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G Zoulek

Publications and source records attributed to G Zoulek.

28 records · Page 2Linked to original sources
PubMed1984

[Hepatitis B and the delta agent].

The delta agent seems to be a defective RNA virus which is dependent on a helper function provided by hepatitis B-virus. Delta agent infection occurs by parenteral transmission either together with hepatitis B-virus, or superimposed on chronic HBV infection. In the first case biphasic hepatitis may result, whereas in the second case mostly an acute delta agent infection develops, which is often followed by chronic delta hepatitis. The delta agent is endemic to certain areas, and also in certain risk groups such as drug addicts, hemophiliacs and polytransfused patients. A delta agent infection should be suspected in case of acute hepatitis in a hitherto clinical inapparent chronic carrier, especially if he belongs to one of the above mentioned risk groups. There is no specific therapy for delta infection, the only prophylactic measure is vaccination against hepatitis B.

Carrier State↗
PubMed1984

Evaluation of a reduced dose of hepatitis B vaccine administered intradermally.

Intradermal inoculation of hepatitis B vaccine (HBsAg subtype adw) caused no side effects, but the vaccine was less immunogenic than following intramuscular administration. Intradermal inoculation does not, therefore, offer a major advantage to the generally used intramuscular immunization. A single multisite intradermal administration of a reduced dose of vaccine did not result in a more rapid seroconversion compared to intramuscular inoculation. Although the antibody levels were similar after two intradermal or intradermal or intramuscular injections given 1 month apart, the booster (third injection) at 6 months resulted in anti-HBs levels that were about 10 times higher following intramuscular inoculation as compared to intradermal. All persons immunized developed anti-HBs. The levels of anti-HBs (a and w) were about 30-40% of the total anti-HBs, and the proportion did not change significantly during the course of immunization. Cross-protection against all HBV strains is thus also assured after intradermal administration of vaccine containing only one HBsAg subtype (adw). A skin reaction was elicited only in a small proportion of anti-HBs-positive individuals, and the reaction correlated roughly with the immune responses.

Adult↗
PubMed1979

Hyperdibasicaminoaciduria in a Turkish infant without evident protein intolerance.

The first patient of Turkish descent with hyperdibasicaminoaciduria is described. Recurrent diarrhea was observed only during the first three months of life. The infant exhibited low plasma levels of ornithine and arginine. Intestinal absorption of lysine was decreased. Hyperammonemia was noticed only after an i.v. alanine load. It was prevented by addition of arginine.

Arginine↗
PubMedDate not supplied

Mycotic keratitis in Paraguay.

Patients with corneal ulcer, residing mainly in rural areas of Paraguay, were controlled for mycotic eye infections. In 26 cases out of 45 (58%) presence of filamentous fungi was observed (Fusarium sp. (11), Aspergillus sp. (5), Cladosporium sp. (3), Alternaria sp. (2), Acremonium sp. (1), Curvularia sp. (1), culture negative (3)). In 17 cases also pathogenic bacteria were present. Most of the patients were farmers and belonged to the low income class. These data indicate that mycotic keratitis may be a frequent cause for eye infections in developing countries.

Adolescent↗