Biomedical subjects

Guering Eid-Lidt

Publications and source records attributed to Guering Eid-Lidt.

3 recordsLinked to original sources

PubMed2004

Endovascular treatment of the subclavian artery: stent implantation with or without predilatation.

The endovascular treatment of subclavian artery (SA) lesions is less invasive than open surgical repair, with a low rate of complications. We report our experience in 89 subclavian obstructive lesions (n = 86) treated with stenting: 76 (85.3%) stenoses and 13 (14.6%) total occlusions. The left side was most frequently involved (83.1%), localized at the prevertebral segment in 91%. Technical success was obtained in 83 (93.3%) cases, 100% in stenotic lesions and 53.8% in total occlusions. There were nine global complications (10.1%): five (5.6%) at site of puncture, two distal embolization (2.2%), and two (2.3%) major events. The long-term follow-up was 3.51 +/- 1.98 years, during which time 13 (16.8%) restenoses and 2 (2.6%) reocclusions were noted. Subgroup analysis of patients with stenting after predilatation versus direct stenting technique showed in-hospital complications only in the first group, with a restenosis rate of 28.5% vs. 4.7%, respectively (P = 0.003). We consider stenting for SA obstructive lesions the first therapeutic option.

Aged↗

PubMed1999

Treatment of coronary artery aneurysms by percutaneous sealing with bovine-pericardium-covered stents.

The clinical significance of coronary artery aneurysms is briefly discussed. Until recently, surgical excision was the only treatment available. Single-case reports have documented aneurysm exclusion with vein-covered stents using 10 or 11 F. guiding catheters. This paper reports four patients with coronary artery aneurysms which were successfully excluded with the use of a novel pericardium-covered stent which is less invasive and shortens procedure time compared with the use of an autologous vein-grated stent and can be deployed using 8 F. or 9 F. guiding catheters. Short-term (five- to eight-month) clinical follow-up has been event-free in all patients, and in three patients six-month follow-up angiography has shown insignificant luminal loss.

Journal Article↗

PubMedDate not supplied

[Coronary collateral circulation].

Coronary collaterals are anastomotic connections without an intervening capillary bed between portions of the same coronary artery and between different coronary arteries. The main determinants of coronary collateral circulation are preinfarction angina, severity of coronary artery disease, significant pressure gradient and an increase in shear stress. In presence of pressure gradient the blood flow is redistributed through the preexistent arterioles that connect a high-pressure with a low-pressure area. The consequence is an increased flow velocity and therefore increased shear stress in the collateral arteries, which leads to a marked activation of the endothelium with the subsequent morphological changes, vascular remodeling and activation of growth factors involved in angiogenesis and arteriogenesis. Well-developed coronary collateral circulation can be observed in 25% to 37% of patients with one vessel coronary artery disease and in 74.7% patients with extensive disease. Recruitable collaterals can be evaluated by performing coronary angiography, a qualitative or semiquantitative technique and by measurement of pressure and velocity in distal vascular beds (quantitative technique). Demonstration of well-developed collaterals in patients with angina pectoris or myocardial infarction has been associated with limited infarct size, improved ventricular function, less ventricular aneurysm formation and improved in-hospital and long-term survival.

Collateral Circulation↗