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Biomedical subjects

H A Allen

Publications and source records attributed to H A Allen.

At least 37 records · Page 2Linked to original sources

Do positive symptom and negative symptom subtypes of schizophrenia show qualitative differences in language production?

The present study examined a prominent symptom subtype conception of the psychopathology of schizophrenia. It analysed the presumed dichotomy between hallucinations, delusions and formal thought disorder as positive symptoms and flattening of affect and poverty of speech as negative symptoms, and tested predictions concerning the nature of the mediating processes of positive and negative symptoms. Four different analyses were applied to the transcripts of speech produced by 9 normals, 10 chronic schizophrenics with only positive symptoms of whom 7 had incoherence of speech, and 9 chronic schizophrenics with only negative symptoms of whom 4 had poverty of speech. The conception of the nature of the mediating processes of positive and negative symptoms was not supported by the results. Further, a clear dichotomy between positive and negative symptom groups was not shown to exist, because positive speech disorder and negative speech disorder did not follow the presupposed dichotomy. Thus, contrary to existing conceptions of speech disorder in schizophrenia, both positive and negative speech disorder are marked by poverty of thought, as measured by the production of fewer and shorter ideas and lower speech variability.

Adult↗

Selective retrieval and free emission of category exemplars in schizophrenia.

In a free emission task, normals, chronic schizophrenics with only positive and those with only negative symptoms generated as many exemplars from natural language categories as they could in three minutes. While the overall output level of both schizophrenic groups was lower than that of the normals, neither showed intrusions of unrelated words, and the temporal distribution of the output was marked by a clustering pattern inconsistent with a selective attention deficit hypothesis. The schizophrenics with negative symptoms tended to produce consistently smaller clusters than the normals and the schizophrenics with positive symptoms, implicating a specific retrieval constriction. The relationship of this to the major negative symptom poverty of speech is discussed.

Adult↗

Basal ganglia calcification in the neonate.

Calcification of the basal ganglia developed following intracranial hemorrhage in a neonate recovering from severe perinatal asphyxia. Cranial computed tomography is useful in demonstrating the anatomic distribution of dystrophic calcification in regions previously involved by hemorrhage. The demonstration of hemorrhage or hemorrhagic infarction with CT may help to verify the association of basal ganglia calcification with birth anoxia.

Adult↗

Dichotic monitoring and focused versus divided attention in schizophrenia.

The target detection performance of normals, chronic schizophrenics with positive symptoms and those with negative symptoms was compared in focused and divided attention conditions. The focused condition involved the monitoring of one, and the divided condition the monitoring of both, of the dichotically presented word lists. The amount and rate of list presentations were held constant across the conditions in an attempt to separate attentional from difficulty and capacity factors. Results showed that while the overall performance of both schizophrenic groups was lower than that of the normals, their performance change from the focused to the divided attention condition did not differ from that of the normals. These results do not support a schizophrenic selective attention deficit hypothesis.

Attention↗

Loneliness and alcoholism: a study of three groups of male alcoholics.

Three groups of alcoholics at different stages of recovery were tested for loneliness with the Sisenwein Loneliness Scale. The groups consisted of alcoholics going through detoxification (acute), alcoholics in outpatient treatment who had had at least two drinking episodes in the previous 6 months (chronic), and alcoholics having at least 1 year of sobriety (recovering). It was hypothesized that the acute group would exhibit more loneliness than the chronic group, who would in turn demonstrate more loneliness than the recovering group. Results showed that acute group to demonstrate significantly (p less than .01) more loneliness on the Sisenwein (mean = 134.4) than the recovering group (mean = 54.6). The chronic group (mean = 91.0) was not significantly different than the others at the p less than .01 level, but the mean score did fall in the expected direction.

Adult↗

Citrobacter koseri. II. Serological and biochemical examination of Citrobacter koseri strains from clinical specimens.

165 strains of Citrobacter koseri isolated from clinical specimens were studied and their biochemical reactions determined. They were examined serologically by means of a scheme consisting of 14 O antigens. The sources of the clinical specimens were tabulated and the epidemiological information was summarized. The clinical significance of these findings is discussed.

Antigens, Bacterial↗

Shigella dysenteriae and Shigella boydii in England and Wales during 1972 and 1973.

During 1972 and 1973 the Salmonella and Shigella Reference Laboratory examined 133 strains of Shigella dysenteriae and Shigella boydii isolated from patients in England and Wales. Of those infected 89 had recently travelled abroad and a further seven had been in close contact with travellers recently returned to this country. Though these subgroups were of little numerical significance they are of considerable epidemiological interest. The increase in tourism from the British Isles to North Africa and Asia is likely to lead to an increased incidence of infections due to these organisms, both in travellers infected abroad and in their contacts within the British Isles.

Cross Infection↗