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Biomedical subjects

H Akbari

Publications and source records attributed to H Akbari.

16 recordsLinked to original sources

Shade trees reduce building energy use and CO2 emissions from power plants.

Urban shade trees offer significant benefits in reducing building air-conditioning demand and improving urban air quality by reducing smog. The savings associated with these benefits vary by climate region and can be up to $200 per tree. The cost of planting trees and maintaining them can vary from $10 to $500 per tree. Tree-planting programs can be designed to have lower costs so that they offer potential savings to communities that plant trees. Our calculations suggest that urban trees play a major role in sequestering CO2 and thereby delay global warming. We estimate that a tree planted in Los Angeles avoids the combustion of 18 kg of carbon annually, even though it sequesters only 4.5-11 kg (as it would if growing in a forest). In this sense, one shade tree in Los Angeles is equivalent to three to five forest trees. In a recent analysis for Baton Rouge, Sacramento, and Salt Lake City, we estimated that planting an average of four shade trees per house (each with a top view cross section of 50 m2) would lead to an annual reduction in carbon emissions from power plants of 16,000, 41,000, and 9000 t, respectively (the per-tree reduction in carbon emissions is about 10-11 kg per year). These reductions only account for the direct reduction in the net cooling- and heating-energy use of buildings. Once the impact of the community cooling is included, these savings are increased by at least 25%.

Air Conditioning↗

Sequential magnetic resonance monitoring of pulmonary flow with endovascular stents placed across the pulmonary valve in growing Swine.

BACKGROUND: Patients with endovascular stent implantation for the treatment of right ventricular outflow tract obstruction are often left with incomplete relief of the obstruction and significant pulmonary regurgitation. A noninvasive and reproducible method for monitoring such patients is desirable. MRI in the presence of a stent, however, has to overcome the problem of potential metallic artifacts. METHODS AND RESULTS: Under x-ray fluoroscopic guidance, endovascular nitinol stents were placed across the pulmonary valve in 6 young pigs to induce pulmonary regurgitation. Five additional pigs served as controls. Initial MRI was performed after 2 days (13.5+/-1.8 kg) and follow-up after 3 months (32+/-2.9 kg). Pulmonary flow volumes and regurgitant fraction were quantified by velocity-encoded cine (VEC) MRI through (VEC-TS) and distal to (VEC-DS) the stent. VEC-TS was compared with VEC-DS and volumetric measurements of left and right ventricular stroke volumes provided by cine MRI ("gold standard"). Antegrade and retrograde pulmonary flow volumes by VEC-TS were slightly but significantly less than those with VEC-DS and cine MRI. Excellent correlations (r>0.97) for phasic pulmonary flow volumes as measured by VEC-TS and VEC-DS were shown. Pulmonary regurgitant fraction increased from 32.8+/-15% to 49.6+/-17% (P<0.05) over the course of 3 months with VEC-TS. CONCLUSIONS: MRI demonstrates the progression of pulmonary regurgitation in growing swine. VEC MRI has the ability to quantify pulmonary blood flow inside the lumen of nitinol stents. MRI appears to be ideally suited for monitoring patients with endovascular nitinol stents in the pulmonary artery or pulmonary valve position.

Alloys↗

Leukocyte adhesion deficiency.

Leukocyte adhesion deficiency is a rare syndrome with autosomal recessive pattern of inheritance. An eleven-month-old boy, whose parents were first degree relatives, was referred to clinic with recurrent episodes of pneumonia, otitis and extensive necrotic wounds of perianal area since neonatal period. His umbilical cord had separated 30 days after birth. Laboratory findings included marked leukocytosis, chemotaxis abnormality, and very low levels of CD 11 (0.5%) and CD 18 (2%). Leukocyte Adhesion Defect (LAD) is rare genetic defect of a group of leukocyte membrane glycoproteins. LAD affects nearly one out of every million individuals and is characterized by recurrent bacterial and fungal infections of skin and mucous membranes, diminished pus formation, delayed umbilical cord separation, granulocytosis, poor wound healing and progressive periodontitis. This is the first report of a case of LAD in Isfahan of Iran.

Anus Diseases↗

Myocardial viability: magnetic resonance assessment of functional reserve and tissue characterization.

The determination of myocardial viability is crucial in patients with left ventricular dysfunction resulting from acute myocardial ischemia or chronic coronary artery disease. Viable myocardium will most likely benefit from revascularization procedures. However, the revascularization of scar tissue will not lead to improvement of ventricularfunction andfurthermore bears unnecessary riskfor the patient. Currently, echocardiographic and radionuclide techniques are the most established methods for the assessment of presence and extent of viable myocardium. Magnetic resonance imaging (MRI) also provides multiple approaches for determining viability of acute ischemically injured and hibernating myocardium. MRI can assess contractile reserve in a manner similar to echocardiography. Additionally, contrast-enhanced MRI can characterize myocardial ischemic injury, including the ability to discriminate viable from nonviable zones. Several new contrast media have been introduced for this purpose. This review addresses the progress toward the goal of defining myocardial viability based on MR techniques and focuses on the current and future role of MR in the assessment of viable myocardium.

Cell Membrane↗

MR contrast media for myocardial viability, microvascular integrity and perfusion.

Cardiovascular imaging requires an appreciation of rapidly evolving MR imaging sequences as well as careful utilization of intravascular, extracellular and intracellular MR contrast media. At the present time, clinical studies are restricted to the use of extracellular MR contrast media. MR imaging has the potential to noninvasively measure multiple parameters of the cardiovascular system in a single imaging session. Recent advances in fast and ultrafast MR imaging have considerably enhanced the capability of this technique, beyond the assessment of left ventricular wall motion and morphology into visualization of the coronary arteries and measurement of blood flow. During the course of the last several years, multiple strategies for imaging viable myocardium have been developed and validated using MR contrast media. Contrast enhanced dynamic MR imaging provides information regarding microvascular integrity and perfusion. Because these information can be provided noninvasively by MR imaging, repeated measurements can be performed in longitudinal studies to monitor the progression or regression of myocardial injury. Similar studies are needed to examine the effects of newly developed cardioprotective therapeutics. Development of suitable intravascular MR contrast medium may be essential for visualization of the coronary arteries and interventional therapies. MR imaging may emerge as one-stop-shop for evaluating the heart and coronary system. This capability will make MR imaging cost-effective in the first decade of this millennium.

Contrast Media↗

Single-shot echo-planar imaging of multiple sclerosis: effects of varying echo time.

Our aim was to determine the relative merits of short and long echo times (TE) with single-shot echo-planar imaging for imaging cerebral lesions such as multiple sclerosis. We examined seven patients with clinically definite multiple sclerosis were imaged at 1.5 T. Patients were scanned with spinecho, single-shot echo-planar imaging, using TEs of 45, 75, 105, and 135 ms. Region of interest (ROI) measurements were performed on 36 lesions at or above the level of the corona radiata. The mean image contrast (IC) was highest (231.1) for a TE of 45 ms, followed by 75 ms (218.9), 105 ms (217.9), and 135 ms (191.6). When mean contrast-to-noise ratios (C/N) were compared, the value was again highest (29.7) for TE 45 ms, followed by 75 ms (28.9), 105 ms (28.5), and 135 ms (26.3). In a lesion-by-lesion comparison, TE 45 ms had the highest IC and C/N in the largest number of cases (50 % and 47.2 %, respectively). IC and C/N for TE 45 ms were superior to those of 75 ms in 64% and 58%, respectively. These results support the use of relatively short TEs for single-shot echo-planar imaging in the setting of cerebral lesions such as multiple sclerosis.

Cerebral Cortex↗

Effect of fabrication technique on the erosion characteristics of polyanhydride matrices.

The aim of this study was to investigate the effect of device fabrication technique on the erosion characteristics of poly[1,3-bis(p-carboxyphenoxy) propane:sebacic acid] [p(CPP:SA)] 20:80 copolymer. Devices were prepared using melt-molding, solvent-casting, and compression-molding techniques and their erosion was followed by determining changes in device morphology, molecular weight, water uptake, mass loss, and release of monomers, with time of immersion in phosphate buffer pH 7.4 at 37 degrees C. Melt-molded devices had a very dense and uniform structure and displayed characteristics typical of surface eroding systems. Devices produced using a solvent-casting technique had a very porous structure with no detectable erosion zone and the erosion profiles were indicative of bulk rather than pure surface erosion. Compression-molded devices had a dense structure and revealed a faster rate of erosion than melt-molded devices. A comparison of the extent of changes of polymer molecular weight, water uptake, mass loss, and monomer release showed a marked dependence on the method of fabrication.

Chemical Phenomena↗

Superior mesenteric artery aneurysm in Behçet's disease.

Behçet's disease is a multisystem disorder characterized by recurrent orogenital ulcerations and uveitis. Vascular involvement can include both arteries and veins, with a preponderance of venous lesions. Aneurysms of splanchnic arteries due to Behçet's disease have been rarely reported. We present an unusual case of superior mesenteric artery aneurysm due to Behçet's disease diagnosed by ultrasonography and angiography.

Adult↗

Identification of pulmonary vein stenosis after radiofrequency ablation for atrial fibrillation using MRI.

Pulmonary vein stenosis is one of the frequent complications after radiofrequency ablation for atrial fibrillation. MRI plays an important role in depicting the pathoanatomic structure of the pulmonary veins, and measuring the blood flow velocity in the pulmonary veins before and after therapy, and is superior to transesophageal echocardiography for this purpose.

Aged↗