Chédiak-Higashi syndrome in a "Black' child.
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Black or African American↗
Biomedical subjects
H A de Beer
Publications and source records attributed to H A de Beer.
Non-diabetic necrobiosis lipoidica. Hitherto unrecognized papulonecrotic, nodulo-ulcerative and familial forms of the disease.
Necrobiosis lipoidica of the legs, in which deep ulcers resembling erythema induratum, gummas or a variety of other chronic progressive ulcerating skin diseases occur, is described. In 2 cases the lesions were precipitated by a crush injury elsewhere in the same leg, but not at the site of the ultimate lesions. In 2 further pairs of siblings the same problem arose as a familial complaint without trauma. These cases were distinguished by severe necrosis in the absence of diabetes.
Adult↗
Subcutaneous phycomycosis caused by Basidiobolus haptaosporus (Drechsler, 1947).
Subcutaneous phycomycosis in a Black child is reported, together with clinical, histological and mycological studies. This is the first case, to our knowledge, to be identified mycologically in South Africa. Oral potassium iodide gave an excellent therapeutic result.
Child, Preschool↗
[Contact dermatitis in industry].
The type of skin reactions which occur in commerce and industry and the causal agents are summarized.
Chromates↗
Chronic hydroquinone poisoning of the skin from skin-lightening cosmetics. A South African epidemic of ochronosis of the face in dark-skinned individuals.
Attention is drawn to the widespread use of bleaching preparations by Black women. These products often contain hydroquinone. They act efficiently as bleaching agents, but chronic oversaturation of the skin with hydroquinone eventually produces ochronosis. This complication has reached epidemic proportions in the Transvaal. Although the assay of hydroquinone in cosmetic products has not yet been standardized, we present some provisional results. The clinical, social and industrial aspects are also significant.
Black or African American↗
Topical nitrofurazone, a potent sensitizer of the skin and mucosae.
Although freely available, topical nitrofurazone (Furacin) frequently causes severe contact dermatitis, necessitating hospitalization. Six patients with sensitivity reactions to topical nitrofurazone are described. Our experience suggests that the free availability of this drug may increase the incidence of reactions due to its use, and should be condemned.
Adult↗