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Biomedical subjects

H Althoff

Publications and source records attributed to H Althoff.

At least 55 records · Page 3Linked to original sources
PubMed1980

[Morphological diagnosis: myocarditis (author's transl)].

On the basis of numerous post mortem examinations, polyetiology and diverse morphological variants of myocarditis are presented. With focal myocarditis the postmortal diagnosis may be left to chance. Histological routine examinations should encompass not only several parts of the left and right heart, but also the anterior septum. The Ladewig staining method has proven to be a suitable method for recognizing early changes of the myocard.

Autopsy↗
PubMed1978

[Cardiovascular tissue response to intracardiac pacemaking (author's transl)].

With transvenous intracardiac implantation of pacemakers after a few days already a fibrotic wall has developed around the impulse generator by a chronical proliferous process. Where the electrode has been advanced through the vein-wall and in the following veins the cable is wrapped cuff-like by increased collagenous fibres. Frequently these formed an adhesion with the inner vein-wall for quite some distance. Inside the heart, adhesion to the tricuspid valve may lead to insufficiency of this. The incorporation in the myocardium occurs as embedding in connective tissue. Here also chronical proliferous processes occur obviously. The electric conductiveness in the primary thrombo-cellular state after implantation is reduced rather than in late phase of hyaline building. In 12 instances of autopsy, 4 persons died a non-natural death (suicide). In one case, technical failure caused death, and once pulmonary embolism. In the other cases, the basic ailment seems to have been fatal. In four of these 6 instances, the scale of myocardial and endocardial tissue response to the pacemaker have aggravated certainly the prior process of disease. In conclusion, discerning opinions on fitness and safety in traffic and on the limitations of these therapeutical measures are ventilated.

Coronary Vessels↗
PubMed1977

[Sudden death from coronary disease in younger women (author's transl)].

Eleven sudden deaths from coronary disease were studied in women aged 29--44 years. These cases occured between 1971 and 1976 in the Institute for Forensic Medicine, University of Cologne, BRD. Postmortal morphological examinations resulted excessive stenosed coronary arteries caused by arteriosclerosis in all cases, in eight combined with acute obstructing thrombus. Our study group is not representative of the incidence of fatal coronary disease in the community. The prevailing conclusions about influence of sex hormones from oral contraceptives upon the development of arteriosclerosis, hypercoagulability and thrombosis demonstrate contrary evaluation. Our reflections about aetiology and pathogenesis from the pathomorphological findings don't substantiate a proof correlation between coronary disease or coronary thrombosis and oral contraceptions. Many other factors are equal important. The opinion of increased incidence and risk for death from coronary disease in users of oral hormonal contraceptions is not evident for us.

Adult↗
PubMed1977

[Additional post-mortem examination techniques to detect patho-morphological findings of nose and throat in cases of sudden infant death syndrome (SIDS) (author's transl)].

To detect histopathological findings in nose and throat. These methods are especially advisable in cases of sudden infant death syndrome, as it could be proved, that in 25 of 30 in this manner examined cases there were inflammatory processes of different extent up to necrotic rhinitis. The morphological findings as well as the accompanying information of anamnesis and the bacteriological findings are discussed. We consider, it advisable, to make use of the described additional investigational methods.

Autopsy↗
PubMed1976

[The problems of deaths by bolus aspiration ("cafe-coronary") (author's transl)].

Twentyseven fatal cases of suffocation by swallowing a bolus were analysed under different aspects. An attempt is made to interpret the functional disturbances which precede death, the causes for disturbance of swallowing and subsequent fatal reflex effects. The problems of judging the situation by the medical expert is discussed. Finally recommended therapeutic measures are critically evaluated to answer the question whether timely and adequate remedies truly exist.

Acute Disease↗
PubMed1976

[Critical examination of postmortem IgA-, IgG- and IgM serum levels in sudden unexpected deaths during infancy (author's transl)].

UNLABELLED: Postmortem concentration of the three immunoglobulins IgA, IgG and IgM has been studied by single radial immunodiffusion in 81 cases of sudden unexpected death in infancy and in 6 deaths between 2 and 11 years of age. The examinations of serum were repeated after several days after the sera had been kept at different temperatures. For comparison the serum immunoglobulin levels of IgA, IgG and IgM were determined in 11 corpses of adults directly after death and again 1 or 2 days later. RESULTS: With the radial immunodiffusion method postmortem serum immunglobulins are determinable. A critical estimation of postmortem IgA-, IgG- and IgM serum levels has to consider postmortem protein modifications and keeping sera at higher temperatures (+44 degrees C., + 20 degrees C.) For determinations at a later date sera must be kept at -35 degrees C. The measured postmortem serum levels of IgA and IgG in cases of sudden unexpected death in infancy correspond with the normal variation of value in healthy children of the same age. The lowest concentrations of IgG were found about the 5th. month in infancy. Many of the IgM levels were higher than the normal mean value in healthy children of the same age. This is not caused by postmortem influences. The higher IgM concentration in sera suggest an active immunological reaction before death.

Child↗