Biomedical subjects

Gary J Sharman

Publications and source records attributed to Gary J Sharman.

4 recordsLinked to original sources

PubMed2006

Java applets for viewing one- and two-dimensional NMR spectra.

Two Java applets, which allow viewing and simple reprocessing operations of one- and two-dimensional NMR spectra from within a web page, are described. For the 1D viewer, phasing, integration, peak picking and referencing are supported. Bruker, Varian and JCAMP-DX processed data files can be opened. The 2D viewer allows f2 phasing and referencing, and can read native Bruker processed data. The compiled applets are available from the author on request.

Magnetic Resonance Spectroscopy↗

PubMed2005

1H and 13C NMR data to aid the identification and quantification of residual solvents by NMR spectroscopy.

We present reference data and a javascript web page which allow the rapid identification and quantification of residual solvents by NMR. The data encompass all of the ICH-prescribed solvents and were obtained for a number of NMR solvents. We also present an example of its application.

Carbon Isotopes↗

PubMed2004

The measurement of high enantiomeric excesses in chiral liquid crystals using 19F NMR and exchangeable protons in 2H NMR.

It is shown that the 19F spectrum and the 2H NMR spectrum of deuterated protons in a chiral liquid crystal medium can be used to measure high enantiomeric excesses.

Journal Article↗

PubMed2004

Automated structure elucidation of two unexpected products in a reaction of an alpha,beta-unsaturated pyruvate.

The reaction between an alpha,beta-unsaturated pyruvate and ethyl diazoacetate (EDA) yielded two unexpected products. The structures of these products were determined by automated elucidation of the chemical structures using spectroscopic inputs of a series of 1D and 2D NMR data using the computer program ACD/Structure Elucidator, StrucEluc. The formation of these products is rationalised. Their structures were also confirmed by x-ray crystallography.

Acetates↗