The progressive decrease in the proportion of blood donors with antibody to the human immunodeficiency virus (HIV)
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Biomedical subjects
Publications and source records attributed to H A Perkins.
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Review of the dates of prior blood donation by persons later reported to have AIDS demonstrated that most of them had ceased donating blood in 1983. The results indicate that self-exclusion policies were effective.
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The preparation of leukocyte-poor cell masses (LPCM) by saline washing with the IBM 2291 Blood Cell Processor was investigated. Units to be washed were preferentially selected from short-dated units to reduce outdating. LPCM had a mean of 0.34 X 10(9) WBC (90% WBC removal) with 87.8 per cent RBC recovery. At least 50 per cent of the LPCM prepared used blood that was salvaged from typically discarded units. Febrile transfusion reactions were prevented in alloimmunized patients with this product. Cell washing with the IBM Blood Cell Processor can prepare LPCM from blood of any storage date to meet American Association of Blood Banks (AABB) standards.