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George Ostrouchov

Publications and source records attributed to George Ostrouchov.

2 recordsLinked to original sources

On FastMap and the convex hull of multivariate data: toward fast and robust dimension reduction.

FastMap is a dimension reduction technique that operates on distances between objects. Although only distances are used, implicitly the technique assumes that the objects are points in a p-dimensional Euclidean space. It selects a sequence of k < or = p orthogonal axes defined by distant pairs of points (called pivots) and computes the projection of the points onto the orthogonal axes. We show that FastMap uses only the outer envelope of a data set. Pivots are taken from the faces, usually vertices, of the convex hull of the data points in the original implicit Euclidean space. This provides a bridge to results in robust statistics, where the convex hull is used as a tool in multivariate outlier detection and in robust estimation methods. The connection sheds new light on the properties of FastMap, particularly its sensitivity to outliers, and provides an opportunity for a new class of dimension reduction algorithms, RobustMaps, that retain the speed of FastMap and exploit ideas in robust statistics.

Algorithms↗

An SVM-based algorithm for identification of photosynthesis-specific genome features.

This paper presents a novel algorithm for identification and functional characterization of "key" genome features responsible for a particular biochemical process of interest. The central idea is that individual genome features are identified as "key" features if the discrimination accuracy between two classes of genomes with respect to a given biochemical process is sufficiently affected by the inclusion or exclusion of these features. In this paper, genome features are defined by high-resolution gene functions. The discrimination procedure utilizes the Support Vector Machine classification technique. The application to the oxygenic photosynthetic process resulted in 126 highly confident candidate genome features. While many of these features are well-known components in the oxygenic photosynthetic process, others are completely unknown, even including some hypothetical proteins. It is obvious that our algorithm is capable of discovering features related to a targeted biochemical process.

Algorithms↗