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Biomedical subjects

H A Stickl

Publications and source records attributed to H A Stickl.

8 recordsLinked to original sources

[Traveling with children--what should be considered?].

A holiday shared by parents and children can be a delightful experience, provided the parents give due attention to the needs of their children dictated by age, mind, psychology and physique. If this is done, the children are more likely to look back on the holiday with pleasure rather than finding it a harrowing experience best forgotten. In particular in the case of very young and pre-school children, long journeys with young children are not a good idea, and may be associated with numerous disadvantages and health risks. The psychological and physical situation in to tropical and subtropical regions are discussed with respect to the planning of a suitable holiday.

Adaptation, Physiological↗

[Injury to the immune system by food contaminated by environmental toxins].

Immunity may be used as bioindicator for environmental toxic substances: Low level concentration of Pb, Cd, nitrosamines, Benzopyrene, nicotine and saturated fatty acids in food lead after application over months to a reduction of cellular and humoral immune response. After challenge by different infectious agents mortality was higher in the experimental group of mice. Up to date, investigations with low level doses of toxic agents in food running over a longer time had not been performed.

Animals↗

[The effect of Echinacea purpurea Moench on phagocytosis in granulocytes measured by chemiluminescence].

Chemiluminescence was used as an indicator for phagocytic activity of granulocytes induced by zymosan in whole blood. Luminol was used to amplify the luminescence measured. Methods and conditions of the trial were varied and the dependence on the methods applied became evident. The effects of echinacea-extract (Echinacin) and phorbolester (PMA) in various concentrations on phagocytic activity of whole blood heparinized with 10 I.E./ml heparin as well as on phagocytic activity of erytrocytolized blood were investigated. The reaction of the granulocytes--phagocytis and therefore chemilumenescence--under the influence of echinacea extract depends on the doses and methods applied. Therefore standardized methods and investigations of various immunoparameters as well as clinical investigations are necessary to prove the immunostimulative effect of socalled immunotherapeutics. This has not been undertaken up to now. Dose and method dependent single results cannot be a convincing justification for specific therapeutic medication.

Granulocytes↗

[The third generation vaccines].

The introduction of a new Hepatitis B-vaccine as the first licensed vaccine which is manufactored by gentechnological methods has encouraged generally to discuss advantages and problems of vaccines of the "Third Generation".

Child↗