Efficacy of 2% lignocaine gel in pterygium surgery.
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Anesthesia, Local↗
Biomedical subjects
Gloria Y S Leung
Publications and source records attributed to Gloria Y S Leung.
Late traumatic flap dislocations after LASIK.
PURPOSE: To report the management and outcome of late onset traumatic dislocation of LASIK flaps. METHODS: This retrospective, interventional case series presents three patients with late onset LASIK flap dislocation following mechanical trauma 1 to 7 years postoperatively. RESULTS: In all cases, the flap was surgically repositioned. Epithelial ingrowth was removed and diffuse lamellar keratitis was treated with an intensive steroid regimen. All patients returned to their preoperative best spectacle-corrected visual acuity. Aggressive steroid treatment during the perioperative period and meticulous handling of the epithelium are important in preventing further recurrence. CONCLUSIONS: Laser in situ keratomileusis flaps may experience mechanical dislocation as late as 7 years postoperatively. Diffuse lamellar keratitis and epithelial ingrowth are associated with flap dislodgment.
Administration, Topical↗
Preliminary in vitro evaluation of 2-octyl cyanoacrylate (Dermabond) to seal corneal incisions.
OBJECTIVE: To compare the efficacy of Dermabond with conventional nylon sutures for sealing linear corneal incisions. METHODS: A keratome knife was used to create a 4-mm full-thickness linear corneal incision anterior to the limbal arcade in 20 fresh pig eyes. The incision was sealed with Dermabond tissue adhesive or closed with 10-0 nylon sutures. A 27-gauge needle connected via tubing to a bottle containing balanced salt solution (BSS) was inserted into the anterior chamber. Infusion pressure was controlled by varying the height of the column of BSS. The tensile strength of the incisions was measured by increasing the infusion pressure to the point where leakage was noted. RESULTS: The mean height at which leakage was detected was 100.20 +/- 31.19 cm H(2)O (equivalent to a pressure of 73.70 +/- 22.99 mm Hg) for the nylon suture group (n = 10 eyes) and 113.80 +/- 31.20 cm H(2)O (equivalent to a pressure of 83.71 +/- 22.95 mm Hg) for the Dermabond group (n = 10 eyes). The difference was not significant (P = 0.343). CONCLUSIONS: The mean leakage pressures were comparable for the 2 groups. Either method of closure should be able to withstand any postoperative increases in intraocular pressure. Dermabond adhesive may be considered as an alternative to conventional sutures in corneal wound closure.
Animals↗
Successful treatment of surgically induced necrotizing scleritis with tacrolimus.
A 46-year-old man developed surgically induced necrotizing scleritis (SINS) 7 months following uneventful primary bare sclera pterygium excision. The patient underwent two scleral patch grafts for SINS but despite the use of cyclophosphamide and azathioprine, the scleral patch grafts failed within 1 month of surgery on both occasions. Tacrolimus was used for his third scleral patch graft. No recurrence of necrotizing scleritis was observed for 2 years. Tacrolimus may be considered as a valuable adjunctive immunosuppressant in the management of resistant necrotizing scleritis.
Graft Survival↗