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Biomedical subjects

Gilberto Mastrocola Manzano

Publications and source records attributed to Gilberto Mastrocola Manzano.

7 recordsLinked to original sources

Perceptions and electric senoidal current stimulation.

OBJECTIVE: To analyze the relationship between perceptions and electrical senoidal current stimulation (ESCS). METHOD: The study population comprise 100 healthy volunteers. ESCS of 5 Hz and 2 kHz were applied to the left index finger at one and 1.5 sensory threshold. Following each stimulus train a list of eight words (four related to thin fiber sensations and four related to thick fiber sensations) was presented to the subjects who were asked to choose the three words closer to the experienced sensation. Each chosen word was given a score 1; final results were obtained by the sum of the scores for the words related to thin and thick fiber systems for each situation. RESULTS: For 5 Hz ESCS at one and 1.5 sensory threshold thin fibers had significantly higher scores than thick fibers; for 2 kHz ESCS, thick fibers had significantly higher scores. CONCLUSION: These results show that there is a relation between different sensations and ESCS of different frequencies.

Adolescent↗

[Determination of electric current perception threshold in a sample of normal volunteers].

Reference values using the instrument Neurometer were determined and compared with those suggested by the manufacturer; the sensory thresholds for the different frequencies in different body segments were determined; the influence of age, level of education, gender and the reutilization of the electrodes in the different sites were also evaluated. Sensory threshold was determined in 101 normal volunteers (68 women), ages ranged from 17 to 87 years old. The procedure was fully automated with the sensory threshold being determined by the method of limits followed by the forced choice method. Analysis of the results revealed that: there was a significant difference between the values obtained for the index fingers and the halux; no difference was detected between both index fingers; gender and level of instruction had no effect on the results, age had a small influence after stimulation with 2000Hz and 250Hz; three reutilizations of the electrodes did not affect the results on the index fingers, however at the halux, the third utilization deteriorated the results from the 2000Hz stimulation. Except for the 2000Hz stimulation, significant differences were suggested between the values reported here and those provided by the manufacturer.

Adolescent↗

[Pudendo-anal reflex in normal women].

The pudendo-anal reflex was studied in a sample of 31 normal women. Responses were obtained after bilateral independent stimulation of the clitoris, with surface recordings from both sides of the external anal sphincter. Responses were elicited with double-pulses of 0.2 ms duration with a interstimulus interval of 5 ms, frequency of stimulation was lower than 0.5 Hz. A minimal of four responses were recorded after supramaximal stimulation. In one volunteer no response was recorded after unilateral stimulation. Latencies of the responses from the right and left sides of the anal sfincter after right and left stimulation were 36.35+/-6.37, 36.28+/-6.23, 35.88+/-4.68, 36.44+/-4.45 ms, respectively. No relation was detected between latencies and age, body mass index and parity (considering either total parity or vaginal delivery only). In 12% of the recordings uncertainty was introduced in the latency measurements related to a poor signal-noise ratio.

Adolescent↗

Various aspects of F-wave values in a healthy population.

OBJECTIVE: To characterize various aspects of F-wave in a healthy population and establish normative data for future clinical use. METHODS: A total of 100 healthy volunteers underwent sensory and motor nerve conduction studies of the ulnar and tibial nerves, including F waves elicited by 32 stimuli. RESULTS: The F-wave measurements (mean +/- SD for ulnar vs tibial nerve) consisted of persistence (83 +/- 19 vs 97 +/- 5%), minimum, mean and maximum latencies (26.5 +/- 2.1, 28.1 +/- 2.2, and 30.4 +/- 2.3 vs 47.0 +/- 4.1, 49.6 +/- 4.4, and 52.5 +/- 4.4 ms), minimum, mean and maximum F-wave conduction velocities (FWCV) (55.0 +/- 2.7, 60.0 +/- 2.3, and 64.0 +/- 3.0 vs 49.0 +/- 2.9, 52.2 +/- 3.1, and 55.5 +/- 3.4 m/s), chronodispersion (3.9 +/- 0.9 vs 5.5 +/- 1.4 ms), mean amplitude (347 +/- 152 vs 384 +/- 148 microV) and mean duration (8.6 +/- 2.9 vs 13.0 +/- 4.5 ms). Additional measures, registered by electronic averaging, included latency (27.4 +/- 2.3 vs 48.6 +/- 4.7 ms), duration (9.6 +/- 2.2 vs 16.4 +/- 4.2 ms), and amplitude (299 +/- 156 vs 208 +/- 116 microV). CONCLUSIONS: The use of a height nomogram serves well as an acceptable means to adjust F latencies for the limb length. In addition to the commonly used minimal latency, maximal FWCV, and persistence, clinically relevant measures with a narrow variability includes mean and maximal latencies, chronodispersion, and mean duration. In particular, mean latency obtained with 10 stimuli gave accurate results either for group or individual analysis. SIGNIFICANCE: The data help establish an adequate manner of recording F-wave latencies in clinical evaluation.

Adolescent↗

[Translation and validation of an instrument for evaluation of severity of symptoms and the functional status in carpal tunnel syndrome].

The objective of the present study was to translate, to do cultural equivalence and validation of the Levine et al. (1993) or Boston Carpal Tunnel Questionnaire (BCTQ) to Portuguese. The BCTQ application to patients, selected by the question "What was the reason that brought you to look for a physician and that led him to ask this examination?" showed very good reproducibility. The validity was measured through the comparison of the severity symptoms scores (SSS) and the functional status scores (FSS) with the results of grip forces, Minnesota, two point discrimination, Semmes-Weinstein filaments perception and sensory conduction at the median nerve. The internal consistency was evaluated through Chronbach's alpha coefficient comparing the SSS and the FSS. The measuring properties were evaluated through paired t-test between pre and pos-surgical scores. Reproducibility, internal consistency, validation and measuring properties of the translated BCTQ were similar to those found by Levine et al. with the original version.

Carpal Tunnel Syndrome↗

[Paresthesia and/or pain affecting the hand and/or wrist as a referral for electrodiagnostic studies].

To study the reasons for referral to electrodiagnostic evaluation, 490 patients referred for electrodiagnostic evaluation to two laboratories (UNIFESP and UNEF) answered the following question: "What was the reason that brought you to look for a physician and that led him to ask this examination?" Paresthesia and/or pain were answered as the main reason by 175 of them (26% UNIFESP and 40% UNEF). The electromyographical examinations were normal in 30.8% and 35.3% and involvement of the median nerve at the wrist was detected in 5 9% and 51.5% of them. Nocturnal symptoms and paresthesia were commonly noted in both groups of patients; they, however, were not able to separate the patients with and without median nerve compression at the wrist. The question asked seems to be a useful selection instrument, to select two similar symptomatic samples of patients from two laboratories serving with very different target populations.

Brazil↗