Biomedical subjects

Gowri Ramanathan

Publications and source records attributed to Gowri Ramanathan.

2 recordsLinked to original sources

PubMed2006

IVF/ICSI in a woman with active acromegaly: successful outcome following treatment with pegvisomant.

A 29 year old woman with difficult to control acromegaly and a pituitary macroadenoma responded to pegvisomant therapy and subsequently conceived with her first cycle of in-vitro fertilization and intra-cytoplasmic sperm injection. Pregnancy was complicated by gestational diabetes, pituitary gland enlargement and deteriorating visual fields. Conservative management with elective cesarean section was performed at 32 weeks gestation. A healthy boy was delivered who remains developmentally normal at 1 year. This complex case required intricate care by a multi-disciplinary team and is likely to represent the first in many cases of assisted conception on pegvisomant therapy for active acromegaly.

Acromegaly↗

PubMed2006

Postpartum hemorrhage.

Postpartum hemorrhage (PPH) is the most important single cause of maternal death in both developing and developed countries. It arises from abnormalities in one of four basic processes, with uterine atony being the most common. A multidisciplinary approach to management is important. The value of oxytocin and prostaglandins, including misoprostol, in treatment is discussed. Recently developed, less invasive treatment options, namely uterine tamponade and compression sutures, are fast becoming valuable alternatives to the traditional options of pelvic devascularization and hysterectomy. With a stark contrast in maternal mortality from PPH between the developing and developed countries, public health strategies and medical interventions intended to minimize this are further discussed.

Embolization, Therapeutic↗