Biomedical subjects

Gh Munteanu

Publications and source records attributed to Gh Munteanu.

8 recordsLinked to original sources

PubMed2004

[Combined hamartoma of the retina and retinal pigment epithelium].

We report the case of a 31-year-old man who developed a combined hamartoma of the retina and retinal pigment epithelium in the left eye. The diagnosis was determined based on alterations discovered on fundus examination: hyperplasia of the retinal pigment epithelium cells and tortuosity of the vessels and glial epiretinal membrane. These modifications made it possible to differentiate the hamartoma from choroidal melanoma. The patient underwent photocoagulation therapy. His death due to stroke 4 years after therapy made it possible to analyze the eyeball. Histopathological examination revealed alterations due to retinal photocoagulation as well as alterations particular to the primary tumor: hypertrophy of the retinal pigment epithelium and glial and vascular overgrowth.

Adult↗

PubMed2004

[The place of photodynamic therapy in the treatment of age-related macular degeneration].

Age-related macular degeneration (ARMD) is a multifactorial disease, with unknown etiology, which represents one of the main causes of legal blindness. At this moment, the only treatment for ARMD is symptomatic and concerns the distinction of the choroidal neovascularisation (CNV). There are many therapeutical procedures, and their classification is difficult. The dynamic phototherapy (PDT) with intravenous injection of verteporfirin (Visudyne), a recent therapeutic concept based on a photochemical reaction, represents the only standard procedure for destroying the macular CNVs. The paper presents new therapeutical procedures, discussing them in relation with PDT. Beside the PDT and its supporting methods, other competing techniques (transpupillary thermotherapy, surgical removal, anti-angiogenesis and antioxidants) are presented.

Antioxidants↗

PubMed2003

[Congenital retinal macro-vessel].

This is to show the case of a 40 year old patient, where a congenital retinal macro-vessel was found, the peculiarities of which are increased calibre, intersection of the macular area, arteriovenous shunts and lack of functional disturbances. The disease is rare and its lesional and functional stability is remarkable.

Adult↗

PubMed2003

[Combined hamartoma of pigment epithelium and retina].

This is the description of the case of a 36 year old male, who developed a combined hamartoma of the pigment epithelium and retina in the left eye. The location of the lesion in the macular zone, as well as the peculiar aspect of disease, raised some issues related to differential diagnosis. Attention was paid to the diseases of the posterior pole of eyeball, which, given their aspect of disease, result of a secondary hyperplastic reaction of the EPR, can embody a type of combined pseudohamartoma: retraction syndrome, retinal angiomatosis, pseudohistoplasmosis and others. A 5 years clinical supervision of the patient didn't show major changes.

Adult↗

PubMed2003

[Conjunctival-palpebral Kaposi's angiosarcoma: report of a case].

We describe the case of a 71-year-old man who developed classic Kaposi's sarcoma with conjunctival-palpebral involvement. The diagnosis was made based on clinical and histopathological findings. The lesions of the palpebral and conjunctival teguments were of a nodular tumorous aspect, their clinical particularities similar to other tegumental involvement. The clinical elements, histopathology, and pathogenesis are debated. The effects of local therapy, consisting of intralesional injections with alpha interferon and cryotherapy, were transient.

Aged↗

PubMed2003

[Central serous chorioretinopathy and serous detachment of the pigmentary epithelium. Pathogeny relations].

A number of 7 cases of association of pigment epithelial serous detachment with central serous chorioretinopathy were described. The dye leakages were located at the periphery of the serous detachment (6 cases) and on its anterior surface (1 case). These are due to RPE breaking, as a result of the tension exerted by the build up of choroidal exudate în the subretinal space. Given the circumstances, central serous chorioretinopathy is an atypical clinical type, subsequent to the alterations of the overlying pigment epithelium. This one is differing from the classic type, because of the wide area of the serous detachment and the peripheral location of the dye leakages.

Adult↗

PubMed2003

[Diffuse retinal epitheliopathy].

This is the case of a 45 year man, with diffuse retinal epitheliopathy. The diagnosis was based on the angiofluorographic triad--diffusion sites; triangular lesions of the EPR, located vertically; serous detachments of the EPR. The therapy consisting of photocoagulation of the diffusion sites and of the harmed areas of the EPR led to a standstill of the clinical evolution, during a one year follow up period.

Fluorescein Angiography↗

PubMed2002

[Cutaneous palpebral anthrax].

The interest for anthrax is permanent because of its difficult diagnosis, its severe prognosis, and the possibility of its dissemination during biological war and bioterrorism. Cutaneous anthrax is an infectious disease caused by Bacillus anthracis. Palpebral localizations are rare, raising problems of differential diagnosis. The case of a 21-year-old male with palpebral anthrax is presented. The diagnosis was established by the progression of the palpebral lesions (serohemorrhagic vesicle, black necrotic eschar), extended palpebral edema, and positive epidemiological data. During the onset period, the differential diagnosis was difficult because of uncharacteristic symptoms, negative bacteriological tests (previous antibiotic treatment), and the absence of epidemiological data. Treatment with G penicillin led to the patient's cure.

Adult↗