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Biomedical subjects

Grzegorz Kamiński

Publications and source records attributed to Grzegorz Kamiński.

9 recordsLinked to original sources
PubMed2006

[Detection of patients at risk for paroxysmal atrial fibrillation (PAF) by signal averaged P wave, standard ECG and echocardiography].

UNLABELLED: The aim of this study was to evaluate whether analysis of signal averaged P wave, together with left atrial diameter (LA) and P wave duration in surface ECG lead II (PII) allow to predict the risk of PAF. MATERIAL AND METHODS: Patients with coronary heart disease and/or hypertension were examined (n=145). They were divided into two groups 110 patients with PAF were compared with 35 patients without PAF Age (60,5 vs. 57,4 years) and LA size (39,8 vs. 3,7 mm) were similar in two groups. RESULTS: The root mean square voltage (RMS) for the last 10,20, 30 ms were calculated and for all of the filtered P wave (RMSW) were measured RMS ratio (RMSR) were calculated according to RMSW/ RMS20. Filtered P wave duration (PWD) and difference befteen PWD and P II (PWD-PII) were established. Most of the analyzed parameters were statistically significant (p<0,05). The statistical analyses made it possible to outline the score index evaluating how PAF reacts parameters. CONCLUSIONS: Score index evaluating of the PAF occurrence and its influence is statistically significant with sensitivity 86%, specificity 83,5% and index positive predictor 82,7% and index negative predictor 83,7%. The most significant parameters which detect the patients with the occurrence of PAF are PWD > or =130ms, RMS20<3, microV, RMS10<2,2 microV and PWD-PII > or =40 ms.

Amiodarone↗
PubMed2006

[The influence of weather conditions on the occurrence of paroxysmal atrial fibrillation].

UNLABELLED: The effect of the changing weather conditions on the incidence of the paroxysmal atrial fibrillation (PAF) has not been documented before. MATERIAL AND METHODS: This analysis retrospectively assessed the influence of the weather conditions on 1153 PAF cases over the period of 10 years. The average age of the studied population was 64.9 +/- 9.2 years. There was 60% males in the group. The majority (84%) had an existing heart disease, the remaining part was diagnosed as the lone PAF. RESULTS: The following factors favoured the FAP occurrence: high air temperature (> 25 Centigrade) for more than 3 days, low temperature (< 8 Centigrade), water vapor pressure > 16.5 kPa, accelerated increase of the air pressure > 8hPa over 2 days. CONCLUSIONS: The following weather conditions such as: temperature, air humidity and pressure have a definite impact on the occurrence of the paroxysmal atrial fibrillation episodes in 87% of patients especially those with co-existing coronary heart disease, hypertension or older age.

Aged↗
PubMed2006

[Usefulness of measurement of glucose and glycosylated hemoglobin levels in patients with acute coronary syndrome as predictors of number of stenotic coronary arteries as shown in coronary arteriography].

UNLABELLED: Data on corelation between diabetes and multivessel coronary disease have been documented. The aim of the study was to estimate usefulness of measurement of glucose and glygosylated haemoglobin levels in patients with acute coronary syndrome as a predictors of number of stenotic coronary arteries shown in coronary arteriography. METHODS: We examined 386 patients (mean age was 61 +/- 10, men/ women 263/123). All of them underwent coronary angiography 81 patients (21%) had diabetes. A routine examination included age, sex, clinical state, BMI, WHR, plasma lipids, coagulative parameters, glucose level, HbA1c level, urea, creatine, C-reactive protein levels, blood pressure and heart failure traits. RESULTS: There were 11.2% patients without any changes in coronary arteries, 28.4% patients with one or two stenotic arteries and 60.4% patients with more than two stenotic coronary arteries. We observed that glucose and HbA1c levels were significantly higher in group without any changes vs group with one or two stenotic vessels and more than two stenotic vessels. The differences were still statistically significant in patients with diabetes and HbA1c over 6.2%. CONCLUSION: In conclusion, measurement of glucose and glycosylated haemoglobin levels in moment of diagnosis acute coronary syndrome can have prognostic estimation of number of stenotic arteries.

Acute Disease↗
PubMed2005

[Left ventricular function in gated single photon emission computed tomography (GSPET) in patients with myocardial infarction subjected to thrombolysis or primary PTCA].

Primary Percutaneous Transluminal Coronary Angioplasty (PTCA) is increasingly common method of treatment patients with acute myocardial infarction. The aim of the study was to assess the left ventricular function in patients with myocardial infarction subjected to thrombolysis or primary PTCA. Gated Single Photon Emission Computed Tomography was performed in 40 patients 6 months after myocardial infarction treated either with thrombolysis or primary PTCA. Left ventricular ejection fraction (LVEF), left ventricular enddiastolic (LVED) and systolic (LVES) volumes were analysed both at rest and after stress. Six months after myocardial infarction LVEF was significantly greater and LVED, LVES volumes smaller in patients treated with primary PTCA in comparison to patients treated with thrombolysis. The above observation suggests that patients subjected to primary PTCA might have better functional outcome in comparison to matched patients treated with thrombolysis after 6 months post myocardial infarction.

Adult↗
PubMed2005

[Degenerative valvular and left ventricle structural changes in echocardiography in patients with rheumatoid arthritis].

UNLABELLED: The disproportion between absence of clinical manifestations of circulatory system involvement and serious lesions in the heart found on post mortem examinations, more frequently diagnosed congestive circulatory failure and also higher mortality rate of patients with rheumatoid arthritis (RA), encouraged the authors to study the subject. THE AIM OF THE STUDY: Echocardiographic assessment of the effect of rheumatoid process on the heart in patients with RA without clinically overt features of heart disease. MATERIAL AND METHODS: The study was conducted in 50 patients with RA diagnosed on the basis of the American College of Rheumatology (ACR) criteria and in 50 persons matched with the patients with respect to age, gender, body area and body mass index, heart rate and arterial pressure. Persons with manifestations and/or history of cardiovascular diseases were excluded from the study. RESULTS AND CONCLUSION: The authors found that: in rheumatoid arthritis, the involvement of the heart by the pathological process is manifested as degenerative changes of valve leaflets, and these lesions correlate with interventricular septum thickness and the mass and mass index of the left ventricle.

Aged↗
PubMed2004

[Renal osteodystrophy as a cause of false positive result of whole body scintigraphy in a patient with differentiated thyroid cancer].

We demonstrated the case of coexistence of secondary hyperparathyroidism in the course of irreversible renal failure and differentiated thyroid carcinoma diagnosed at the time of parathyroidectomy. Changes in skeletal system caused by secondary hyperparathyroidism resulted in false positive result of whole body scintigraphy and required differentiation with bone metastases of thyroid cancer. Therefore, the diagnostic tests of thyroid gland are necessary before parathyroidectomy in patients with secondary hyperparathyroidism.

Adult↗
PubMed2003

[Left ventricular function in rheumatoid arthritis patients].

BACKGROUND: The disproportion between the absence of clinical manifestations of circulatory system involvement and serious lesions in the heart found on post mortem examinations, more frequently diagnosed congestive circulatory failure and also higher mortality rate of patients with rheumatoid arthritis (RA), encouraged the authors to study the subject. THE AIM OF THE STUDY WAS: Echocardiographic assessment of the effect of rheumatoid process on left ventricular structure, and systolic and diastolic function in patients with RA without clinically overt features of heart disease. METHODS: The study was conducted in 50 patients with RA diagnosed on the basis of the ACR criteria and in 50 persons matched with the patients with respect to age, gender, body area and body mass index, heart rate and arterial pressure. Persons with manifestations and/or history of cardiovascular diseases were excluded from the study. RESULTS: The authors found that: in RA, the involvement of the myocardium by the pathological process was manifested as increased wall thickness, increased mass and mass index of the left ventricle with impairment of its diastolic function and normal systolic function. With progressing rheumatoid process, left ventricular systolic function impairment was observed. Left ventricular diastolic dysfunction in the course of rheumatoid arthritis usually was not manifested clinically.

Arthritis, Rheumatoid↗
PubMed2002

Autonomic nervous system and left ventricular hypertrophy in essential hypertension.

BACKGROUND: Patients with essential hypertension (EH) and left ventricular hypertrophy (LVH) have an increased risk of cardio-vascular complications. Alterations in the autonomic nervous system (ANS) activity may play a role in the development of serious cardiac arrhythmias and mortality in these patients. AIM: To examine the activity of ANS in patients with established EH in relation to the presence of LVH. METHODS: The study group consisted of 70 subjects: 50 patients with untreated EH (mean age 44.4+/-12.7 years, 28 patients without LVH and 22 with LVH), and 20 age-matched healthy volunteers. ANS reactivity was assessed using heart rate variability (HRV) analysed during tilt table testing at 60 degrees. The following 5-min time-periods were analysed: (A) before tilting (supine position), (B) initial period of tilting, (C) last 5 min of tilting, and (D) immediately after completion of tilt test (after return to supine position). RESULTS: Patients with EH without LVH had a higher increase of LF/HF values (period B versus period C) compared with controls (p<0.05). The change from tilt to supine position caused significantly lower change in lnHF values in patients with EH and LVH than in controls (p<0.01) or patients with EH without LVH (p<0.005). In patients with EH and LVH a significant correlation between HF and LVmass/height (r=-0.5, p<0.01) was noted. Compared with healthy controls, patients with EH and LVH had significantly lower HRV parameters [lnLF values were significantly lower in all analysed periods, (p<0.05), and lnHF - during period D, (p<0.01)] whereas LF/HF ratio assessed during period D was significantly higher (p<0.05). CONCLUSIONS: In patients with EH without LVH a relative dominance of sympathetic activity is present. LVH in EH leads to a decrease in vagal drive and progressive inhibition of parasympathetic activity, both of which decrease HRV. These changes may play an important role in the electrical instability of hypertrophied myocardium.

Journal Article↗