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Guo He

Publications and source records attributed to Guo He.

3 recordsLinked to original sources

Novel Ti-base nanostructure-dendrite composite with enhanced plasticity.

Single-phase nanocrystalline materials undergo inhomogeneous plastic deformation under loading at room temperature, which results in a very limited plastic strain (smaller than 0-3%). The materials therefore display low ductility, leading to catastrophic failure, which severely restricts their application. Here, we present a new in situ-formed nanostructured matrix/ductile dendritic phase composite microstructure for Ti-base alloys, which exhibits up to 14.5% compressive plastic strain at room temperature. The new composite microstructure was synthesized on the basis of the appropriate choice of composition, and by using well-controlled solidification conditions. Deformation occurs partially through dislocation movement in dendrites, and partially through a shear-banding mechanism in the nanostructured matrix. The dendrites act as obstacles restricting the excessive deformation by isolating the highly localized shear bands in small, discrete interdendritic regions, and contribute to the plasticity. We suggest that microscale ductile crystalline phases might therefore be used to toughen nanostructured materials.

Alloys↗

[Irradiated porcine skin impregnated with fluorine and silver covered by autogenous granule skin graft for treating severe burn injury].

OBJECTIVE: To study the feasibility of using irradiated porcine skin impregnated with fluorine and silver covered by autogenous skin granule graft in the treatment of severe burn injury. METHODS: Autogenous split-thick skin grafts were cut into small pieces (<1 mm3), which were transferred onto the sheet of porcine skin mounted with a layer of Xinnaxing ointment (2 mm in thickness). After eschar removal, the burn wound was covered with the prepared porcine skin, sutured and fixed with small holes at the lower site for drainage. The growth of autogenous granule skin was then observed and the criteria for therapeutic effect evaluation drafted. RESULTS: The layer of Xinnaxing ointment on the the porcine skin improved the adhesion of the autogenous small skin grafts, therefore full use could be made of the donor skin source. In the 15 patients receiving this treatment, the graft-covered area was (12.3+/-3.5) % that of the wound, with the donor-recipient area ratio of 1: (11.0+/-2.7) and subsequent healing time of 27.5+/-5.5 d. Primary healing was achieved in 9 cases, and secondary healing in 6, demonstrating similar clinical effect to that of allo-skin grafting. CONCLUSION: The method is easy and economic, which saves autogenous skin source and produces satisfactory clinical effect.

Adult↗

[Clinical application of meshed porcine acellular dermis xenograft with split-thickness skin autograft].

OBJECTIVE: To observe the clinical effect of meshed porcine acellular dermis xenograft in conjunction with split- thickness skin autograft in the treatment of full-thickness skin burns and the wound after scar resection. METHOD: Sixteen patients receive the treatment with the skin grafts and the effects of one- and two-stage graftings were compared. RESULTS: In the patient group receiving one-stage grafting, 100% survival rate of the grafts was achieved in 4 cases, 95% in 3 cases, and 80% in 1 case. In two-stage grafting group, 100% survival rate of the grafts was achieved in 5 cases and more than 95% in 3 cases. No cases needed secondary grafting. During the follow-up of the patients for 6 months to 2 years, all the grafts assumed basically normal exterior appearance and texture without obvious scar formation. CONCLUSIONS: The combination of meshed porcine acellular dermis xenograft and split-thickness skin autograft was ideal for repairing full-thickness skin burns, for which one- stage grafting is both simple and practical.

Adolescent↗