Biomedical subjects

Geoffrey Bird

Publications and source records attributed to Geoffrey Bird.

6 recordsLinked to original sources

PubMed2006

Attention does not modulate neural responses to social stimuli in autism spectrum disorders.

We investigated whether individuals with autism spectrum disorders (ASD) would show attentional modulation for social (face) and non-social (house) stimuli. Sixteen individuals with ASD and 16 matched control participants completed a task in which pairs of face and house stimuli were present on every trial, with one of the pairs randomly assigned to attended locations and the other to unattended locations. Both mass-univariate (SPM) and region of interest analyses suggested that responses to houses were modulated by attention in both groups, but that only the control participants demonstrated attentional modulation of face-selective regions. Thus, the participants with ASD demonstrated a lack of attentional modulation which was particularly evident for the social stimulus. Analyses of effective connectivity indicated that these results were due to a failure of attention to modulate connectivity between extrastriate areas and V1. We discuss how these results may suggest a mechanism to explain the reduced salience of social stimuli in ASD.

Adult↗

PubMed2005

Action observation supports effector-dependent learning of finger movement sequences.

Practising a motor skill can result in effector-dependent learning (learning that does not transfer from the set of muscles used in training to a new set of muscles). Proceeding from neurophysiological evidence of motor activation during action observation, this study asked whether observational learning, learning through observation of skilled performance, can also be effector-dependent. Adult human participants observed a model's right hand as the model responded to an eight-item sequence in a serial reaction time (SRT) task. Their sequence learning was then compared in two tests with that of controls who had observed the model's right hand responding to random targets during training. All participants performed the SRT task with their right hand in the first test and with their left hand in the second. Evidence of observational learning was obtained in the right hand test but not in the left hand test. This implies that sequence learning based on observation of right hand performance did not transfer to the left hand, and therefore that observational learning can support effector-dependent learning of finger movement sequences. A second experiment used the same procedure to assess learning by a group of participants who observed a sequence of response locations only. This group did not observe the model's responses. Results suggested that action observation was necessary for the effector-dependent observational learning demonstrated in Experiment 1.

Adult↗

PubMed2005

Experience modulates automatic imitation.

Action observation gives rise to activation in corresponding areas of the premotor and primary motor cortices. We tested the hypothesis that this activation depends on visual-motor connections established through correlated experience of observing and executing the same action. Previous work has shown that hand opening and hand closing gestures are facilitated when subjects observe the movement they are performing, relative to a condition in which they observe a different movement from the one they are performing. Experiment 1 replicated this finding in a simple reaction time (RT) procedure using stimulus-response (SR) movements in orthogonal planes. This implies that the effect is an example of automatic imitation, an instruction-independent tendency to execute movements that are topologically similar to those observed, and not merely an example of spatially compatible responding. In Experiment 2, the automatic imitation effect found in Experiment 1 was abolished by a brief period of training in which subjects responded to hand opening by closing their hands, and to hand closing by opening their hands. This outcome is consistent with the hypothesis that, rather than being innate, the cortical connections mediating motor activation by action observation are formed through experience.

Adult↗

PubMed2005

Robotic movement elicits automatic imitation.

Recent behavioural and neuroimaging studies have found that observation of human movement, but not of robotic movement, gives rise to visuomotor priming. This implies that the 'mirror neuron' or 'action observation-execution matching' system in the premotor and parietal cortices is entirely unresponsive to robotic movement. The present study investigated this hypothesis using an 'automatic imitation' stimulus-response compatibility procedure. Participants were required to perform a prespecified movement (e.g. opening their hand) on presentation of a human or robotic hand in the terminal posture of a compatible movement (opened) or an incompatible movement (closed). Both the human and the robotic stimuli elicited automatic imitation; the prespecified action was initiated faster when it was cued by the compatible movement stimulus than when it was cued by the incompatible movement stimulus. However, even when the human and robotic stimuli were of comparable size, colour and brightness, the human hand had a stronger effect on performance. These results suggest that effector shape is sufficient to allow the action observation-matching system to distinguish human from robotic movement. They also indicate, as one would expect if this system develops through learning, that to varying degrees both human and robotic action can be 'simulated' by the premotor and parietal cortices.

Adult↗

PubMed2005

Effector-dependent learning by observation of a finger movement sequence.

Can observational learning be effector dependent? In 3 experiments, observers watched a model respond to a 6-item unique sequence in a serial reaction time task. Their sequence knowledge was then compared with that of controls who had performed an unrelated task or observed a model responding to random targets. Observational learning was indicated when the introduction of a new sequence was associated with more reaction time elevation in observers than in controls. The authors found evidence of observational learning only when observers used the finger movement sequence that they observed during training, not when they responded at the same sequence of locations using different digits. Free generation and recognition tests also detected observational learning. These results imply that observational learning can be both explicit and effector dependent.

Adult↗

PubMed2005

Sequence learning by action, observation and action observation.

The serial reaction time (SRT) task was used to compare learning of a complex sequence by action (participants responded to sequential stimuli), by observation (participants watched but did not respond to sequential stimuli), and by action-observation (participants watched an expert model responding to sequential stimuli). Each of these groups was compared with an untrained control group. Experiment 1 indicated that both observation and action-observation were sufficient to support learning of a 12-item second-order conditional (SOC) sequence. Experiment 2 confirmed these findings, and showed that, as indexed by reaction time (RT), the extent of learning by observation and by action-observation was comparable to that of action-based learning. Using a recognition test, Experiment 2 and 3 also provided evidence that, whereas learning by stimulus observation was explicit, learning by action-observation was implicit. These findings are consistent with a connection between motor systems and implicit learning, but do not support the hypothesis that overt action is necessary for implicit learning.

Adult↗