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Biomedical subjects

H Anttonen

Publications and source records attributed to H Anttonen.

10 recordsLinked to original sources

Detection of airborne reindeer epithelial antigen by enzyme-linked immunosorbent assay inhibition.

Hypersensitivity reactions to reindeer epithelial (RE) allergens have been recently demonstrated among reindeer herders. To determine the concentration of airborne RE antigens a method based on inhibition of the enzyme-linked immunosorbent assay (ELISA) was developed. Dust samples were collected in workshops where reindeer leather was processed and the workers had inhaled dry epithelial dust during their working shifts. Specific IgE to RE allergen could be detected in one of 5 workers. RE antigen concentrations varied from 0.01 microgram to 3.9 micrograms/m3 in the air of the workshop. All workers except one claimed work-associated respiratory symptoms.

Adult

Prevention of accidents in reindeer herding work.

In the northern part of Finland we have about 450,000 reindeer and their raising gives work to about 3,500 reindeer herders. In this study data on the occupational accidents of herders were collected by two questionnaires with an interval of 2 years. Based on the surveys of accident risks in various work phases 34 preventive measures were developed and information about them was passed on to the herders between the questionnaires. Most of the accidents occurred in the late autumn during slaughtering, gathering for separation and during separation work. The main causes of accidents were the slaughtering knife (30%) and the reindeer itself (25%). The most serious accidents were caused by snowmobiles and other terrain vehicles. The recommended preventive measures mostly dealt with the environment of permanent working places, personal protection and working habits. The follow-up questionnaire showed that the herders had implemented on an average 5.8 preventive measures. The incidence rate of accidents also decreased during the 2 years from 21 to 12 accidents/1000 working days. In conclusion these results show that it is possible to develop measures preventing accidents and to improve the safety in reindeer herders' work.

Accidents, Occupational

Safety in the use of four-wheeled all-terrain vehicles in Finland.

The aim of this study was to ascertain the use of four-wheeled all-terrain vehicles in Finland and estimate the safety in driving a four-wheeler. According to the importers there are about 3,000 four-wheelers in use in Finland. A questionnaire was sent to the owners of four-wheelers (n = 185), in which questions were asked about their use, protection used when driving, accidents that had occurred and suggestions for developing four-wheelers. One hundred three answers (response rate 56%) were received. The respondents reported minor injuries (15%) and dangerous situations: the four-wheeler had fallen over (35%) and the driver had fallen off the four-wheeler (20%). The accidents and dangerous situations were concentrated to occupational users who drove a lot in poor terrain. Four-wheeler driving was estimated to be more dangerous than snowmobile driving. According to the answers the most efficient measures to improve safety would be the use of a safety helmet and high boots when driving as well as the enforcement of an age limit for the driver. The technical properties of the four-wheelers could also be developed e.g. the leg room, foot board and protective roll bar.

Accident Prevention

No effect of experimental noise exposure on human pregnancy.

The effect of experimental noise exposure (15 minutes of 90-dB white noise via headphones) was examined on systolic, diastolic, and mean arterial pressures; heart rate; and stress hormones (ACTH, cortisol, prolactin, epinephrine, and norepinephrine) in normotensive and hypertensive pregnant women. No significant effects induced by noise exposure could be registered in these variables. Fetal and uterine blood circulation was also examined with a duplex pulsed Doppler system. No changes were seen on the fetal side as measured from the descending aorta in blood flow velocity (cm/second) or pulsatility or resistance indexes in either normotensive or hypertensive pregnancy. The only change observed was an increase in fetal heart rate in normotensive pregnancy. However, this increase could not be confirmed by cardiotocographic registration and is not clinically important. Uterine blood circulation was recorded from the proximal uterine artery on the placental side, and no effect of exposure was seen on pulsatility or resistance indexes.

Adult

[Cold weather work].

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Body Temperature Regulation

Toxicity of richterite in hemolysis test and macrophage cultures.

Richterite is a fibrous mineral associated with apatite deposits in eastern Finland. Fibre size features suggest potential toxicity but no data is available of fibrogenic effects on human lungs. The toxicity of richterite in a hemolysis test and in lung macrophage cultures was studied. In the hemolysis test richterite-rich samples showed the same degree of hemolysis as titanium dioxide whereas anthophyllite, crocidolite, chrysotile, wollastonite and quartz samples had distinctly higher degree of hemolysis. In the macrophage toxicity assay the percentage of dead cells was counted, and LDH, ASAT and acid phosphatase were determined from the culture medium. In this assay richterite showed lower toxicity than anthophyllite, crocidolite, chrysotile or quartz but gave higher values than titanium dioxide. Wollastonite showed similar level of toxicity. Differences were statistically highly significant. The results suggest that richterite (with wollastonite) belongs to a group of fibrous minerals which have distinctly smaller biological effect than traditional asbestos minerals.

Animals