Biomedical subjects

Gamze Aren

Publications and source records attributed to Gamze Aren.

9 recordsLinked to original sources

PubMed2005

Clinical performance of sealants with and without a bonding agent.

OBJECTIVES: The objective of this study was to assess the effect of a one-bottle bonding agent on sealant success after 3, 6, 12, and 24 months. METHOD AND MATERIALS: The sample group consisted of 30 schoolchildren (8 to 10 years of age) who had all their permanent first molars sound and unsealed. Occlusal sealants were placed on first molars according to a split-mouth design. Sealant scoring occurred at 3, 6, 12, and 24 months and was performed by two clinicians blinded to the treatment group. Fisher's exact test was used to analyze the data. RESULTS: The clinically acceptable marginal integrity rates for sealants with a bonding agent after 3, 6, 12, and 24 months were 93%, 93%, 83%, and 79%, respectively. For sealants without a bonding agent, the clinically acceptable marginal integrity rates after 3, 6, 12, and 24 months were 90%, 88%, 81%, and 77%. The rates for no color change in sealants with a bonding agent after 3, 6, 12, and 24 months were 96%, 93%, 81%, and 75%, respectively. For sealants without a bonding agent, the no color change rates after 3, 6, 12, and 24 months were 93%, 93%, 79%, and 72%. After 24 months, 73% of the sample group were available for recall. The retention rates for sealants with and without a bonding agent after 24 months were 79% and 75%, respectively. The results of the statistical analysis showed that there were no differences among the sealants with and without bonding agents evaluated in relation to marginal integrity, marginal discoloration, and anatomic form. CONCLUSION: The success of a sealant is related to whether the sealant is applied under optimal conditions. The results of this study show that at the 2-year mark, the placement of a bonding agent under sealants did not significantly affect the clinical success of sealants.

Child↗

PubMed2005

Reasons for early loss of primary molars.

PURPOSE: The aims of this study were to investigate the principal reasons for untimely loss of primary molars and to evaluate the risk factors of early primary molar loss in children aged four to nine years. MATERIALS AND METHODS: 1150 untimely lost primary molars were analyzed from 546 patients. The early loss of primary molars was analyzed in relation to age, sex, dmf (t), DMF (T) scores, toothbrushing frequency, history of treatment and maternal education. The data were converted to SPSS format. Pearson Chi-square test was used for statistical analysis. RESULTS: Among the investigated subjects, 15.2% of children reported regular toothbrushing. Only 23.1% of subjects had a history of treatment before the tooth extraction and 33% of mothers had a low education level. Untimely loss of primary molars due to pain, caries and sepsis were 30.2%, 31% and 38.8%, respectively. The frequency of 'only one primary molar loss' was significantly higher in group 1 (p < 0.05), however the frequency of 'more than one primary molar loss' for group 2 was more than group 1 (p < 0.05). Irregular toothbrushing for the children in group 2 was found significantly high than in group 1 (p < 0.05). Irregular toothbrushing was associated with number of early primary molar loss in group 2 (p < 0.05). The level of maternal education was associated with dmf (t) scores (p < 0.05). The caries incidence was associated with number of early primary molar loss in both groups (p < 0.05). The mean number of treated teeth before extraction for group 2 was significantly higher than for group 1 (p < 0.05). CONCLUSION: Results of this study suggested that irregular toothbrushing, high dmf (t) scores and untreatment of carious primary molars were significant risk factors in early loss of primary molars. Every effort must be taken into account in restoring rather than extracting carious teeth.

Chi-Square Distribution↗

PubMed2003

Evaluation of oral and systemic manifestations in an amelogenesis imperfecta population.

OBJECTIVES: The aim of this investigation was to describe the dental and craniofacial characteristics of patients with amelogenesis imperfecta (AI). METHODS: The study group included 43 patients(33 female and 10 male) with a mean age of 11.4+/-2.6 years. A panoramic and a cephalometric radiograph were obtained from each of these patients. Clinically AI cases were divided into four main groups according to Witkop. All patients were evaluated for chronological, bone and dental age. The patients who had severe retarded bone age were evaluated for plasma growth hormone(GH) concentrations. RESULTS: Dental and bone ages were retarded with respect to chronological age in five patients. Dental maturity and tooth eruption were not age- appropriate in some of our patients. In type III AI patients a delay in skeletal age was observed. Severe late eruption was seen in 3 patients, severe delay in dental maturity was noted in patients with type IV AI. Dental age was clinically lower in GH-deficient subjects, and skeletal age was consistently more retarded than dental age when compared to chronological age. Anterior open bite was present in both primary and permanent dentitions of 50% of the patients with type I AI, 30.8% of the patients with type II AI, and 60% of type III AI. CONCLUSION: It is concluded that the primary structure for the classification of AI be based on the mode of inheritance, with the clinical and radiographic appearances (and any other features such as systemic findings) being the secondary discriminators.

Age Determination by Skeleton↗

PubMed2003

Periodontal health, salivary status, and metabolic control in children with type 1 diabetes mellitus.

BACKGROUND: The aim of this study was to determine whether detectable periodontal destruction and alterations in the salivary status were present with duration of diabetes in children with type 1 insulin-dependent diabetes mellitus (type 1 DM) as compared to healthy controls. METHODS: Sixteen newly diagnosed children with DM (group 1), 16 children with type 1 DM of long duration (group 2), and 16 healthy children (group 3) participated in the study. Periodontal health was assessed by plaque index, gingival index, bleeding on probing, and periodontal probing depths. The flow rate, pH, buffering capacity, and peroxidase activities of stimulated saliva were determined. The data were analyzed by Kruskall-Wallis, Student t test, and Pearson's correlation analysis. RESULTS: The mean values for fasting blood glucose levels for the diabetic groups were significantly higher than for the controls. The mean values for salivary buffering capacities and salivary pH from the diabetic groups were significantly lower than for the controls. The plaque index values for the diabetic groups were significantly higher than for the controls. The mean gingival index value for group 1 was significantly lower than for group 2. The mean periodontal probing depths for group 1 were similar to those of the non-DM controls, but the mean periodontal probing depths for group 2 were significantly greater than for both the non-DM controls and group 1. Group 1 had significantly greater bleeding on probing scores than did the other groups (P < 0.05). CONCLUSION: The glycemic status of the diabetic subjects affects the periodontal probing depths, salivary pH, buffering capacity, and peroxidase activity.

Blood Glucose↗

PubMed2003

Freeman-Sheldon syndrome: a case report.

Freeman-Sheldon syndrome, also called "whistling-face syndrome," is a very rare genetic condition, occurring both sporadically and by transmission through autosomal dominant or recessive mode, which affects primarily the face and skeleton. Characteristics include microstomia of the mouth, which gives the person a whistling appearance, a flat face, club feet, contracted joint muscles of the fingers and hands, and underdeveloped nose cartilage. This article describes a case of Freeman-Sheldon syndrome in a 10-year-old male. The most apparent deformities are associated with orofacial and skeletal development.

Abnormalities, Multiple↗

PubMed2003

In vitro effects of bleaching agents on FM3A cell line.

OBJECTIVE: There are concerns about the possible pathologic effects of relatively long-term exposure of oral tissues to bleaching agents. The purpose of the present study was to investigate the cytotoxic effects of various bleaching agents on mouse mammary carcinoma FM3A cell line. METHOD AND MATERIALS: FM3A cell line obtained from European Collection of Animal Cell Cultures was used in cell culture assay. Exponentially growing cells were seeded in 1 x 105 cells/mL in 5 mL of RPMI 1640 medium supplemented with 10% fetal calf serum and antibiotics in each well of a six-well plate. PowerGel was applied onto the cell culture medium and incubated for 24 hours at 37 degrees C in a 5% carbon dioxide atmosphere after light curing. Opalescence PF gel was left on cell culture medium for 24 hours at the same conditions. After 24-hour incubation, the cells were collected by trypsinization and counted with a hemocytometer. For cell viability, trypane blue exclusion assay was used. The cytotoxicity of PowerGel and Opalescence PF were determined by evaluation of cell growth and viability in comparison to untreated controls (cell growth = 100%). The data were submitted to statistical analysis (One-way analysis of variance, Dunnett's t test). RESULTS: Cell growth after 24 hours was significantly reduced (P = .000) in comparison to the control group. The cell growth in the Opalescence PF gel group also was reduced (P < .05). It was found that both gels affected cell viability. CONCLUSION: PowerGel and Opalescence PF showed a cytotoxic effect on cell growth in FM3A cell line.

Analysis of Variance↗

PubMed2002

Congenital analgia syndrome.

Hereditary sensory and autonomic neuropathy is a rare syndrome which is seen in early childhood. Five different types have been described. Absence of pain and self-mutilation are characteristic findings of this syndrome. This report describes one female and two male children with the syndrome. The most severe oral consequence of their disorder was damage to the oral tissues and tongue. The primary aim in management was to monitor the eruption of the permanent teeth.

Journal Article↗

PubMedDate not supplied

Inverted impaction of primary incisors: a case report.

Dental and radiological findings of a 5-year-old female patient show inverted impaction of the maxillary primary incisors. Family and personal histories of the patient were unremarkable. There were no abnormalities in general growth and development nor was there any history of trauma.

Child, Preschool↗

PubMedDate not supplied

Clinical and immunological findings of two siblings in a family with generalized aggressive periodontitis.

PURPOSE: The clinical and immunological data from 2 siblings with generalized aggressive periodontitis in a family are presented. METHODS: Peripheral blood lymphocyte subpopulations were analyzed by dual color flow cytometry by using monoclonal antibodies for the lymphocyte receptors CD2, CD3, CD4, CD5, CD8, CD16, CD19, CD11b, CD11c, and HLA-DR. RESULTS: Both patients showed a higher increase in CD11b/CD18 expression. CONCLUSIONS: The evaluation of CD11b and CD11c receptors may be important in explaining leukocyte abnormalities in the pathogenesis of the disease. One of the patients showed decreased counts of natural killer cells while the other was normal. In both patients, the authors observed a slight elevation in Ts lymphocytes.

Antigens, CD19↗