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Biomedical subjects

Giovanni Volpe

Publications and source records attributed to Giovanni Volpe.

3 recordsLinked to original sources

Torque detection using Brownian fluctuations.

We report the statistical analysis of the movement of a submicron particle confined in a harmonic potential in the presence of a torque. The absolute value of the torque can be found from the auto- and cross-correlation functions of the particle's coordinates. We experimentally prove this analysis by detecting the torque produced onto an optically trapped particle by an optical beam with orbital angular momentum.

Journal Article↗

Surface plasmon radiation forces.

We report the first experimental observation of momentum transfer from a surface plasmon to a single dielectric sphere. Using a photonic force microscope, we measure the plasmon radiation forces on different polystyrene beads as a function of their distance from the metal surface. We show that the force magnitude at resonance is strongly enhanced compared to a nonresonant illumination. Measurements performed as a function of the probe particle size indicate that optical manipulation by plasmon fields has a strong potential for optical sorting.

Energy Transfer↗

Real-time detection of hyperosmotic stress response in optically trapped single yeast cells using Raman microspectroscopy.

Living cells survive environmentally stressful conditions by initiating a stress response. We monitored changes in the Raman spectra of optically trapped Saccharomyces cerevisiae yeast cell under normal, heat-treated, and hyperosmotic stress conditions. It is shown that when glucose was used to exert hyperosmotic stress, two chemical substances-glycerol and ethanol-can be monitored in real time in a single cell.

Ethanol↗