Biomedical subjects
Gerhard Mostbeck
Publications and source records attributed to Gerhard Mostbeck.
Diagnosis of thoracic splenosis by ferumoxides-enhanced magnetic resonance imaging.
We report on a 56-year-old woman with a history of splenectomy and surgery of the left hemidiaphragm, who presented with multiple pleural and mediastinal mass lesions. On the basis of the patient's history of splenectomy and missing Howell-Jolly bodies in peripheral blood smears, splenosis was suspected. To confirm the presumptive diagnosis, ferumoxides-enhanced magnetic resonance was performed. As all lesions showed a pronounced signal loss on T2* sequences, the diagnosis of splenosis was made and was further confirmed by scintigraphy. The reported case illustrates that ferumoxides-enhanced magnetic resonance imaging may be a helpful tool for the evaluation of suspected splenosis.
Findings at helical CT-enteroclysis in symptomatic patients with crohn disease: correlation with endoscopic and surgical findings.
PURPOSE: The purpose of our study was to assess the diagnostic potential of helical CT-enteroclysis (HCTE) and to correlate our findings to endoscopic and surgical results. METHODS: Twenty-eight consecutive patients suffering from histologic proven Crohn disease underwent HCTE and endoscopy within 4 weeks. HCTE findings were read by two observers in consensus and compared with endoscopic and surgical results. RESULTS: Morphological signs of an acute or recurrent bowel inflammation were found in 25 of 28 (89%) patients. HCTE demonstrated accurately all mural and extramural changes of the inflamed bowel walls. Moreover, in 18 of 25 (72%) patients, HCTE depicted additional pathologic changes such as fistulas, abscesses, and skip lesions, all of which could not be visualized by endoscopy. CONCLUSION: HCTE is an accurate technique to detect mural and extramural abnormalities in patients with Crohn disease. HCTE should be considered as a complementary imaging method to endoscopy, and should be the first imaging method especially when Crohn-associated complications are suspected.