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Biomedical subjects

Guido Virgili

Publications and source records attributed to Guido Virgili.

6 recordsLinked to original sources
PubMed2005

Percutaneous sequential bacillus Calmette-Guèrin and mitomycin C for panurothelial carcinomatosis.

A 59 year old male presented with a 4 month history of lower urinary tract symptoms. Exhaustive urological investigations revealed papillary tumors and carcinoma in situ extending from the prostatic urethra, throughout the bladder, up both ureters and into the renal pelves. Tumors were resected where possible and then bacillus Calmette-Guèrin (BCG) and mitomycin C (MMC) were infused sequentially through bilateral nephrostomy tubes for a total of six BCG and three MMC instillations. Follow up 1 month post treatment demonstrated a complete response which persisted for 2 years. Then there appeared a solitary papillomatous recurrence in the bladder which was successfully resected. Side effects were the occasional fever and BCG induced granulomatous prostatitis which slowly resolved. In conclusion, sequential BCG/MMC instillations were effective treatment for widespread panurothelial carcinomatosis.

Adjuvants, Immunologic↗
PubMed2004

Leiomyoma of the epididymis and testicular adnexa: apropos of 3 cases.

The intrascrotal benign tumours are rare and are generally defined as arising between didymis and spermatic cord. Among the benign tumours of the epididymis and testicular adnexa, leiomyoma is second most common. Three cases of intrascrotal leiomyoma are reported: two originating from the epididymis and one from the epididymis and tunica vaginalis.

Adult↗
PubMed2004

Radical prostatectomy as unique chance for huge prostatic stones.

Prostatic calculi occur very often in men, but exceptionally they cause an almost total destruction of the prostatic parenchyma. Preferred treatment in order to obtain complete resolution is either transurethral resection or suprapubic simple prostatectomy. We report for the first time a radical prostatectomy as a unique chance for huge prostatic stones in a 56-years old man with severe urinary symptoms. We perform a retropubic radical prostatectomy using a nerve sparing technique. There were no intraoperative or postoperative complications. Though radical prostatectomy is an invasive approach to treat a young man affected by prostatic stones and without prostate cancer, we chose to perform it because of the impossibility to obtain complete recovery with transurethral or suprapubic simple prostatectomy.

Calculi↗
PubMed2003

Cavernous hemangioma of the renal hilum presenting as an avascularized solid mass.

Hemangiomas are slowly growing benign vascular tumours which rarely involve the kidney. They usually occur in the mucosa or subepithelial tissue of the pelvis, in the pyramid of the kidney and in the cortex. We report a case of cavernous hemangioma presenting as a solid, paradoxically avascular mass of the right renal hilum.

Adult↗
PubMed2002

Acute lumbago and sciatica as first symptoms of focal xanthogranulomatous pyelonephritis.

Xanthogranulomatous pyelonephritis (XGP) is a rare inflammatory disease of the kidney, presenting in a diffuse or focal form. The preoperative diagnosis of XGP is made only in 10% of the cases because neither the clinical nor the radiological presentation are specific and could be confused with renal tumors, thus deserving the name of 'great imitator'. We report a case of focal XGP in a middle-aged man presenting with acute lumbago and sciatica, an unusual clinical presentation.

Acute Disease↗