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Gyanendra K Sharma

Publications and source records attributed to Gyanendra K Sharma.

4 recordsLinked to original sources
PubMed2005

Assessment of test repeatability of arterial stiffness index.

BACKGROUND: Increased arterial stiffness is an early indicator of vascular disease. Several methods may be used to determine arterial stiffness. One method obtains an arterial stiffness index from the vascular dynamics of oscillometric-derived brachial artery pressure. METHODS: To determine the test-retest repeatability of the CardioVision MS-2000, 47 healthy hospital employees had five consecutive measurements of arterial stiffness index measured after a 5-10 min period of rest and then repeated after an average of 146.8 days. Their mean age was 37 years and 71% were women. RESULTS: The mean arterial stiffness index was 39.6+/-9.7 and 37.2+/-10.5 mmHg x10 (P=0.22) for the first and second time period, respectively. We computed an intraclass correlation coefficient of 0.31 and 0.33 for the first and second time periods, which is the measure of consistency or agreement of arterial stiffness index values within cases. The intraclass correlation coefficient for systolic blood pressure, diastolic blood pressure, heart rate and arterial stiffness index were 0.68 (P=0.0001), 0.70 (P=0.0001), 0.35 (P=0.02) and 0.25 (P=0.08), respectively. CONCLUSION: The results of this study suggest poor test-retest repeatability if consecutive measurements are used. The intraclass correlation coefficient, however, could be improved by eliminating the highest and lowest value from a set of measurements.

Adult↗
PubMed2002

The relationship between somatic and PTSD symptoms among Bhutanese refugee torture survivors: examination of comorbidity with anxiety and depression.

Previous research has indicated a relationship between posttraumatic stress disorder (PTSD) and somatic complaints. We examined whether this relationship is a result of shared comorbidity with anxiety and depression. Local doctors interviewed a random, community sample of 526 tortured and 526 nontortured Bhutanese refugees living in U.N. refugee camps in Nepal. The interview covered demographics, torture, somatic complaints, and PTSD, depression, and anxiety measures. Number of PTSD symptoms, independent of depression and anxiety, predicted both number of reported somatic complaints and number of organ systems involving such complaints. Physicians need to screen for PTSD when survivors of extreme stressors present nonspecific somatic complaints.

Adult↗
PubMedDate not supplied

Characteristics of patients with cervical spinal injury requiring permanent pacemaker implantation.

Acute cervical spinal cord injury frequently results in bradydysrhythmia, which may lead to hypotension and asystole. Such symptoms are more common in the first 2 weeks after the injury. Treatment modalities include atropine, epinephrine, aminophylline, and pacemaker insertion. The criteria for pacemaker use in this population are not well defined. We describe characteristics of 3 patients who required permanent, transvenous pacemaker implantation for recurrent symptoms. In 2 of the 3 patients, transcutaneous pacing failed to provide adequate protection. Transcutaneous pacemakers are not reliable, as was the case of these patients, and early consideration for transvenous pacemaker insertion may be indicated, especially in hemodynamically unstable patients. In this report, all 3 patients required permanent pacemaker implantation.

Adult↗