult↗
PubMed1975

[Local postoperative complications after surgery of the cardia].

602 patients had an operation on the cardia of stomach during 10-year period 1964-1973 in the Surgical Department of Kiel University. In total there were 395 operations without resection with a 9% postoperative complication rate opposite to 207 resections of the cardia with 38% complications. Here the primary lethality was 7% (14 patients). The complications of suture insufficiency and hemorrhage are demonstrated and their outcome checked up: 13 of 16 patients died of suture insufficiency (81%) and 8 of those 13 with hemorrhage (62%). Especially important for the successful treatment of suture insufficiency are early diagnosis, drainage of the area and closure of the leakage. A new technique of suture insufficiency treatment is reported: T-Drainage into the leakage. This has led to a lowering of the death rate.

Cardia↗