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Biomedical subjects

Gregory F Marchetti

Publications and source records attributed to Gregory F Marchetti.

11 recordsLinked to original sources

The reliability and validity of the Four Square Step Test for people with balance deficits secondary to a vestibular disorder.

OBJECTIVE: To determine the reliability and validity of the Four Square Step Test (FSST) for use in people with balance deficits secondary to vestibular disorders, who frequently report falling and have difficulty with changes of direction. DESIGN: Cross-sectional descriptive study. SETTING: Outpatient clinic. PARTICIPANTS: Thirty-two people with balance deficits secondary to vestibular disorders (mean age, 63.7+/-17.8y) who were currently enrolled in a vestibular physical therapy program agreed to participate. INTERVENTIONS: Participants performed the FSST, the Timed Up & Go (TUG) test, an 11-m walk test during which walking speed was recorded, and the Dynamic Gait Index (DGI) and completed the Dizziness Handicap Inventory (DHI) and the Activities-Specific Balance Confidence (ABC) Scale. MAIN OUTCOME MEASURES: The main outcome measures were the FSST time, TUG results, DGI score, gait velocity, and DHI and ABC scores. Number of fall risk factors, as determined by published scores for people at risk for falling on the TUG test and gait speed, and number of falls were compared with FSST scores. RESULTS: The FSST has good reliability (intraclass correlation coefficient, model 3,1: .93; 95% confidence interval, .86-.96) and had good correlations with the other gait measures (correlation coefficients for the TUG, .69; gait speed, .65; DGI, -.51) and poor correlations with the DHI and the ABC (DHI, -.13; ABC, -.12). Multivariate linear regression showed that 51.5% of FSST performance was explained by TUG score and gait speed. The mean FSST time differed significantly between groups with 0 (n=12), 1 (n=12), or 2 to 3 (n=8) risk factors for falls (analysis of variance, F=10.02; P<.01). A cutoff score of greater than 12 seconds on the FSST was associated with a sensitivity of 80% and specificity of 92% for the identification of subjects with 1 or more risk factors for falls. CONCLUSIONS: The FSST is a reliable and valid tool for measuring the ability to perform multidirectional movements in people with balance deficits secondary to vestibular disorders.

Accidental Falls↗

Construction and validation of the 4-item dynamic gait index.

BACKGROUND AND PURPOSE: People with balance disorders often have difficulty walking. The purpose of this study was to develop and test the psychometric properties of a short form of the Dynamic Gait Index (DGI) for the clinical measurement of walking function in people with balance and vestibular disorders. SUBJECTS: A total of 123 subjects with such disorders (test subjects) and 103 control subjects were included in this study. METHODS: Rasch and factor analyses were used to create a short form of the DGI. Internal consistency and discriminative validity for test subjects versus control subjects and for falling versus nonfalling test subjects were evaluated. RESULTS: Four items were selected for the shorter version of the test: gait on level surfaces, changes in gait speed, and horizontal and vertical head turns. DISCUSSION AND CONCLUSION: The clinical psychometric properties of the 4-item DGI were equivalent or superior to those of the 8-item test. The 4-item DGI can be used by clinicians to measure gait in people with balance and vestibular disorders without compromising important clinical measurement characteristics.

Adolescent↗

Physical therapy for central vestibular dysfunction.

OBJECTIVE: To determine if vestibular physical therapy (PT) leads to improved functional outcomes in people with central vestibular dysfunction. DESIGN: Retrospective case series. SETTING: Outpatient PT clinic. PARTICIPANTS: Forty-eight patients with central vestibular dysfunction met the criteria for inclusion in this retrospective chart review. The 48 patients were divided into various subgroups including central vestibulopathy, cerebellar dysfunction, stroke, mixed central and peripheral vestibulopathy, and posttraumatic central disorders. INTERVENTION: Patients were treated with a custom-designed PT program for a mean of 5 visits over an average of 5 months. MAIN OUTCOME MEASURES: Patients completed the Activities-Specific Balance Confidence Scale, the Dizziness Handicap Inventory (DHI), the Dynamic Gait Index, the Timed Up & Go test, and the Five Times Sit-to-Stand (FTSTS) Test. RESULTS: Significant differences were demonstrated between initial evaluation and discharge in each of the assessment measures for the entire group. Post hoc tests were performed to determine if there was a significant difference in any of the assessment measures by diagnosis. Central vestibular diagnostic subgroup was shown to affect pre- to postintervention differences in the functional and disability measures (P< or =.05). With the exception of the FTSTS, effect sizes of change due to PT intervention were greater in those persons with severe disability at baseline as determined by a DHI score of more than 60. CONCLUSIONS: Patients with central vestibular dysfunctions improved in both subjective and objective measures of balance after PT intervention. Persons with cerebellar dysfunction improved the least.

Aged↗

The relationship between falls history and computerized dynamic posturography in persons with balance and vestibular disorders.

OBJECTIVE: To describe the relationship between Sensory Organization Test (SOT) scores and reported falls in persons with vestibular and balance disorders. DESIGN: Descriptive cross-sectional. SETTING: Outpatient tertiary balance and falls clinic. PARTICIPANTS: One hundred physical therapy (PT) charts of people referred to a balance and falls clinic were reviewed. Criteria for inclusion were that the patients had completed the SOT of computerized dynamic posturography (CDP), had a vestibular diagnosis, and had the numbers of falls recorded from patient report within the last 6 months at the initial examination. Rotational chair, caloric testing, oculomotor test, and Activities-Specific Balance Confidence (ABC) results were recorded, if available. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: The SOT composite and ABC scores as they related to reports of falls in the last 6 months. RESULTS: The overall proportion of persons with vestibular disorders with positive 6-month history for 1 or more falls was 30% and for recurrent falls (>/=2) was 17%. Vestibular laboratory findings, age, sex, and vestibular diagnosis were not related to reported falls status. Patients who reported multiple falls prior to the PT examination had lower SOT composite scores than patients who reported 1 or no falls in the previous 6 months. The receiver operating characteristic curve identified a composite SOT score of less than 38 as demonstrating the highest likelihood ratio for differentiating between those people who reported no falls in the past 6 months and those who reported 2 or more falls. CONCLUSIONS: Persons who are recurrent fallers perform worse on SOT than either nonfallers or 1-time fallers. CDP performance can help guide the clinician in the development of a safe exercise program.

Accidental Falls↗

Predicting caregiver assistance required for sit-to-stand following rehabilitation for acute stroke.

OBJECTIVE/METHODS: The objective of this case series was to determine the relationship between impairments identified at hospital admission and a reduced need for sit-to-stand (STS) assistance during an inpatient rehabilitation hospital stay. Fifty- five inpatients with a diagnosis of acute stroke were retrospectively studied. Demographic information and the following admission and discharge measures were collected from a chart review: bilateral dorsiflexion PROM, strength of the unaffected leg, Motricity Index (MI), presence of hemi-neglect, gait velocity, and Functional Independence Measure (FIM) scores for STS, ambulation, and cognition. Sit to stand improvement was determined by a change of at least one Caregiver Assistance Level (CAL) in STS performance between hospital admission and discharge. CAL 1 = STS FIM score of 7 or 6; CAL 2 = STS FIM score of 5; CAL 3 = STS FIM score of 4, 3, 2, or 1. RESULTS: Unaffected knee extension strength, Motricity Index (MI) score, FIM cognition scores, and bilateral ankle dorsiflexion PROM were each univariate, age-adjusted predictors of improvement in STS CAL. A multivariate, 3 main-effect model that included admission FIM cognitive scores and ankle PROM correctly predicted 90.6% (48 out of 53) of the possible sit to stand improvement outcomes. Admission gait velocity and MI differentiated extent of functional change in those who improved. CONCLUSIONS: Cognition and bilateral ankle dorsiflexion PROM most strongly predicted STS CAL improvement during an inpatient rehabilitation stay. Caregivers of patients with significant impairments may benefit from early and intensive training on how to assist their family member in the STS task.

Activities of Daily Living↗

Usefulness of the dizziness handicap inventory in the screening for benign paroxysmal positional vertigo.

OBJECTIVE: The purpose of the study was to determine whether a newly developed subscale of the Dizziness Handicap Inventory (DHI) could assist in the screening of benign paroxysmal positional vertigo (BPPV). STUDY DESIGN: Retrospective case review. SETTING: Tertiary balance referral center. PATIENTS: Charts of 383 patients (mean age, 61 yr) with a variety of vestibular diagnoses (peripheral and central) were reviewed. INTERVENTIONS: Patients completed the DHI before the onset of physical therapy intervention. MAIN OUTCOME MEASURES: A newly developed BPPV subscale developed from current DHI items was computed to determine whether the score could assist the practitioner in identifying individuals with BPPV. RESULTS: Individuals with BPPV had significantly higher mean scores on the newly developed BPPV subscale of the DHI (p < 0.01). The five-item BPPV score was a significant predictor of the likelihood of having BPPV (chi2 = 8.35; p < 0.01). On the two-item BPPV scale, individuals who had a score of 8 of 8 were 4.3 times more likely to have BPPV compared with individuals who had a score of 0. CONCLUSION: Items on the DHI appear to be helpful in determining the likelihood of an individual having the diagnosis of BPPV.

Adolescent↗

Clinical measurement of sit-to-stand performance in people with balance disorders: validity of data for the Five-Times-Sit-to-Stand Test.

BACKGROUND AND PURPOSE: People with balance disorders are characterized as having difficulty with transitional movements, such as the sit-to-stand movement. A valid and feasible tool is needed to help clinicians quantify the ability of people with balance disorders to perform transitional movements. The purpose of this study was to describe the concurrent and discriminative validity of data obtained with the Five-Times-Sit-to-Stand Test (FTSST). The FTSST was compared with the Activities-specific Balance Confidence Scale (ABC) and the Dynamic Gait Index (DGI). SUBJECTS AND METHODS: Eighty-one subjects without balance disorders and 93 subjects with balance disorders were recruited for the study. Each subject was asked to stand from a 43-cm-high chair 5 times as quickly as possible. The ABC and DGI scores were recorded. RESULTS: Subjects with balance disorders performed the FTSST more slowly than subjects without balance disorders. Discriminant analysis demonstrated that the FTSST correctly identified 65% of subjects with balance dysfunction, the ABC identified 80%, and the DGI identified 78%. The ability of the FTSST to identify subjects with balance dysfunction was better for subjects younger than 60 years of age (81%). DISCUSSION AND CONCLUSION: The FTSST displays discriminative and concurrent validity properties that make this test potentially useful in clinical decision making, although overall the ABC and the DGI are better than the FTSST at discriminating between subjects with and subjects without balance disorders.

Adolescent↗

Reliability, internal consistency, and validity of data obtained with the functional gait assessment.

BACKGROUND AND PURPOSE: The Functional Gait Assessment (FGA) is a 10-item gait assessment based on the Dynamic Gait Index. The purpose of this study was to evaluate the reliability, internal consistency, and validity of data obtained with the FGA when used with people with vestibular disorders. SUBJECTS: Seven physical therapists from various practice settings, 3 physical therapist students, and 6 patients with vestibular disorders volunteered to participate. METHODS: All raters were given 10 minutes to review the instructions, the test items, and the grading criteria for the FGA. The 10 raters concurrently rated the performance of the 6 patients on the FGA. Patients completed the FGA twice, with an hour's rest between sessions. Reliability of total FGA scores was assessed using intraclass correlation coefficients (2,1). Internal consistency of the FGA was assessed using the Cronbach alpha and confirmatory factor analysis. Concurrent validity was assessed using the correlation of the FGA scores with balance and gait measurements. RESULTS: Intraclass correlation coefficients of.86 and.74 were found for interrater and intrarater reliability of the total FGA scores. Internal consistency of the FGA scores was.79. Spearman rank order correlation coefficients of the FGA scores with balance measurements ranged from.11 to.67. DISCUSSION AND CONCLUSION: The FGA demonstrates what we believe is acceptable reliability, internal consistency, and concurrent validity with other balance measures used for patients with vestibular disorders.

Adult↗

The sensitivity and specificity of the Timed "Up & Go" and the Dynamic Gait Index for self-reported falls in persons with vestibular disorders.

The purpose of this study was to determine the sensitivity and specificity of the Timed "Up & Go" (TUG) and Dynamic Gait Index in identifying self-reported fallers among persons with vestibular dysfunction. One hundred three patient charts were included from a tertiary vestibular physical therapy practice. The patients ranged in age from 14-90 years and had vestibular diagnoses, falls reported in the patient chart, and completed the TUG and/or the Dynamic Gait Index (DGI). Thirty-one persons reported falling one or more times in the previous 6 months during their initial assessment. Persons who took longer than 13.5 seconds to perform the TUG test were 3.7 times more likely to have reported a fall in the previous 6 months. Those persons with scores less than or equal to 18 on the DGI were 2.7 times (p = 0.03) more likely to have reported a fall in the previous 6 months. The sensitivity of the DGI at 18 or less was 70% and the specificity was 51%. People who scored greater than 11.1 seconds on the TUG were 5 times (p = 0.001) more likely to have reported a fall in the previous 6 months. Sensitivity (80%) and specificity (56%) were calculated for TUG scores of greater than 11.1 seconds. The TUG and the DGI appear to be helpful in identifying fall risk in persons with vestibular dysfunction. Slower scores on the TUG (> 11.1 seconds) and lower scores on the DGI (18) correlated with reports of falls in persons with vestibular dysfunction.

Accidental Falls↗

The effect of age on vestibular rehabilitation outcomes.

OBJECTIVE: The purpose of the retrospective chart review was to compare vestibular rehabilitation outcomes in young versus older adults. STUDY DESIGN: Retrospective matched design. METHODS: Twenty-three persons with vestibular disorders aged 20 to 40 years were matched by gender, vestibular diagnosis, and vestibular function test results to 23 older adults aged 60 to 80 years. The patients were treated with a custom-designed physical therapy exercise program. Patients completed the Dizziness Handicap Inventory, the Activities-Specific Balance Confidence (ABC) scale, and the Dynamic Gait Index; number of falls; and rated the severity of their dizziness. The two-sample test, the Mann-Whitney test, and McNemar's test for correlated proportions were used to determine whether there was a difference in scores between the two age groups at the beginning and end of physical therapy. RESULTS: During the initial evaluation, older adults reported having statistically greater space and motion discomfort and more severe symptoms on a scale of 0 to 100. Younger adults had more impaired DGI scores and a higher proportion of caloric testing abnormalities. After rehabilitation, overall improvement was seen in both the younger and older populations. There were no statistical differences between the two groups on the DHI, the DGI, reported symptoms at discharge, or number of falls. When only the complete matched-pair data were analyzed, there were no statistically significant differences between the age groups in the proportion of patients demonstrating clinical improvement. CONCLUSION: Age does not significantly influence the beneficial effects of vestibular rehabilitation for persons with vestibular disorders.

Adult↗