Biomedical subjects

George M Brinson

Publications and source records attributed to George M Brinson.

2 recordsLinked to original sources

PubMed2004

Endoscopic management of retained airgun projectiles in the paranasal sinuses.

OBJECTIVES/HYPOTHESIS: This article presents 3 cases to illustrate the appropriate management of airgun injuries with retained projectiles in the paranasal sinuses. The indications, techniques, and potential complications of removal of these foreign bodies from the paranasal sinuses are discussed. STUDY DESIGN: We conducted a case series consisting of 3 patients and a review of the literature. METHODS: Three consecutive patients who sustained airgun injuries to the face with retained bullets in the paranasal sinuses are presented. Projectiles were present in the maxillary, ethmoid, and sphenoid sinuses. The literature pertaining to this subject is reviewed. RESULTS: All retained projectiles were removed endoscopically without complications. Stereotactic guidance was used in 2 cases. CONCLUSIONS: Airgun injuries to the paranasal sinuses are relatively uncommon. Projectiles can safely be removed using endoscopic techniques in selected cases. When possible, foreign bodies in the paranasal sinuses should be removed to prevent long-term sequelae.

Accidents↗

PubMed2003

Viral otitis media.

Acute otitis media (AOM) and viral upper respiratory tract infections (URIs) represent the two most common diseases affecting the human population, and account for substantial patient morbidity and health care costs. Epidemiologic and experimental studies suggest that URIs play a causal role in the pathogenesis of AOM. Specifically, viruses can either invade the middle ear (ME) space and invoke an inflammatory response that culminates in ME effusion formation and consequent symptoms, or URIs might cause eustachian-tube dysfunction, resulting in negative ME pressures and subsequent ME effusion (hydrops ex vacuo theory). The events responsible for the inflammatory response of the human ME following viral exposure have not been well characterized. Although many prophylactic and therapeutic interventions have been evaluated for the treatment of AOM, the information on virus-specific interventions is sparse. In this article, the epidemiology, pathogenesis, diagnosis, and management of viral otitis media are reviewed.

Humans↗