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Biomedical subjects

Gianaugusto Slavich

Publications and source records attributed to Gianaugusto Slavich.

5 recordsLinked to original sources
PubMed2006

Successful treatment of polymicrobial multivalve infective endocarditis. Multivalve infective endocarditis.

A 57-year-old man presented with triple valve infective endocarditis. There were vegetations on the tricuspid, mitral, and aortic valve. He had multiple complications such as pulmonary abscess, severe anaemia, and congestive heart failure. His general condition was extremely poor. Intensive medical therapy, such as blood transfusion, mechanical ventilation, and inotropic support, allowed him to tolerate surgery. Triple valve replacement was successfully performed without major complication. Vegetation cultures grew Streptococcus bovis and Enterecoccus faecalis. At 1 year follow-up, the patient is alive in NYHA functional class I.

Anemia↗
PubMed2006

[Pseudoischemic ST-segment due to atrial repolarization during exercise test. Review of the literature, diagnostic criteria and personal experience].

Atrial repolarization wave has been known since many years: it is opposite in direction to P wave, may have a magnitude of 100 to 200 microV and may extent into the ST segment (usually it is hidden in the QRS complex). It was hypothesized that this wave could cause ST-segment depression mimicking myocardial ischemia. The false positive response is characterized by marked downsloping of the PR segment at peak exercise, longer exercise time (> 6 min), peak exercise heart rate > 125 bpm, absence of chest pain and ST-segment normalization in the first minute of recovery. In our experience a role of atrial repolarization in ST-segment depression was found in 5.5% of 144 consecutive and non-selected individuals evaluated with exercise testing.

Electrocardiography↗
PubMed2002

[Atrial fibrillation: always cardioversion? Yes].

It is obvious that sinus rhythm is preferable to atrial fibrillation for the improvement of the clinical conditions of patients and to avoid the risks of anticoagulation. This clinical reality associated with recent scientific evidence, i.e. atrial fibrillation can be treated with focal ablation, a fibrillating atrium undergoes an unfavorable remodeling that can negatively influence attempts of electrical cardioversion, results of clinical studies have demonstrated that a large atrial size and long-standing atrial fibrillation do not represent a contraindication to electrical cardioversion, explain why at present cardiologists try to maintain normal sinus rhythm more than in the past. Results of current studies that compare rate control versus sinus rhythm maintenance could solve the controversy.

Atrial Fibrillation↗
PubMed2002

Significance of ST-segment depression during supraventricular tachycardia. Clues offered by its return to normal at the end of the episode.

The finding of transient ST-segment depression during episodes of supraventricular tachycardia is common but its ischemic significance is usually uncertain. Several authors came to the conclusion that in the absence of positive myocardial scintigraphy these alterations are not associated with a coronary flow-limiting stenosis. Our report tends to confirm this view but we suggest to observe the evolution of ST-segment changes at the very end of the episodes; these mechanisms have not been adequately addressed in previous studies and could provide useful clues to the ischemic or non-ischemic origin of ST-segment abnormalities.

Electrocardiography↗