Biomedical subjects
H A Waldron
Publications and source records attributed to H A Waldron.
Glutaraldehyde allergy in hospital workers.
Explore the source record for details and available documents.
Occupational health in the new NHS.
Explore the source record for details and available documents.
Prevalence and distribution of osteoarthritis in a population from Georgian and early Victorian London.
The prevalence of osteoarthritis was calculated in adult skeletons excavated from the crypt of Christ Church, Spitalfields in east London, which was used for burial between 1729 and 1869. Age and sex specific prevalences were also calculated for a subsample of the group for whom age and sex were accurately known from surviving coffin plates. Prevalences were slightly higher in men than in women, except for generalised osteoarthritis. The principal sites affected were the acromioclavicular joints, the facet joints of the spine, and the hands. Osteoarthritis of the large joints was relatively uncommon; osteoarthritis of the hip occurred in 4/360 (1.1%) of men and 10/346 (2.9%) of women and of the knee in 3/360 (0.8%) of men and 18/346 (5.2%) of women. This last difference was statistically significant. A comparison with modern data suggests that the prevalence of osteoarthritis at Spitalfields was lower than in the contemporary population, and some explanations for this apparent difference are considered.
Variations in the prevalence of spondylolysis in early British populations.
Crude prevalence rates of spondylolysis were estimated in skeletal populations from various periods. There was a steady increase in prevalence from 3.74% in Romano-British to 5.08% in medieval populations, but the rate fell considerably to 1.42% in a population from an 18th/19th century context. This trend was not statistically significant, however. The male/female ratio was approximately unity until the 18th/19th century when the expected male excess appeared. The lesions predominantly affected L5 and all were isthmic in type. Of the total of 52 cases, only four were unilateral. One occurred in the fourth cervical vertebra. There were few complications; spondylolisthesis was noted in four cases and in three there were osteoarthritic changes on the superior margin of the displaced lamina.
Delpech and the origins of occupational psychiatry.
Auguste-Louis Delpech (1818-80) has been remembered principally as the author of the first detailed description of the serious consequences of exposure to carbon disulphide. A close reading of his work suggests that his reputation has been seriously undervalued. The subsequent development of occupational psychiatry, with its emphasis on the distinction between the organic and the functional, may be traced through publications on carbon disulphide. It is argued that a contemporary approach to occupational psychiatry is long overdue.
Antibody response to hepatitis B vaccination.
Explore the source record for details and available documents.
Academic occupational health under threat.
Explore the source record for details and available documents.
COSHH and the NHS.
Explore the source record for details and available documents.
Occupational arthropathy: evidence from the past.
The relation between osteoarthritis and occupation was examined in a group of skeletons from the crypt of Christ Church, Spitalfields, in east London used for burial between 1729 and 1869. Of the total of 968 discrete skeletons excavated, 367 had legible coffin plates giving details of name, age, sex, and date of death. Various sources were used to find the occupations of the group for which these details were known. As many of those buried in the crypt were Huguenots interest centred on the relation between weaving and osteoarthritis of the hands but none was found using a case-control study. Further analyses failed to show a relation between occupation and osteoarthritis of the shoulder or osteoarthritis at any site. There was a statistically significant association between non-manual occupations and osteoarthritis of the spine, the reasons for which are not yet clear.
Organic solvents and presenile dementia: a case referent study using death certificates.
Occupational exposure to organic solvents has been implicated in the development of "presenile dementia" in several studies. The death certificates of all men aged under 65 dying in England and Wales bearing presenile dementia as cause of death were collected for the years 1970-9 (n = 557): control death certificates were obtained, matched for age and sex. No significant differences were found between the groups as regards estimated occupational exposure to either organic solvents or lead.
Employees with epilepsy in the National Health Service.
Explore the source record for details and available documents.
Effect of immersion on urinary lead excretion.
Explore the source record for details and available documents.
Solvents and the brain.
Explore the source record for details and available documents.