Biomedical subjects

Grazyna Malukiewicz-Wiśniewska

Publications and source records attributed to Grazyna Malukiewicz-Wiśniewska.

7 recordsLinked to original sources

PubMed2005

[Von Willebrand factor in plasma of patients with age related macular degeneration].

PURPOSE: To evaluate the plasma level of von Willebrand factor (vWf: Ag) in patients with age related macular degeneration and to establish the relation between this factor and the stage and progression of the disease. MATERIAL AND METHODS: The group studied comprised 34 patients with age related macular degeneration. Excluded were patients with diseases and with other factors which could have changed evaluated parameters. Patients studied were categorized into 7 groups according to the stage of disease. The progression of the disease was evaluated on the base of examination performed after 6 months' interval. Mean age of the patients in analysed group was 73.3 (SD = 19.5) years. The control group consisted of 32 healthy persons of similar age. Statistical analysis were performed with U Mann-Whitney test and Spearman correlation test. In both groups blood was sampled from cubital vein. In blood of patients, von Willebrand levels were measured by means of ELISA using commercial antibodies (DAKO, Denmark). RESULTS: Von Willebrand concentration was significantly higher in patients with age related macular degeneration as compared with control group (p < 0.001). Concentration of vWf: Ag correlated positively with the grade of macular changes and the progression of the disease. CONCLUSIONS: The data obtained show that age related macular degeneration is associated with elevated plasma levels of von Willebrand factor (a marker of endothelial injury) and that there is a positive correlation of it's concentration with both stage and progression of the disease.

Aged↗

PubMed2005

[Open globe injuries--selected epidemiologic features in own material].

PURPOSE: To evaluate chosen epidemiological factors in perforating eye injuries in own material MATERIAL AND METHOD: Retrospective case review over period from 2001 to 2003 hospitalised in the Department of Ophthalmology in Bydgoszcz. The group studied comprised 78 patients (79 eyes) aged from 4 to 77 years. Analyzed were following data: age, gender, the extend of the injury, visual acuity at presentation, the presence of - and intraocular foreign body nature, type of injury, professional activity, and other factors (alcohol use, glasses). RESULTS: The group studied involved 89.7% men. Mean age of all the patients was 35.6 years (SD=17.1), male: 35 years (D=17.0), female: 41 (SD=18.5). Severe wounds, including corneal and scleral laceration totaled 32.9%. In 41.8% cases initial visual acuity was less than 0.001, including 42.4% of light perception. There was no light perception in 18.2% in this group. Intraocular foreign bodies were found in 39.2% of studied eyes (75.8% involved ferromagnet metal). Domestic activities accounted for 50% of injuries, and 33.3% occurred at worksite. In the group studied there were 28.2% of unemployed, the pensioners were affected in 9%. CONCLUSIONS: Most of the penetrating eye injuries affected young males aged mean 35 and happened at home. Almost one half of the patients experienced severe injuries leading to severe visual loss. Ferromagnet metal predominated intraocular foreign bodies.

Adolescent↗

PubMed2004

[Rhegmatogenous retinal detachment in children and youth--chosen epidemiological features].

PURPOSE: To assess chosen epidemiological features (risk factors) of rhegmatogenous retinal detachment in young patients. MATERIAL AND METHODS: Retrospective evaluation of patients aged up to 18 years with rhegmatogenous retinal: detachment hospitalized in the Department of Ophthalmology, University of Medical Sciences of Bydgoszcz--in the period between 1993-2003. Studied group comprised 37 patients aged from 2 to 18 years. Excluded were the patients with retinopathy of prematurity. RESULTS: Mean age in the group studied was 12.6 (SD=3.6) years, over 80% were male. In 88.9% at least one risk factor was found--the most common of which was history of trauma (52.7%). Myopia was diagnosed in 27.7% of cases, in 8.3% patients cataract surgery had been performed prior to retinal detachment. In 8.3% of patients in group studied revealed congenital structural abnormalities. One patient (2.8%) had toxocariasis. Bilateral retinal detachment occurred also in one patient. The macula was detached in 75% and total retinal detachment was present in 38.8% of cases. CONCLUSIONS: The most common risk factor in the group studied was history of nonsurgical trauma. Prevalence of macular detachment was noted.

Adolescent↗

PubMed2002

[Astigmatism after cataract surgery].

PURPOSE: To evaluate postoperative astigmatism after cataract surgery. MATERIAL AND METHODS: The studied group consist of 135 patients subjected to cataract surgery; 75 patients (75 eyes) had extracapsular cataract extraction with 12 mm corneoscleral incision (group I); 30 patients (30 eyes) had phacoemulsification with 3.5 mm corneal incision (group II); 30 patients (30 eyes) had phacoemulsification with 3.5 mm tunnel incision (group III). Astigmatism was measured on the 6th day and 2 years after surgery. RESULTS: Mean astigmatism on the 6th postoperative day was 4, 19 D (SD = 1.20) for group I, 2.50 D (SD = 0.47) for group II and 1.79 D (SD = 0.61) for group III. The differences between all the groups were statistically significant. The astigmatism assessed 2 years after surgery returned to preoperative values and there was statistic difference only between group I and III. CONCLUSION: Two years after cataract surgery astigmatism is comparable with the preoperative values irrespective of the operation technique.

Adult↗

PubMed2002

[Senile and presenile cataract: comparison of patients operated in the year 1990-2000].

PURPOSE: To compare some epidemiological features (e.g. mean age) of patients operated for senile and presenile cataract in the year 1990 and 2000. MATERIAL AND METHOD: Data of 106 consecutive patients with senile or presenile cataract operated in May 1990 and 110 patients operated in April and May 2000, were compared. Some cataract risk factors were analysed: cataract in family, diabetes, steroid therapy, refractive error, rural residency, outdoor occupation, smoking., visual acuity and age of patients. RESULTS: There was significantly higher age (69 vs. 60 years) and lower number of patients with very low visual acuity (less than 0.1) in group undergoing cataract surgery in 2000. We did not noted significant differences regarding sex, cataract in family, presence of diabetes, steroid therapy, myopia, rural residency, outdoor occupation, smoking. CONCLUSIONS: In 10 years period increase of age and decrease in number of patients with very low visual acuity in group operated for senile and presenile cataract could be observed.

Age Factors↗

PubMed2002

[Late results of endothelial cell loss after cataract surgery].

PURPOSE: To evaluate endothelial cell loss rate after cataract surgery in 5 years-long period. MATERIAL AND METHOD: The studied group comprised 115 patients (66 females and 49 males) who had undergone senile and presenile cataract surgery. Mean age was 60 years (SD = 90). In 60 patients extracapsular cataract extraction and in 55 phacoemulsification have been performed. Mean central corneal thickness was measured before and 2 days after cataract surgery. Mean central endothelial cell density was assessed preoperatively, as well as 1, 3, 6 months and 2, 5 years after operation. RESULTS: Mean endothelial cell loss was: 76% 1 month after surgery, and 97% 3 months, 110% 6 months, 124% 2 years, 140% 5 years postoperatively. CONCLUSIONS: Enhanced endothelial cell loss could be observed even 2 years after surgery. 5 years postoperatively physiological loss rate is attained. Initial postoperative increase in central corneal thickness is an important marker of subsequent endothelial cell loss.

Cornea↗

PubMedDate not supplied

Axial length measurements after cataract surgery in adults.

UNLABELLED: The purpose of the study was to check the difference in eye axial length before and after cataract surgery and to find out the possible correlation with refraction changes. The axial length was measured by ultrasound before and after cataract extraction with intraocular lens implantation. Keratometry measurements were also performed. The study comprised 32 eyes. The mean difference in axial length was 0.53 mm. The mean difference in keratometry was 0.37 D. There was no correlation between these values. CONCLUSION: The changes in axial length are not due to corneal curve changes. Perhaps in pseudophakic eyes different ultrasound velocity should be used.

Aged↗