Biomedical subjects

Gottfried Reznicek

Publications and source records attributed to Gottfried Reznicek.

4 recordsLinked to original sources

PubMed2006

Infrared spectroscopy as a tool for chemotaxonomic investigations within the Achillea millefolium group.

An FT-IR-based method for the rapid characterization and identification of Achillea species was developed. With the IR spectra of the CH2Cl2 extracts of A. aspleniifolia, A. collina, A. millefolium, A. millefolium ssp. sudetica, A. pannonica, A. pratensis, A. roseoalba, A. setacea, and A. styriaca, a spectrum library was created. This database allowed the identification of the respective taxa by comparison of IR spectra. Moreover, information concerning dominant structural elements of sesquiterpene constituents was obtained, providing hints about the composition of a plant sample of unknown origin.

Achillea↗

PubMed2005

Phenolic and terpenoid compounds from Chione venosa (sw.) urban var. venosa (Bois Bandé).

The Caribbean island of Grenada furnishes the popular aphrodisiac drug Bois Bandé, which consists of the stem bark and the roots of Chione venosa (sw.) URBAN var. venosa (Rubiaceae), a native tree growing in the islands' rain forest. The phytochemical investigation of dichloromethane and methanolic-aqueous extracts of the bark and the roots yielded three acetophenone derivatives described for the first time in plants - ortho-hydroxy-acetophenone-azine (1), acetophenone-2-O-[beta-D-apiofuranosyl-(1''-->6')-O-beta-D-glucopyranoside] (2) and acetophenone-2-O-beta-D-glucopyranoside (3) - along with five known compounds, alpha-morroniside (4), sweroside (5), diderroside (6), daucosterol (7) and beta-sitosterol (8). Their structures were elucidated by 1D and 2D NMR analysis, UV-Vis and ESI-MS.

Acetophenones↗

PubMed2004

Morphological, chemical and functional analysis of catuaba preparations.

Fourteen commercial samples of the popular Brazilian aphrodisiac Catuaba specified as bark drugs of Anemopaegma, Erythroxylum and Trichilia species were examined for identity and purity. Only a minority of the examined Catuaba samples contained the crude drugs claimed on the labels. More than half of the products were adulterated with different crude drugs. The majority of the samples contained a bark originating from Trichilia catigua. The TLC fingerprints confirmed the heterogeneity, in 50% of the samples tropane alkaloids of various concentrations were detected. TLC and HPLC methods for separation and identification of the tropane alkaloids were developed and their analytical data (RF values, retention times, ESI-MS) given. The structure elucidation of the two main alkaloids, catuabine D and its hydroxymethyl derivative, is presented. The 1H- and 13C-NMR assignments of these alkaloids are discussed with regard to literature data. Neither aqueous nor methanolic extracts of the Trichilia catigua reference material nor alkaloid-enriched fractions of commercial samples showed any effect on the rabbit corpus cavernosum in an in vitro test.

Animals↗

PubMed2004

Anthrone C-glucosides from Rheum emodi.

In a study of the anthraderivatives in roots of Rheum emodi, three new anthrone C-glucosides, named 10-hydroxycascaroside C (1), 10-hydroxycascaroside D (2) and 10R-chrysaloin 1-O-beta-D-glucopyranoside (3) were isolated besides the rare compounds cascaroside C (4), cascaroside D (5) and cassialoin (6). Additionally the investigation resulted in the isolation of an acetylated chrysophanol glucoside, 8-O-beta-D-(6'-O-acetyl)glucopyranosyl-chrysophanol (7). The structures were established by comprehensive spectroscopic investigations.

Acetylation↗