Biomedical subjects

Gyöngyi Gesztelyi

Publications and source records attributed to Gyöngyi Gesztelyi.

3 recordsLinked to original sources

PubMed2006

Determinants of disability in everyday activities differ in primary and cervicogenic headaches and in low back pain.

The aim of this study was to test whether the association between disability and depressive symptoms in patients with cervicogenic headache is similar to that found in primary headaches or to the pattern found in low back pain. During a 2-year period, 716 consecutive patients with the clinical diagnosis of cervicogenic headache (n=182), low back pain (n=116), migraine (n=231), tension-type headache (n=176), and cluster headache (n=11) filled in the Beck Depression Inventory (BDI). Disability was scored by the migraine disability score questionnaire reflecting the number of days with lost or decreased work, household and social activities. Non-parametric tests and multiple general regression were used for statistical analysis. In multivariate testing, significant independent determinants of disability were pain frequency, pain intensity and the severity of depressive symptoms in migraine and tension-type headache; pain frequency and the BDI score in cervicogenic headache, and pain frequency alone in low back pain. Disability is related to pain frequency in all pain syndromes evaluated in the present study. The level of disability is associated with the severity of pain only in primary headaches, but not in pain syndromes of vertebral origin (cervicogenic headache and low back pain). Disability is associated with the severity of depressive symptoms in all headache types but not in low back pain. Both the location and the etiology of pain have importance in determining the interrelationship between pain characteristics, depression and disability.

Activities of Daily Living↗

PubMed2005

[Headache as a chief subject in the Hungarian medical literature].

BACKGROUND: Less than 1.2% of papers published in the first 50 volumes of the journal Clinical Neuroscience/Ideggyógyászati Szemle--the major official journal of Hungarian neurologists--focused on headache despite the fact that headache is among the most frequent complaints in neurological consultations. In the current study the authors evaluated the presence of headache as the main topic in articles of the Hungarian medical literature. METHODS: They identified full publications on headache by handsearching all volumes of the journal Clinical Neuroscience/Ideggyógyászati Szemle from 1950 till the end of 2003. Electronic searches were performed to find Hungarian papers focusing on headache using the bibliographic databases of the Hungarian National Library of Healthcare (Hungarian Medical Bibliography, HMB) and the American National Library of Medicine of the National Institutes of Health (Medline and Oldmedline). Results of handsearch and electronic searches were cross checked for the journal Clinical Neuroscience/Ideggyógyászati Szemle. RESULTS: Of the 2618 full papers published in Clinical Neuroscience/Ideggyógyászati Szemle headache was the main topic in 32 articles (1.2%), most of them published after 1985. The electronic search of the HMB resulted in 132 documents in 41 journals, whereas using the PubMed search engine, they identified 66 Hungarian papers on headache. Migraine was the most frequent topic of interest in papers found by all three searches. The HMB search identified all headache articles published after 1990 in Clinical Neuroscience/Ideggyógyászati Szemle which were identified by handsearch. The Oldmedline, database contained four of the seven papers identified by handsearch from 1954-1964. After 2002, the start of indexing Clinical Neuroscience/Ideggyógyászati Szemle in the Medline, the only article identified by handsearch was also found by the electronic search. CONCLUSION: After the lack of interest until the mid-1980-ies, headache became a frequent topic in the Hungarian medical literature. Bibliographical data of articles on headache published after 1990 can be identified by electronic searches of the Hungarian and international bibliographic databases using carefully constructed but simple search strategies. An increasing presence of Hungarian headache research was found in international journals in the last two decades.

Bibliometrics↗

PubMed2004

[Primary headache and depression].

Primary headaches--mainly tension-type headache and migraine--affect a significant portion of the population. Depression is also highly prevalent. The co-existence of a primary headache and depression in the same patient therefore might be a coincidence due to the high prevalence of these conditions, but there might be a causal relationship between them, or headaches and depression might have a common background. This review of the literature summarizes the features of the relationship between primary headaches and depression. Depression is more prevalent in headache patients than in the headache-free population. Prospective epidemiological studies suggest a common genetic, biochemical or environmental background behind primary headaches and depression. This theory is supported by the role of the same neurotransmitter systems (mostly serotonin and dopamine) in headaches as well as in depression. Comorbid depression is associated with female gender, higher age, and higher frequency of headaches. Most depression inventories--questionnaires used to screen for the severity of depressive symptoms--contain transdiagnostic items, therefore their use in their original form is limited in organic diseases: due to the somatic items they might overestimate the severity of depression. When examining a headache patient special attention should be paid to the recognition of comorbid depression. The diagnosis of suspected mood disorder could be supported by using simple screening methods, such as the original or the abbreviated versions of standard depression inventories, but the final diagnosis of major depression needs psychiatric evaluation. Quality of life of the headache patient is affected not only by the characteristics of pain (frequency, duration, severity) but also by the disability caused by headache and the associating mood disorder. Recognizing coexisting mood disorder and disability helps to make the best treatment choice for the acute and preventive treatment of headaches. For the dual effect, in headache and comorbid depression, antidepressants should be the first choice among the medications proved to be effective in the prevention of primary headaches. Of the antidepressants the effect of tricyclic compounds (primarily amitriptyline) has been proven for the prevention of both tension-type headache and migraine. Further studies are needed regarding antidepressants with selective serotonin reuptake inhibitor (SSRI) effect.

Antidepressive Agents↗