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Biomedical subjects

G de Candussio

Publications and source records attributed to G de Candussio.

6 recordsLinked to original sources
PubMed1975

[Pediatric spirometry as a prognostic test of adult obstructive bronchopneumopathy].

Authors study the spirometry of 40 asthmatic children between 6 and 12 years in age. Spirometric determination was performed immediately after the asthmatic attack and also at least 15 days after the last attack. The cases have been subdivided into four groups for what concerns Tiffeneau's index and Mottly's index. The group of subjects with abnormal Tiffeneau's and Mottly's indices is of particular interest. There exists probably in such subjects a beginning emphysema that might lead up, at the adult age, to a picture of obstructive bronchopneumopathy.

Asthma↗
PubMedDate not supplied

The effects of air pollution on the respiratory health of children: a cross-sectional study.

To investigate the effects of air pollution on the respiratory health of children, a subject of some controversy, a comparative study was undertaken of 2,385 school children who lived in central urban, peripheral urban, and suburban areas. Daily monitoring of sulphur dioxide and total suspended particle concentrations in all areas showed that pollutant concentrations in central and peripheral urban areas were above commonly accepted safety levels for respiratory health, while concentrations in the suburban area were within acceptable limits. A questionnaire administered to each mother assessed environmental exposure to pollutants in the household, the occurrence of respiratory symptoms as well as lung diseases as diagnosed by a physician, and general information. Children were interviewed about smoking habits and any acute respiratory symptoms. Children also performed standard lung function tests. Results showed that children from both urban areas had lessened pulmonary function and a higher prevalence of bronchial secretion with common colds than did those from the suburban area. These differences persisted after corrections for exposure to indoor pollutants, active or passive smoking, socioeconomic status, and sex. Parental cigarette smoking was related to a fall in forced expiratory volume in 1 second and an increased incidence of acute respiratory illnesses and chronic cough in children. Although boys had higher lung volumes and lower air flow, regression analysis showed no significant influence of the interactions "sex-geographic area" and "sex-smoking" on lung function. It was concluded that air pollution has a significant effect on the respiratory health of children.

Air Pollutants↗
PubMedDate not supplied

Changes in lung function of children after an air pollution decrease.

Forced vital capacity (FVC), forced expiratory volume in 1 sec (FEV1.0), forced expiratory flow between 25 and 75% of FVC (FEF25-75), and maximal expiratory flow at 50% of FVC (MEF50) were measured in 1,880 school children who lived in urban areas before and after a decrease of air pollution. A group of 162 children from a suburban area served as controls. In the first survey, FEV1.0, FEF25-75, and MEF50 of children from urban areas were significantly lower, while in the second survey they were not significantly different from those of controls. The slopes over time of FEV1.0, FEF25-75, and MEF50, adjusted for sex and anthropometric variables, were closely related to the decrease of pollutants concentration. Our results suggest that a decrease of air pollution may produce an improvement of lung function.

Adolescent↗