Biomedical subjects

Gary D Fleischer

Publications and source records attributed to Gary D Fleischer.

3 recordsLinked to original sources

PubMed2004

New operative method for fundal variceal bleeding: fundectomy with periesophagogastric devascularization.

Cirrhotic patients with gastric fundal bleeding occasionally require operative intervention. Fundal variceal bleeding may be controlled by performing a fundectomy in addition to periesophagogastric devascularization. For 23 patients with cirrhosis, preoperative nonsurgical intervention alone could not achieve definitive control of variceal bleeding from the gastric fundus, and periesophagogastric devascularization with the fundectomy--specifically resection of the varix-bearing lesion in the fundus--was performed. Direct inspection and palpation determined the area for the fundectomy, and resection was limited to the engorged varix-bearing area. The overall mortality rate was 26.1%. There were two postoperative deaths (18.2%) among 11 patients in the elective operation group and four deaths (33.3%) among 12 patients in the emergency operation group ( p > 0.05). The mortality rates among class A, B, and C patients, following the Child-Pugh classification for hepatic functional reserve, were 0% (0/4), 23.1% (3/13), and 50.0% (3/6), respectively ( p > 0.05). The patients who died had been transfused preoperatively with a mean of 13.0 +/- 10.5 units, and those who survived received a mean of 6.00 +/- 5.96 units ( p > 0.05). Patients who were successfully stabilized by preoperative endoscopic intervention had significantly lower mortality ( p < 0.001). During follow-up there was no recurrent bleeding from gastric varices, and there was only one case (4.35%) of hemorrhage from esophageal varices. Hence, periesophagogastric devascularization and fundectomy offers an alternative operative method for cirrhotic patients with variceal hemorrhaging from the gastric fundus.

Adult↗

PubMed2003

Hand-assisted laparoscopic total gastrectomy.

Although the standard method to manage gastric cancer is still radical gastrectomy, minimally invasive surgery is of great interest in early gastric cancer because of its potential impact on improving the quality of life, if the disease is curable. With its degree of technical difficulty, laparoscopic total gastrectomy has not yet met with widespread acceptance. However, using a hand-access device, a total gastrectomy and Roux-en-Y esophagojejunostomy with a D1 plus alpha lymph node dissection and omentectomy with an Ultrashear was performed in its entirety. The operation took 6 hours, and the blood loss was 500 mL. The patient recovered uneventfully and was discharged on the 16th postoperative day. In terms of recovery and quality of life, laparoscopic total gastrectomy is a technically feasible and reasonable option for the management of early gastric cancer in the proximal stomach, especially when an endoscopic mucosal resection is not indicated.

Adenocarcinoma↗

PubMed2003

Laparoscopy-assisted D2 subtotal gastrectomy in early gastric cancer.

The purpose of this study is to prove the safety and efficacy of laparoscopy-assisted subtotal gastrectomy and D2 lymph node dissection using 4 ports and an EEA stapler with a Billroth I anastomosis. From 1999 to 2001, 20 patients with EGC located in the distal stomach underwent laparoscopy-assisted Billroth I gastrectomy (LABIG). A 4-port-technique was performed for omentectomy, vascular ligation, and D2 lymph node dissection. A mini-incision was created between the two ports in the epigastric area and a gastroduodenal anastomosis with an EEA stapler and a distal resection was performed. The mean operating time was 261.8 (170-410) minutes. There was one postoperative complication without any intraoperative transfusions or perioperative mortality. The number of harvested nodes was 31.9 +/- 11.4. Mean distance from the lesion to the margin of resection was 5.3 +/- 2.2 cm proximally and 4.0 +/- 2.0 cm distally. On average, oral liquids were started at the 4.7th (3rd-8th) postoperative day. LABIG is a safe and effective way of performing D2 gastrectomy in terms of morbidity and oncological principles. A randomized controlled clinical study to compare long-term survival and quality of life is warranted.

Abdomen↗