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Biomedical subjects

H A Peterson

Publications and source records attributed to H A Peterson.

16 recordsLinked to original sources

Physeal injuries of the distal humerus.

Physeal injuries of the distal humerus comprise approximately 10% of all physeal injuries. Diagnosis of these injuries at a young age before the ossification centers have ossified and become visible radiographically is difficult. Poor outcome of distal humeral physeal injuries is not uncommon and can be best prevented by knowledge of anatomy and the use of all appropriate imaging techniques. The focus of this article is to correlate anatomy at different ages with the occurrence of specific injuries.

Adult

Premature partial physeal arrest. Diagnosis by magnetic resonance imaging in two cases.

The management of premature physeal arrest requires accurate assessment of not only the location but also the extent of the bar. Numerous imaging techniques are available to evaluate the physis. Multiplanar tomography has proven to be the most precise method. The utility of magnetic resonance imaging (MRI) of physeal bars has not been demonstrated. This article presents MRI results in two cases of physeal bars. MRI provides a means of assessing physeal bar formation with an accuracy approaching that of multiplanar tomography. In certain instances, its efficacy may exceed that of tomography, specifically when the physis cannot be properly oriented for tomographic evaluation, when more planes are desired, and when radiation exposure is thought to be excessive. With improvement of its capabilities and availability (which may also reduce cost), it may become the diagnostic imaging technique of choice.

Ankle Joint

Markedness analysis of phonemic substitution errors in apraxia of speech.

The phonemic substitution errors of ten apractic speakers were analyzed to investigate the effects of markedness on speech production patterns. Results revealed that: more errors were produced on phonemes high in markedness; more changes in markedness were from marked to unmarked than unmarked to marked; and errors and directional changes in markedness were positively correlated with ease of articulation. The findings were interpreted as a systematic effort by the apractic speakers to reduce the complexity of articulatory gestures required to produce phonemes.

Aged

Fractures of the proximal tibial epiphysis.

Fractures of the proximal tibial epiphysis are rare. A series of twenty-eight fractures classified according to the Salter-Harris method showed that nine were Type II and eight, Type IV. Lawn-mower injuries, a previously unreported mode of injury for this fracture, caused five of the eight Type-IV fractures and were associated with the worst prognosis by far. Two Type-V fractures in the proximal tibial epiphysis, previously unreported, are described.

Accidents, Home

Leg aches.

In the investigation of children with leg aches, it is essential to identify those with demonstrable underlying organic diseases. Growing pains is a poorly named, nebulous entity that can be diagnosed only by exclusion. The greatest diagnostic error is to make a diagnosis of growing pains while overlooking some serious underlying condition.

Child

Effects of selected linguistic variables on apraxia of speech.

Ten adults with apraxia of speech responded to sentences of an article (pronoun) + noun + verb + article (pronoun) + noun design. Each sentence was presented and then re-presented with the noun in Noun Phrase 1 (NP1) or Noun Phrase 2 (NP2) omitted. The subjects' task was to orally produce the omitted word. Sentences were either active or passive and the omitted noun was a concrete, abstract, or nonsense word. Results revealed significantly more errors in NP1 than NP2, more errors on nonsense and abstract nouns than on concrete nouns, and more errors on passive than on active voice sentences. Linguistic bases for these findings are discussed.

Adult

Failure of inactivation of Duchenne dystrophy X-chromosome in one of female identical twins.

Duchenne muscular dystrophy manifested in one of girl twins. The twins were monozygous on the basis of red cell and HL antigens and skin graft compatibility. Karyotyping, including banding techniques, showed a normal number of chromosomes and a normal configuration of the X-chromosome in both twins. The twins were identical in appearance until symptoms of Duchenne dystrophy developed in one at age 4 years. The maternal uncle had classic Duchenne dystrophy; the mother and the nonmanifesting twin showed evidence of being heterozygous for Duchenne dystrophy. The phenotypic difference in monozygous twins is readily explained by lyonization of the X-chromosome after twinning has occurred. The findings substantiate the existence of Duchenne dystrophy manifesting in females with normal karyotypes.

Child

Osteomyelitis following puncture wounds of the foot in children.

Review of the laboratory and clinical findings and treatment of eight patients with osteomyelitis of the foot after puncture wounds revealed that: 1) osteomyelitis after puncture wounds is a infrequent but potentially serious complication, with significant morbidity; 2) osteomyelitis is frequently preceded by inadequate primary care for simple puncture wounds, and when treatment is appropriate, osteomyelitis usually can be avoided; 3) P. aeruginosa is the most commonly recovered organism; 4) the clinical presentation is characterized by a lack of systemic toxicity, paucity of laboratory abnormalities, and evidence of a localized infection process and the patient may be asymptomatic for a few days to several months after the injury before presentation of the osteomyelitis; and 5) once the infection has become established, treatment must be aggressive, including surgical debridement.

Adolescent

Human muscle fiber fine structure: morphometric data on controls.

Muscle fiber fine structure was quantitatively analyzed in 70 longitudinally and 65 transversely sectioned fibers from 10 control subjects without weakness. The average mitochondrial fraction of the fiber volume is close to 4 percent and the mean size of a mitochondrion is about 0.1 mum2. The sarcotubular surface area per unit fiber volume is close to 1.5 mum2/mum3 in transverse sections and 0.65 times this value in longitudinal sections. Only one-third of all fibers contain lipid droplets in the sectioned plane, and for all fibers the droplets account for approximately 0.12 percent of the fiber volume. Variations with the age and sex of the subjects and with different muscles were analyzed and the feasibility of typing human muscle fibers at the ultrastructural level was evaluated.

Adult

The association of scoliosis and congenital heart defects.

The effects of cardiac surgery on patients with congenital heart defects and the subsequent development of scoliosis were studied. A group of 998 patients with congenital heart defects who were less than sixteen years old were operated on at the Mayo Clinic during the ten-year period 1950 through 1959. Standing roentgenograms of the spine were made of 377 of the patients ten years or more after surgery. The ages of the patients at follow-up ranged from ten years and seven months to thirty-five years and three months, with a mean age of twenty-one years and four months. The average length of follow-up was fourteen years and eleven months. Of the 377 patients, thirty-two (8.5 per cent) had curves greater than 20 degrees. The female:male ratio of patients with congenital heart defects was 1:1, whereas of those who developed scoliosis it was 5:3. There was no correlation between scoliosis and the following: patient's sex, cardiac abnormality, size or side of the heart, side of the aortic arch, presence of cyanosis, age at surgery, number and type of surgical incisions, number and side of ribs removed, or number and type of surgical procedures.

Adolescent

Hematogenous pyogenic osteomyelitis in children.

Early diagnosis of acute hematogenous osteomyelitis is difficult. The diagnosis can be positively established only by isolation of the organism from bone or by histologic confirmation. The diagnosis should always be suspected when clinical signs are suggestive. In these cases aspirated material should be obtained for culture and the patient should be treated with antibiotics and observed closely. If the clinical response is good and no bone destruction occurs, surgical intervention may not be necessary. If the clinical response is not satisfactory or if bone destruction occurs, surgical treatment should be carried out to drain the area and to identify the etiologic organism. When osteomyelitis is associated with joint involvement, the prognosis is poor, and our data show no obvious improvement even with long-term antibiotic therapy. The key is prevention by early recognition and treatment. If culture fails to isolate a pathogenic organism, the prognosis appears to be good. Overall, in recent years the prognosis of hematogenous osteomyelitis has continued to improve, probably as a result of early detection and better antibiotic therapy.

Adolescent

Meniscal cyst and magnetic resonance imaging in childhood and adolescence.

We retrospectively reviewed 11 cases of meniscal cyst diagnosed at the Mayo Clinic from 1976 through 1990. Patient age ranged from 4 to 18 years (average 13 years). Two cases were diagnosed on clinical findings alone. Arthrograms were available in five cases. Magnetic resonance imaging (MRI) was used in four cases. These cases illustrate the difficulty in making the diagnosis of meniscal cyst. MRI is a useful tool for diagnosing meniscal cyst and aids in surgical planning. Because of the extensive differential diagnosis of the meniscal cyst, we recommend MRI in preoperative evaluation of soft tissue masses about the knee.

Adolescent

Brachymetatarsia of the first metatarsal treated by surgical lengthening.

The first metatarsal of six feet in four patients was surgically lengthened. Brachymetatarsia was caused by a congenital defect in two patients, nonunion after metatarsal osteotomy in one patient, and premature physeal closure associated with pin placement across the physis in one patient. In each patient, middiaphyseal osteotomy was performed, pins were placed into the proximal and distal metatarsal fragments, and an external distracting device was attached. After distraction, a fibular graft was inserted and the device was removed. The percentage of metatarsal length gained from the lengthening averaged 36% (range 12-68%). The fibular graft healed in the lengthened position in all patients.

Adolescent