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Gocha Khelashvili

Publications and source records attributed to Gocha Khelashvili.

2 recordsLinked to original sources

A physical model of multiple-image radiography.

We recently proposed a phase-sensitive x-ray imaging method called multiple-image radiography (MIR), which is an improvement on the diffraction-enhanced imaging technique. MIR simultaneously produces three images, depicting separately the effects of absorption, refraction and ultra-small-angle scattering of x-rays, and all three MIR images are virtually immune to degradation caused by scattering at higher angles. Although good results have been obtained using MIR, no quantitative model of the imaging process has yet been developed. In this paper, we present a theoretical prediction of the MIR image values in terms of fundamental physical properties of the object being imaged. We use radiative transport theory to model the beam propagation, and we model the object as a stratified medium containing discrete scattering particles. An important finding of our analysis is that the image values in all three MIR images are line integrals of various object parameters, which is an essential property for computed tomography to be achieved with conventional reconstruction methods. Our analysis also shows that MIR truly separates the effects of absorption, refraction and ultra-small-angle scattering for the case considered. We validate our analytical model using real and simulated imaging data.

Algorithms↗

New methods for EXAFS analysis in structural genomics.

Data analysis is one of the remaining bottlenecks in high-throughput EXAFS for structural genomics. Here some recent developments in methodology are described that offer the potential for rapid and automated XAS analysis of metalloproteins.

Genes↗